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Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: carbonyl reductase (NADPH) activity
Acc: GO:0004090
Aspect: Molecular Function
Desc: Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
Synonyms:
  • NADPH-dependent carbonyl reductase activity
  • ALR3
  • NADPH2-dependent carbonyl reductase activity
  • carbonyl reductase activity
  • prostaglandin 9-ketoreductase activity
  • xenobiotic ketone reductase activity
  • nonspecific NADPH-dependent carbonyl reductase activity
  • secondary-alcohol:NADP+ oxidoreductase activity
  • aldehyde reductase I activity
  • aldehyde reductase 1
Proteins in PDR annotated with:
   This term: 16 [Search]
   Term or descendants: 16 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004090 - carbonyl reductase (NADPH) activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle