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View Structure Prediction Details

Protein: CG8915-PA, FBpp0...
Organism: Drosophila melanogaster
Length: 976 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG8915-PA, FBpp0....

Description E-value Query
Range		 Subject
Range
gi|114145427, gi... - gi|37654286|gb|AAQ96248.1| LRRGT00035 [Rattus norvegicus], gi|114145427|ref|NP_001041309.1| DEAH (As...
 633.0 [0..3] [919..328]

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Predicted Domain #1
Region A:
Residues: [1-140] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADSEEAVKR GRRQGRKKAQ PMPEQAVVLV VNGRVTGGPK GTGKQKTRPG KNAKADAGDK  60
   61 LKSEDEKMLR QLVDDFLQSC EPEKQLPGLT KAQRSHVHRL AQHRGLKTVS KGPEENRVLF 120
  121 ISRPQSDGQQ QYILCNTKLD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.35
Match: 1whrA
Description: Solution structure of the R3H domain from human hypothetical protein BAA76846
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.89418885407856 bayes_pls_golite062009
DNA binding 1.50596754488506 bayes_pls_golite062009
nucleic acid binding 1.46911563206977 bayes_pls_golite062009
transcription regulator activity 1.40070005217107 bayes_pls_golite062009
protein binding 0.641271951376049 bayes_pls_golite062009
catalytic activity 0.307971467423079 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.104498084588774 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [141-191] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ICPPLLDVLG QMAGNVERRL MNSVGDLKCN KQQYKDIRLP SNFGLVGQRL I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.69897
Match: 2db3A
Description: No description for 2db3A was found.

Predicted Domain #3
Region A:
Residues: [192-655] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPQSNRNRN IQHERRSLPI YKQRESILNV LQRDQVLIIK GATGSGKSTQ LPQYILEWAA  60
   61 EHRAPVRIVV SQPRRIAAIS VSERISKERG EAPGTTVGYN IRMNRQCSSN TVLMLTTSGC 120
  121 LLRALAMDKK SFFKNTTHLI IDEAHERDLD TDFLLLATKL ELQKNPHLRL VLMSATMDLE 180
  181 ALSNYFGGGT VMDVEGRSFE VSIYHLEDIL SKTGYMHPRM EKFLGKPTGK ETPSELLAAY 240
  241 YGGNTIVHPD IDNDLIVSLL ELLLRQGDAG AVIVYLPGYS DMTSLLARLE SSLPREQITI 300
  301 ILLHSQVDNS EQRKVFRTYP GVRLKIILST NIGQTSITIP DLLYVIDTGL AKMKTYDSTI 360
  361 DASQLTLTWI SQADAKQRAG RAGRVCHGNC YRLYDNDRMA RMNLYTIPEI MRRTLDEICL 420
  421 LTKLAAPDKK IENFLALALD TPPKDAVMQS CSRLKLLGVL DERD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.221849
Match: 1oywA
Description: Structure of the RecQ Catalytic Core
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
4.704140727858 bayes_pls_golite062009
binding 2.44689197844883 bayes_pls_golite062009
RNA binding 2.29590582680214 bayes_pls_golite062009
structural constituent of ribosome 1.57653963868443 bayes_pls_golite062009
RNA helicase activity 1.42791449104435 bayes_pls_golite062009
nucleic acid binding 1.41477043612798 bayes_pls_golite062009
RNA-dependent ATPase activity 1.39335733374328 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.36724390116598 bayes_pls_golite062009
DNA binding 1.11699929651302 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription regulator activity 0.989226939888218 bayes_pls_golite062009
mRNA binding 0.76699944561918 bayes_pls_golite062009
helicase activity 0.6191010101321 bayes_pls_golite062009
motor activity 0.61636596887462 bayes_pls_golite062009
structural molecule activity 0.596382945962261 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.461763181659193 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.458831409927227 bayes_pls_golite062009
pyrophosphatase activity 0.455976987338331 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.422944846459286 bayes_pls_golite062009
snRNA binding 0.418985924846052 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.338958888186454 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
ATP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
translation release factor activity 0.178286731022211 bayes_pls_golite062009
translation termination factor activity 0.151456842619444 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
protein binding 0.071010918255742 bayes_pls_golite062009
transcription factor activity 0.0434163635422169 bayes_pls_golite062009
cytoskeletal protein binding 0.0272673919333979 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [656-741] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVTPLGHIVA ELPLGVQIGK CLVYSIYLRC LDSMIIIAAY HSVRDPFVLN IERGKKSGQQ  60
   61 ISRVLFAGDG MSDSLAVIKL YEEFTN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [742-892] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKRKDIGDFC ERNFICRNAM EMFVSAASTL RDTVYRIFRF SEASARLASS FNNDTNMIRL  60
   61 ALTAGLYPKL AYMDRENKNQ LVAEGDPLVQ VSRSSCLRGK KKQKDLASEW ILFVEKTRTA 120
  121 DQISSLEHTT LVSGLMVALA GGKRFITEAH G

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 21.721246
Match: PF07717.7
Description: No description for PF07717.7 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [893-976] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEMLLCLDSW IRLKCPAEFG LQLHKVRMLT DREFAKLVAT RKLSLMSDFI GPETVRRLLE  60
   61 ADVPSTCLAE GKSLLDRDNC DNDF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle