Protein Overview: Gbeta13F-PB, Gbe...

General Information:
Name(s) found:	FBpp0303987 [FlyBase] Gbeta13F-PF / FBpp0089185 [FlyBase] Gbeta13F-PE / FBpp0089184 [FlyBase] Gbeta13F-PC / FBpp0089182 [FlyBase] Gbeta13F-PA / FBpp0073921 [FlyBase] Gbeta13F-PB / FBpp0073920 [FlyBase]
Description(s) found: Found 93 descriptions. SHOW ALL	type=protein; loc=X:15755807..15756829; ID=FBpp0303987; name=Gbeta13F-PG; parent=FBgn0001105,FBtr0331597; dbxref=REFSEQ:NP_996461,GB_protein:AAS65361,FlyBase:FBpp0303987,FlyBase_Annotation_IDs:CG10545-PG; MD5=fa40dba61b9c9701457fcc781f1988b2; length=340; release=r5.56; species=Dmel; [FlyBase] The gene G protein Ă?Ă?Â˛-subunit 13F is referred to in FlyBase by the symbol Dmel\GĂ?Ă?Â˛13F (CG10545, FBgn0001105). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15754159..15756919. It has the cytological map location 13F16. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. There is experimental evidence that it is involved in the biological process</span>: asymmetric neuroblast division; actin filament organization. 15 alleles are reported. The phenotype of these alleles is annotated with: embryonic neuroblast. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] The gene G protein Ă?Ă?Â˛-subunit 13F is referred to in FlyBase by the symbol Dmel\GĂ?Ă?Â˛13F (CG10545, FBgn0001105). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15754159..15756919. It has the cytological map location 13F16. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. There is experimental evidence that it is involved in the biological process</span>: asymmetric neuroblast division; actin filament organization. 15 alleles are reported. The phenotype of these alleles is annotated with: embryonic neuroblast. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] The gene G protein Ă?Ă?Â˛-subunit 13F is referred to in FlyBase by the symbol Dmel\GĂ?Ă?Â˛13F (CG10545, FBgn0001105). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15754159..15756919. It has the cytological map location 13F16. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. There is experimental evidence that it is involved in the biological process</span>: asymmetric neuroblast division; actin filament organization. 15 alleles are reported. The phenotype of these alleles is annotated with: embryonic neuroblast. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] The gene G protein Ă?Ă?Â˛-subunit 13F is referred to in FlyBase by the symbol Dmel\GĂ?Ă?Â˛13F (CG10545, FBgn0001105). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15754159..15756919. It has the cytological map location 13F16. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. There is experimental evidence that it is involved in the biological process</span>: asymmetric neuroblast division; actin filament organization. 15 alleles are reported. The phenotype of these alleles is annotated with: embryonic neuroblast. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] The gene G protein Ă?Ă?Â˛-subunit 13F is referred to in FlyBase by the symbol Dmel\GĂ?Ă?Â˛13F (CG10545, FBgn0001105). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15754159..15756919. It has the cytological map location 13F16. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. There is experimental evidence that it is involved in the biological process</span>: asymmetric neuroblast division; actin filament organization. 15 alleles are reported. The phenotype of these alleles is annotated with: embryonic neuroblast. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	340 amino acids
Gene Ontology:
Cellular Component:	heterotrimeric G-protein complex [ISS][NAS]
Biological Process:	G-protein coupled receptor protein signaling pathway [ISS][NAS] apical protein localization [TAS] actin filament organization [IMP] asymmetric neuroblast division [IMP]
Molecular Function:	GTPase activity [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNELDSLRQE AESLKNAIRD ARKAACDTSL LQAATSLEPI GRIQMRTRRT LRGHLAKIYA  60
   61 MHWGNDSRNL VSASQDGKLI VWDSHTTNKV HAIPLRSSWV MTCAYAPSGS YVACGGLDNM 120
  121 CSIYNLKTRE GNVRVSRELP GHGGYLSCCR FLDDNQIVTS SGDMSCGLWD IETGLQVTSF 180
  181 LGHTGDVMAL SLAPQCKTFV SGACDASAKL WDIREGVCKQ TFPGHESDIN AVTFFPNGQA 240
  241 FATGSDDATC RLFDIRADQE LAMYSHDNII CGITSVAFSK SGRLLLAGYD DFNCNVWDTM 300
  301 KAERSGILAG HDNRVSCLGV TENGMAVATG SWDSFLRVWN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

