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Protein Overview: FBpp0309478, Ran...

General Information:
Name(s) found: FBpp0309478 [FlyBase]
Ranbp21-PA / FBpp0074528 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=X:complement(19541608..19545333); ID=FBpp0309478; name=Ranbp21-PB; parent=FBgn0031051,FBtr0340614; dbxref=FlyBase:FBpp0309478,FlyBase_Annotation_IDs:CG12234-PB; MD5=acb6e0ec2e645fa12965f84510253de1; length=1241; release=r5.56; species=Dmel; [FlyBase]
  • The gene Ranbp21 is referred to in FlyBase by the symbol Dmel\Ranbp21 (CG12234, FBgn0031051). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19540617..19545958. It has the cytological map location 18D12-18D13. It is reported to have molecular function</span>: Ran GTPase binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: intracellular protein transport. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1241 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: intracellular protein transport [IEA]
    Molecular Function: protein transporter activity [IEA]
    binding [IEA]
    Ran GTPase binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQHGGTEAL AAELASAIDL VMNPMTQQQA RLEAYMACER FKEESPMCAQ VGLFLASSPQ  60
   61 SNQQVRHFGL QLIEYTIKYR WNCITHEEKV YIKDNAIKML NVGVGPAEDR SLLPTKDALS 120
  121 RIIVEMIKRE WPQQWSDLLP ELSQACTKGE AQTELVLLVF LRLVEDVALL QTIESNQRRK 180
  181 DMYQALNNNM NDIFEFFLRL VEQHVTAFRE TTRLCNYTKA NAHSRVVEMV LLTLSGFVEW 240
  241 VSIQHIMSSN GKLMHFLCIL LNDKAFQCNA AECLAQITNR KGQTKERKPL LQLFNEEPLR 300
  301 YIYQASQIPA DTSSTLAVEQ HLNFLKKLLQ VLNGMAQQLV ALWGKDDATQ RPVHLEVLLE 360
  361 CLLLLVQHPS LGLSHGSALI WQLLLKHEPS SKDFAMVNYI PKLIHTIAPR IVKLPYPASA 420
  421 SSPASLSTEA YIRLEHDSEE EYALYFFRCR TDFLEIFRLA TLVQPLVTYG YCEQWLQQRL 480
  481 RNAQIEADAE VKSGNVSCSV LDPVYLEWDA LVSVLDGVLS RILLVAERPS VPAGLRLLEE 540
  541 CLKLETINPL TYSILLSCIS ALFVFLSMSA CQITATNCVA MSGVSLLPRV LDKIFRALVM 600
  601 KPPNELEKVQ AKSAKNLRRH AASLLVKLAH KYPLLLLPVF EQINGHVELL LKEPGKHQLC 660
  661 RLMRTTLQEA LILISNHFCD FERQTLFIEH IVQDKRTEWL AFGDALKSPL DFMSFVGLDK 720
  721 PPIFAVEGAV TLQNRSRLLD ALHVVLGVVK RCTWPDDPER AQRGGFVIGC TELGNPICRN 780
  781 PATKHIVPLL SHVLSLMRVL NELFAPEALQ ALSEGYRGIH GMMEHEKKLL MGICALPTDP 840
  841 LDTTIRSEPT AFEKMQTFMM MVTEGCYHLM GSAGPSLGRD LYQLMGLSDA IVTNVFSRMD 900
  901 LVPDYRLRPI IRVFFKPFVY SCPPSFYDSV LVPLFAHLAP LMCERLTRRW IYIASLYESG 960
  961 QLDGEVNDTQ EVLEDQLNRT LTREYLDVLK IALVGGQIGA DHVAAGANAN SNSVAMENEE1020
 1021 HSMDSAPQSR AIQSALLSDI ISDLGGKLLR NGLIGNYVLM TLLKAIAWND GMCSMKAVNI1080
 1081 AAPVMRFLAA EKLMDENKAV TAFTAVLQGM QVHGQHEANQ SGLVTLGVQF YELLRPQFPI1140
 1141 LSEVLQHIPS VNAADIQKFD EKIAVAPVKG NKVDRAKKDI FKKLTAQLVG RSVNQLFRHE1200
 1201 VQIANLPPMQ SHKAKGSMGT TADIMDSNQN ASLARLFGPE K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..811] PSI-BLAST 77.69897 Karyopherin beta2
    2 View Details [812..964] PSI-BLAST 30.39794 Proteolytic fragment of CRM1 spanning six C-terminal HEAT repeats
    3 View Details [965..1034] deduced N/A No confident structure predictions are available.
    4 View Details [1035..1241] MSA 1.046986 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  4.58709163830613 bayes_pls_golite062009
  • nuclear export signal receptor activity
    		•  3.48172991171337 bayes_pls_golite062009
  • binding
    		•  2.91891696274037 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  2.74547353635661 bayes_pls_golite062009
  • transporter activity
    		•  2.48700774379895 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.26725422172281 bayes_pls_golite062009
  • protein binding
    		•  1.94427330399472 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  1.91487015967262 bayes_pls_golite062009
  • RNA binding
    		•  1.90646441530563 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.28481004323799 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.09652988954158 bayes_pls_golite062009
  • signal sequence binding
    		•  0.57106697498903 bayes_pls_golite062009
  • importin-alpha export receptor activity
    		•  0.259676026705859 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252495966234234 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.248585912061178 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.226380819487924 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.217517113570989 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.178770060806735 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.175241020572885 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.174922130116569 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.169755106399802 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.100181463251306 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0635404099346928 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0548082069333885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.052195223119721 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0405268469927988 bayes_pls_golite062009
  • mRNA binding
    		•  0.0364755031177104 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle