YRC Public Data Repository - Protein Structure Prediction

Protein:	apc10
Organism:	Schizosaccharomyces pombe
Length:	189 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for apc10.

Description	E-value	Query Range	Subject Range
APC10_ARATH - Anaphase-promoting complex subunit 10 OS=Arabidopsis thaliana GN=APC10 PE=1 SV=2	248.0	[0..16]	[189..20]
gi\|197245971, gi... - gi\|34851573\|ref\|XP_341669.1\| PREDICTED: similar to Anaphase-promoting complex subunit 10 (APC10) (Cy... APC10_MOUSE - Anaphase-promoting complex subunit 10 OS=Mus musculus GN=Anapc10 PE=1 SV=1 tr\|G3H9G3\|G3H9G3... - Anaphase-promoting complex subunit 10 OS=Cricetulus griseus GN=H671_3g9712 PE=3 SV=1	246.0	[0..8]	[189..6]
gi\|68440237 - gi\|68440237\|ref\|XP_690846.1\| PREDICTED: similar to Anaphase promoting complex subunit 10 (APC10) (Cy...	246.0	[0..8]	[189..6]
gi\|149698187 - gi\|149698187\|ref\|XP_001502007.1\| PREDICTED: similar to anaphase promoting complex subunit 10 [Equus ... ANAPC10 - anaphase promoting complex subunit 10 gi\|57096819 - gi\|57096819\|ref\|XP_532678.1\| PREDICTED: similar to Anaphase promoting complex subunit 10 (APC10) (Cy... tr\|F2Z4G9\|F2Z4G9... - Isoform of Q2YDH1, Anaphase-promoting complex subunit 10 OS=Bos taurus GN=ANAPC10 PE=3 SV=1 gi\|109075785, gi... - gi\|109075787\|ref\|XP_001094665.1\| PREDICTED: anaphase promoting complex subunit 10 isoform 4 [Macaca ... ENSPTRT00000030634 - null ENSCJAT00000005096 - null	245.0	[0..8]	[189..6]
APC10_BOVIN - Anaphase-promoting complex subunit 10 OS=Bos taurus GN=ANAPC10 PE=2 SV=1	245.0	[0..8]	[189..6]
gi\|56605928, gi\|... - gi\|56605928\|ref\|NP_001008467.1\| anaphase promoting complex subunit 10 [Gallus gallus], gi\|53130520\|e...	243.0	[0..8]	[189..6]
gi\|4836700 - gi\|4836700\|gb\|AAD30527.1\| anaphase promoting complex subunit 10 [Homo sapiens]	243.0	[0..8]	[189..6]
gi\|47209318 - gi\|47209318\|emb\|CAF92702.1\| unnamed protein product [Tetraodon nigroviridis]	241.0	[0..8]	[189..6]

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Predicted Domain #1

Region A:
Residues: [1-189]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQIRQEALK KQKSETQKST EGFVDIGNLA QWTCSSEKSG FPIRLVRDDN IDTYWQSDGS  60
   61 QPHTIHIKFV KRVSIKYVSM YLQYTLDESY TPSTLRISAG TGFQDLEIVT TVQVEEPTGW 120
  121 VHVPVGDFGR NGLLDVHLIQ IKILANHQSG KDSHVRLIKI YAPEIEQPAI AVDEIPYTSL 180
  181 QFISRNQLR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.69897
Match:	1jhjA
Description:	APC10/DOC1 subunit of the anaphase-promoting complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ubiquitin-protein ligase activity	8.2536490347155	bayes_pls_golite062009
small conjugating protein ligase activity	7.94028983948676	bayes_pls_golite062009
acid-amino acid ligase activity	6.95223443027718	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	5.78575924847122	bayes_pls_golite062009
binding	2.31774167130542	bayes_pls_golite062009
ligase activity	2.23368019733876	bayes_pls_golite062009
protein binding	1.90867517664953	bayes_pls_golite062009
fucose binding	1.8351563370158	bayes_pls_golite062009
nucleic acid binding	1.47724057301404	bayes_pls_golite062009
DNA binding	1.32877230618244	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.744762162604188	bayes_pls_golite062009
hydrolase activity	0.690426836233441	bayes_pls_golite062009
kinase activity	0.667346867884307	bayes_pls_golite062009
protein kinase activity	0.615340190084121	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.509533284310982	bayes_pls_golite062009
transferase activity	0.212597910365422	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: