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Protein Overview: Pros45-PA

General Information:
Name(s) found: Pros45-PA / FBpp0076890 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • The gene Pros45 is referred to in FlyBase by the symbol Dmel\Pros45 (CG1489, FBgn0020369). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:21187087..21188690. It has the cytological map location 19F4. There is experimental evidence that it has the molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus; proteolysis. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 405 amino acids

    Gene Ontology:
    Cellular Component: proteasome regulatory particle, base subcomplex [ISS][NAS]
    cytoplasm [IEA]
    proteasome regulatory particle [IDA][ISS][NAS]
    proteasome complex [NAS]
    Biological Process: proteolysis [IDA][ISS]
    response to DNA damage stimulus [IMP]
    ubiquitin-dependent protein catabolic process [NAS]
    Molecular Function: ATPase activity [ISS][NAS]
    ATP binding [IEA]
    endopeptidase activity [IDA][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVTNRMEIE SAYHKGEGFR SYYIQKIEEL QLVVAEKHQN LRRLQAQRNE LNAKVRMLRE  60
   61 ELQLLQEQGS YVGEVVKPMD KKKVLVKVHP EGKFVVDLDK NIDINDVTPN CRVALRNESY 120
  121 TLHKILPNKV DPLVSLMMVE KVPDSTYEMV GGLDKQIKEI KEVIELPVKH PELFDALGIA 180
  181 QPKGVLLYGP PGTGKTLLAR AVAHHTECTF IRVSGSELVQ KFIGEGSRMV RELFVMAREH 240
  241 APSIIFMDEI DSIGSSRIES GSGGDSEVQR TMLELLNQLD GFEATKNIKV IMATNRIDIL 300
  301 DPALLRPGRI DRKIEFPPPN EEARLDILKI HSRKMNLTRG INLRKIAELM PGASGAEVKG 360
  361 VCTEAGMYAL RERRVHVTQE DFEMAVAKVM QKDSEKNMSI KKLWK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..405] PSI-BLAST 84.221849 VCP/p97


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle