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Protein Overview: antdh-PA

General Information:
Name(s) found: antdh-PA / FBpp0073324 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene antdh is referred to in FlyBase by the symbol Dmel\antdh (CG1386, FBgn0026268). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11062048..11063091. It has the cytological map location 10A10. Based on sequence similarity, it is predicted to have molecular function</span>: carbonyl reductase (NADPH) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 250 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: oxidation reduction [IEA]
    Molecular Function: carbonyl reductase (NADPH) activity [ISS]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERWQNRVAV VTGASSGIGS AIAKDLVLAG MTVVGLARRV DRVKELQREL PAEKRGKLFA  60
   61 LYCDVGNESS VNEAFDWIIQ KLGAIDVLVN NAGTLQPGYL VDMNPAVMQQ VLQTNIMGIV 120
  121 LCTQRAVRSM RERKFDGHVV LINSILGHKT MTATEGVAPD VNVYPPSKHA VTALAEGYRQ 180
  181 EFFGLGTRIK ITSVSPGVVD TEIVPDSIRE AIKDRMLHSE DIAQGVLYAI ATPPHVQVHE 240
  241 LIIKPLGETM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..250] PSI-BLAST 52.69897 Structure of human putative dehydrogenase MGC4172 in complex with NADP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  2.50453100919665 bayes_pls_golite062009
  • structural molecule activity
    		•  2.31813292180084 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  2.04225907952394 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  2.03461533859253 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  2.01043991420942 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • steroid dehydrogenase activity
    		•  1.75109362865449 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.55012034958204 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  1.23679054027553 bayes_pls_golite062009
  • alcohol binding
    		•  1.07158175924364 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  1.01627645289834 bayes_pls_golite062009
  • binding
    		•  0.982999356179965 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  0.867909552357575 bayes_pls_golite062009
  • retinal dehydrogenase activity
    		•  0.69372321031969 bayes_pls_golite062009
  • 3-oxoacyl-[acyl-carrier-protein] reductase activity
    		•  0.604742541607263 bayes_pls_golite062009
  • 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
    		•  0.583772223704381 bayes_pls_golite062009
  • DNA binding
    		•  0.525227236870065 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.459537641913493 bayes_pls_golite062009
  • retinol binding
    		•  0.343379136183648 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  0.311551606659739 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.258223964404048 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.177044638410302 bayes_pls_golite062009
  • coenzyme binding
    		•  0.0812901552017963 bayes_pls_golite062009
  • ethanol binding
    		•  0.0448614072391299 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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