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Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
	6.67009948605948	bayes_pls_golite062009
structural molecule activity	5.05435272846365	bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific)	4.71992275913384	bayes_pls_golite062009
GTPase activity	4.02994814377904	bayes_pls_golite062009
actin binding	3.86142918698875	bayes_pls_golite062009
RNA binding	3.77273677738815	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.25521258308263	bayes_pls_golite062009
cytoskeletal protein binding	3.1056443224755	bayes_pls_golite062009
tubulin binding	2.76945430061825	bayes_pls_golite062009
microtubule binding	2.72684103222924	bayes_pls_golite062009
dynein binding	2.54821997913979	bayes_pls_golite062009
binding	2.42570478946173	bayes_pls_golite062009
transcription regulator activity	2.3610959773142	bayes_pls_golite062009
nucleic acid binding	2.30918780727915	bayes_pls_golite062009
transcription repressor activity	2.29049708962212	bayes_pls_golite062009
snoRNA binding	2.27164613239345	bayes_pls_golite062009
unfolded protein binding	2.07597866771866	bayes_pls_golite062009
dynactin binding	2.07556426531897	bayes_pls_golite062009
actin filament binding	2.0735069176589	bayes_pls_golite062009
histone methyltransferase activity	1.85632145559025	bayes_pls_golite062009
DNA binding	1.71685536470455	bayes_pls_golite062009
G-protein-coupled receptor binding	1.63631972867316	bayes_pls_golite062009
transcription corepressor activity	1.41752877005447	bayes_pls_golite062009
protein methyltransferase activity	1.35170368882651	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	1.22384651674093	bayes_pls_golite062009
protein binding	1.21879977456466	bayes_pls_golite062009
transporter activity	1.21549336905926	bayes_pls_golite062009
lysine N-methyltransferase activity	1.15313682561559	bayes_pls_golite062009
protein-lysine N-methyltransferase activity	1.15313682561559	bayes_pls_golite062009
histone-lysine N-methyltransferase activity	1.15313682561559	bayes_pls_golite062009
receptor activity	1.12819778129653	bayes_pls_golite062009
transcription factor activity	1.08768505897883	bayes_pls_golite062009
mRNA binding	1.05053985350578	bayes_pls_golite062009
microtubule plus-end binding	1.01166033978052	bayes_pls_golite062009
myosin binding	0.989691178611801	bayes_pls_golite062009
molecular transducer activity	0.974380908248463	bayes_pls_golite062009
signal transducer activity	0.974380908248463	bayes_pls_golite062009
protein transporter activity	0.964340340346761	bayes_pls_golite062009
angiotensin receptor binding	0.920323565472959	bayes_pls_golite062009
type 1 angiotensin receptor binding	0.920323565472959	bayes_pls_golite062009
substrate-specific transporter activity	0.734793983890004	bayes_pls_golite062009
histone binding	0.685319917508843	bayes_pls_golite062009
transcription factor binding	0.489473003915035	bayes_pls_golite062009
dynein intermediate chain binding	0.443846546939402	bayes_pls_golite062009
insulin receptor binding	0.43316396073854	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.426429095658617	bayes_pls_golite062009
kinase activity	0.387572734234845	bayes_pls_golite062009
receptor binding	0.316169754698691	bayes_pls_golite062009
transcription cofactor activity	0.30761651528651	bayes_pls_golite062009
myosin heavy chain kinase activity	0.231534552000461	bayes_pls_golite062009
protein kinase activity	0.229242350006544	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.226335610368636	bayes_pls_golite062009
enzyme regulator activity	0.161639372576406	bayes_pls_golite062009
myosin II binding	0.12060669039328	bayes_pls_golite062009
structural constituent of cytoskeleton	0.118975415284669	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.00585398682921312	bayes_pls_golite062009
N-methyltransferase activity	0.00335766408304172	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..340]	PSI-BLAST	86.39794	beta1-subunit of the signal-transducing G protein heterotrimer

Protein Overview: Gbeta13F-PB, Gbe...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: