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Protein Overview: FBpp0311889, CG3...

General Information:
Name(s) found: FBpp0311889 [FlyBase]
CG32533-PA / FBpp0074555 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=X:complement(19368215..19368798,19370143..19370375,19370444..19371372,19371441..19371638,19371701..19372071,19372126..19372656,19372717..19373290); ID=FBpp0311889; name=CG32533-PB; parent=FBgn0052533,FBtr0346016; dbxref=FlyBase:FBpp0311889,FlyBase_Annotation_IDs:CG32533-PB; MD5=937235c6aadd57459f04573c664537ef; length=1139; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG32533 (CG32533, FBgn0052533). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19368178..19373345. It has the cytological map location 18C7. Based on sequence similarity, it is predicted to have molecular function</span>: helicase activity; ATP-dependent RNA helicase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1139 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: nuclear mRNA splicing, via spliceosome [ISS]
    Molecular Function: nucleic acid binding [IEA]
    ATP binding [IEA]
    helicase activity [ISS]
    ATP-dependent RNA helicase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRIKKKADE HASSRRRTQI NLIEFSFLDH KAELVGLLQA KSRQVGRSLV ENEADFWKFV  60
   61 GKYEAMMRST GQPVLPPRLA EAELSSMQPY HRSKHLALRL DADELLQEAR DQMQSQFRHI 120
  121 LLVYLDFRQT EKFQRIRKLR QTQRNLPIAR FRKDLREALD TSRVVIVAGD TGCGKSTQVP 180
  181 QYLYDFGYRS IACTQPRRLA CVSLCKRVAH ELLDDYGSRV AFQIRFERSR TKLTNILFIT 240
  241 EGLLLRQLAV AANLDQYDAL ILDEIHERNL FGDFLLGVTK CLLRARPQLK LILMSATINV 300
  301 ELFHGYFGEE GARLVQVPGR LFPIKLRYLP PPALELKAGQ ATSKRSQRNR IDPAPFVQVL 360
  361 SLIDQQYPTS ERGDVLIFVS GVNEIESVVE AVHEYATEQT HWLVLPLHSG QAIADQSKVF 420
  421 DYAPEGMRKC IVSTNIAETS LTVDGVRFVV DSGKVKEMNF DATCKGQRLK EFWVSKSSAD 480
  481 QRKGRAGRTG PGVCFRLYTA EQYNAFEAYP TPEIYRVPLD TMLLQMVSMG LPDVRAFPFI 540
  541 EAPETERIEQ TILALKQHCA LSVEEKITPL GRSLANLPVE LSIGKMLLMG SVFPEVEQLL 600
  601 TLAAMLSVQN PLTNRAHTDQ RCVRERESLE SDHGDLFTLV RLYNVWVQLK MRRDGTRQWC 660
  661 RRLGIEEQRF YEVTKLRQQF QRILESCGMV VASDSDSQLT SAERATRHGE LRQLKAMKRR 720
  721 QRFEQPRQRK LLKQSAGRVA EDEEEQEEAQ GDDMRDVDFR LRFDPRQLAL LERSSRLDRH 780
  781 SVVVLLKLLL GSGFYPQLAI SDEFNYCKGG GQQFFHTRLK PFVLQHPNSQ FAKHFELLKL 840
  841 TESDLLPKPD FYTPKLPLSK RHQLLCYQSL LETAKPYLIN CIRLPAAQTL LLFSFAIDTN 900
  901 AGITQIACDG WLGLDLPMPG SGMELLRRAI ELRRRWSRLL YDKLDDLKSK QESPSHSSDD 960
  961 RSSALWQDLV DYMALDVAYA IRRLLPADIK RLYTHQAPSA RLAELKENPF AVDFPMTPNE1020
 1021 EKGGLNVSEH VVYSCLAEQQ WTTAMDATLR AEPWQCTRCD FELEEFDVLE QLVHRSKCKR1080
 1081 RKAQESRTAK TTSTESSTEV ASSSSSHSSG GYYCNSCKRE LRLTTIDILR HKKQCRNNK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] deduced N/A No confident structure predictions are available.
    2 View Details [80..528] PSI-BLAST 60.154902 No description for 2j0qA was found.
    3 View Details [529..631] deduced N/A No confident structure predictions are available.
    4 View Details [632..819] MSA 2.622994 View MSA. No confident structure predictions are available.
    5 View Details [820..970] deduced N/A No confident structure predictions are available.
    6 View Details [971..1139] FFAS03 4.9 No description for 2i13A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
    		• 4.704140727858 bayes_pls_golite062009
  • RNA binding
    		•  2.29590582680214 bayes_pls_golite062009
  • binding
    		•  2.05253348982328 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.57653963868443 bayes_pls_golite062009
  • RNA helicase activity
    		•  1.42791449104435 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.41477043612798 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  1.36724390116598 bayes_pls_golite062009
  • DNA binding
    		•  1.11699929651302 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.989226939888218 bayes_pls_golite062009
  • hydrolase activity
    		•  0.770112659770838 bayes_pls_golite062009
  • mRNA binding
    		•  0.76699944561918 bayes_pls_golite062009
  • helicase activity
    		•  0.6191010101321 bayes_pls_golite062009
  • structural molecule activity
    		•  0.596382945962261 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.461763181659193 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.458831409927227 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.455976987338331 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.422944846459286 bayes_pls_golite062009
  • snRNA binding
    		•  0.418985924846052 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • nucleotide binding
    		•  0.114848452385726 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.10713474095071 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0916519414118148 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0915913646217636 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0434163635422169 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle