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Protein Overview: apc10

General Information:
Name(s) found: apc10 / SPBC1A4.01 [Sanger Pombe]
Description(s) found:
Found 22 descriptions.
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  • anaphase-promoting complex subunit Apc10 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 189 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    anaphase-promoting complex [TASLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: activation of mitotic anaphase-promoting complex activity [IMPLink to PubMed article]
    cyclin catabolic process [IMPLink to PubMed article]
    anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [ICLink to PubMed article]
    mitotic metaphase/anaphase transition [ICLink to PubMed article]
    protein ubiquitination [ICLink to PubMed article]
    Molecular Function: ubiquitin-protein ligase activity [ICLink to PubMed article]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQIRQEALK KQKSETQKST EGFVDIGNLA QWTCSSEKSG FPIRLVRDDN IDTYWQSDGS  60
   61 QPHTIHIKFV KRVSIKYVSM YLQYTLDESY TPSTLRISAG TGFQDLEIVT TVQVEEPTGW 120
  121 VHVPVGDFGR NGLLDVHLIQ IKILANHQSG KDSHVRLIKI YAPEIEQPAI AVDEIPYTSL 180
  181 QFISRNQLR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..189] PSI-BLAST 60.69897 APC10/DOC1 subunit of the anaphase-promoting complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  8.2536490347155 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  7.94028983948676 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  6.95223443027718 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  5.78575924847122 bayes_pls_golite062009
  • binding
    		•  2.31774167130542 bayes_pls_golite062009
  • ligase activity
    		•  2.23368019733876 bayes_pls_golite062009
  • protein binding
    		•  1.90867517664953 bayes_pls_golite062009
  • fucose binding
    		•  1.8351563370158 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.47724057301404 bayes_pls_golite062009
  • DNA binding
    		•  1.32877230618244 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.744762162604188 bayes_pls_golite062009
  • hydrolase activity
    		•  0.690426836233441 bayes_pls_golite062009
  • kinase activity
    		•  0.667346867884307 bayes_pls_golite062009
  • protein kinase activity
    		•  0.615340190084121 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.509533284310982 bayes_pls_golite062009
  • transferase activity
    		•  0.212597910365422 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle