YRC Public Data Repository - Protein Structure Prediction

Protein:	antdh-PA
Organism:	Drosophila melanogaster
Length:	250 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for antdh-PA.

Description	E-value	Query Range	Subject Range
gi\|146296617, gi... - gi\|82501013\|ref\|ZP_00886394.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Caldicellulosiruptor sacc...	314.0	[0..1]	[250..1]
FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima GN=fabG PE=3 SV=1 FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / D...	313.0	[0..3]	[250..2]
gi\|18310052, gi\|... - gi\|18310052\|ref\|NP_561986.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens st...	309.0	[0..4]	[250..2]
gi\|115250215, gi... - gi\|126698778\|ref\|YP_001087675.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile 6... gi\|255306086 - gi\|255306086\|ref\|ZP_05350258.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile AT... gi\|255100197 - gi\|255100197\|ref\|ZP_05329174.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC...	307.0	[0..1]	[250..1]
gi\|255313843 - gi\|255313843\|ref\|ZP_05355426.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255516524 - gi\|255516524\|ref\|ZP_05384200.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255649624 - gi\|255649624\|ref\|ZP_05396526.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|254974717 - gi\|254974717\|ref\|ZP_05271189.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255092105 - gi\|255092105\|ref\|ZP_05321583.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile CI... gi\|90575404, gi\|... - gi\|90575404\|ref\|ZP_01231888.1\| hypothetical protein CdifQ_02001165 [Clostridium difficile QCD-32g58]...	306.0	[0..1]	[250..1]
gi\|168210762, gi... - gi\|170711222\|gb\|EDT23404.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens B st... gi\|110675446, gi... - gi\|110800799\|ref\|YP_695772.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens A... gi\|170660709, gi... - gi\|170660709\|gb\|EDT13392.1\| 3-oxoacyl- reductase [Clostridium perfringens E str. JGS1987], gi\|168207...	304.0	[0..4]	[250..2]
gi\|110803752, gi... - gi\|110803752\|ref\|YP_698460.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens S...	304.0	[0..4]	[250..2]
gi\|89098688, gi\|... - gi\|89098688\|ref\|ZP_01171570.1\| beta-ketoacyl-acyl carrier protein reductase [Bacillus sp. NRRL B-149...	303.0	[0..3]	[250..2]
gi\|20807919 - gi\|20807919\|ref\|NP_623090.1\| Dehydrogenase with different specificities (related to short-chain alco... gi\|20807919, gi\|... - gi\|20807919\|ref\|NP_623090.1\| dehydrogenase [Thermoanaerobacter tengcongensis MB4], gi\|20516487\|gb\|AA...	303.0	[0..5]	[250..4]
gi\|77636803, gi\|... - gi\|77687397\|ref\|ZP_00802638.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Alkaliphilus metalliredig...	301.0	[0..1]	[250..1]

Back

Predicted Domain #1

Region A:
Residues: [1-250]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERWQNRVAV VTGASSGIGS AIAKDLVLAG MTVVGLARRV DRVKELQREL PAEKRGKLFA  60
   61 LYCDVGNESS VNEAFDWIIQ KLGAIDVLVN NAGTLQPGYL VDMNPAVMQQ VLQTNIMGIV 120
  121 LCTQRAVRSM RERKFDGHVV LINSILGHKT MTATEGVAPD VNVYPPSKHA VTALAEGYRQ 180
  181 EFFGLGTRIK ITSVSPGVVD TEIVPDSIRE AIKDRMLHSE DIAQGVLYAI ATPPHVQVHE 240
  241 LIIKPLGETM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.69897
Match:	1xg5A
Description:	Structure of human putative dehydrogenase MGC4172 in complex with NADP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	3.09625241707629	bayes_pls_golite062009
retinol dehydrogenase activity	2.50453100919665	bayes_pls_golite062009
structural molecule activity	2.31813292180084	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	2.04225907952394	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	2.03461533859253	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	2.01043991420942	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
steroid dehydrogenase activity	1.75109362865449	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.65338499044318	bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.55012034958204	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47309297191111	bayes_pls_golite062009
fatty acid synthase activity	1.23679054027553	bayes_pls_golite062009
alcohol binding	1.07158175924364	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.01627645289834	bayes_pls_golite062009
binding	0.982999356179965	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	0.867909552357575	bayes_pls_golite062009
retinal dehydrogenase activity	0.69372321031969	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity	0.604742541607263	bayes_pls_golite062009
3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity	0.583772223704381	bayes_pls_golite062009
DNA binding	0.525227236870065	bayes_pls_golite062009
nucleic acid binding	0.459537641913493	bayes_pls_golite062009
retinol binding	0.343379136183648	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	0.311551606659739	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.258223964404048	bayes_pls_golite062009
transcription regulator activity	0.177044638410302	bayes_pls_golite062009
coenzyme binding	0.0812901552017963	bayes_pls_golite062009
ethanol binding	0.0448614072391299	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: