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Protein Overview: CG8915-PA, FBpp0...

General Information:
Name(s) found: FBpp0308827 [FlyBase]
CG8915-PA / FBpp0074221 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=X:complement(17135851..17137895,17137957..17138164,17138267..17138944); ID=FBpp0308827; name=CG8915-PB; parent=FBgn0030833,FBtr0339780; dbxref=FlyBase:FBpp0308827,FlyBase_Annotation_IDs:CG8915-PB; MD5=292e1f17965a51e8a95ce0ba65dfa32b; length=976; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8915 (CG8915, FBgn0030833). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:17135295..17139028. It has the cytological map location 15F4. Based on sequence similarity, it is predicted to have molecular function</span>: helicase activity; ATP-dependent RNA helicase activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 976 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: nucleic acid binding [IEA]
    ATP binding [IEA]
    helicase activity [ISS]
    ATP-dependent RNA helicase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADSEEAVKR GRRQGRKKAQ PMPEQAVVLV VNGRVTGGPK GTGKQKTRPG KNAKADAGDK  60
   61 LKSEDEKMLR QLVDDFLQSC EPEKQLPGLT KAQRSHVHRL AQHRGLKTVS KGPEENRVLF 120
  121 ISRPQSDGQQ QYILCNTKLD ICPPLLDVLG QMAGNVERRL MNSVGDLKCN KQQYKDIRLP 180
  181 SNFGLVGQRL IPPPQSNRNR NIQHERRSLP IYKQRESILN VLQRDQVLII KGATGSGKST 240
  241 QLPQYILEWA AEHRAPVRIV VSQPRRIAAI SVSERISKER GEAPGTTVGY NIRMNRQCSS 300
  301 NTVLMLTTSG CLLRALAMDK KSFFKNTTHL IIDEAHERDL DTDFLLLATK LELQKNPHLR 360
  361 LVLMSATMDL EALSNYFGGG TVMDVEGRSF EVSIYHLEDI LSKTGYMHPR MEKFLGKPTG 420
  421 KETPSELLAA YYGGNTIVHP DIDNDLIVSL LELLLRQGDA GAVIVYLPGY SDMTSLLARL 480
  481 ESSLPREQIT IILLHSQVDN SEQRKVFRTY PGVRLKIILS TNIGQTSITI PDLLYVIDTG 540
  541 LAKMKTYDST IDASQLTLTW ISQADAKQRA GRAGRVCHGN CYRLYDNDRM ARMNLYTIPE 600
  601 IMRRTLDEIC LLTKLAAPDK KIENFLALAL DTPPKDAVMQ SCSRLKLLGV LDERDEVTPL 660
  661 GHIVAELPLG VQIGKCLVYS IYLRCLDSMI IIAAYHSVRD PFVLNIERGK KSGQQISRVL 720
  721 FAGDGMSDSL AVIKLYEEFT NLKRKDIGDF CERNFICRNA MEMFVSAAST LRDTVYRIFR 780
  781 FSEASARLAS SFNNDTNMIR LALTAGLYPK LAYMDRENKN QLVAEGDPLV QVSRSSCLRG 840
  841 KKKQKDLASE WILFVEKTRT ADQISSLEHT TLVSGLMVAL AGGKRFITEA HGSEMLLCLD 900
  901 SWIRLKCPAE FGLQLHKVRM LTDREFAKLV ATRKLSLMSD FIGPETVRRL LEADVPSTCL 960
  961 AEGKSLLDRD NCDNDF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] FFAS03 3.35 Solution structure of the R3H domain from human hypothetical protein BAA76846
    2 View Details [141..191] PSI-BLAST 60.69897 No description for 2db3A was found.
    3 View Details [192..655] PSI-BLAST 28.221849 Structure of the RecQ Catalytic Core
    4 View Details [656..741] deduced N/A No confident structure predictions are available.
    5 View Details [742..892] Pfam 21.721246 No description for PF07717.7 was found. No confident structure predictions are available.
    6 View Details [893..976] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.89418885407856 bayes_pls_golite062009
  • DNA binding
    		•  1.50596754488506 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.46911563206977 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.40070005217107 bayes_pls_golite062009
  • protein binding
    		•  0.641271951376049 bayes_pls_golite062009
  • catalytic activity
    		•  0.307971467423079 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.104498084588774 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
    		• 4.704140727858 bayes_pls_golite062009
  • binding
    		•  2.44689197844883 bayes_pls_golite062009
  • RNA binding
    		•  2.29590582680214 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.57653963868443 bayes_pls_golite062009
  • RNA helicase activity
    		•  1.42791449104435 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.41477043612798 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  1.36724390116598 bayes_pls_golite062009
  • DNA binding
    		•  1.11699929651302 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.989226939888218 bayes_pls_golite062009
  • mRNA binding
    		•  0.76699944561918 bayes_pls_golite062009
  • helicase activity
    		•  0.6191010101321 bayes_pls_golite062009
  • motor activity
    		•  0.61636596887462 bayes_pls_golite062009
  • structural molecule activity
    		•  0.596382945962261 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.461763181659193 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.458831409927227 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.455976987338331 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.422944846459286 bayes_pls_golite062009
  • snRNA binding
    		•  0.418985924846052 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.338958888186454 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • translation release factor activity
    		•  0.178286731022211 bayes_pls_golite062009
  • translation termination factor activity
    		•  0.151456842619444 bayes_pls_golite062009
  • nucleotide binding
    		•  0.114848452385726 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.10713474095071 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0916519414118148 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0915913646217636 bayes_pls_golite062009
  • protein binding
    		•  0.071010918255742 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0434163635422169 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.0272673919333979 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle