YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. A protein complex that includes a ubiquitin-protein ligase and other proteins that may confer substrate specificity on the complex. A ubiquitin ligase complex found in the nucleus.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: anaphase-promoting complex
Acc: GO:0005680
Aspect: Cellular Component
Desc: A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
Synonyms:
  • APC
  • anaphase promoting complex
  • cyclosome
Proteins in PDR annotated with:
   This term: 107 [Search]
   Term or descendants: 107 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005680 - anaphase-promoting complex (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle