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Protein Overview: Xpac-PA

General Information:
Name(s) found: Xpac-PA / FBpp0070638 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene Xeroderma pigmentosum group A-like is referred to in FlyBase by the symbol Dmel\Xpac (CG6358, FBgn0004832). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3997047..3998230. It has the cytological map location 4A5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleotide binding; damaged DNA binding. There is experimental evidence that it is involved in the biological process</span>: nucleotide-excision repair. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 296 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    Biological Process: nucleotide-excision repair [IDA][IGI][ISS]
    Molecular Function: nucleotide binding [IEA]
    damaged DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAEVSTNES APPAEKKSKL TNAQKARIER NQAKAQKLRE AKLVSHPFKE LASNKEGGTH  60
   61 PEAALSQGSS VIKVQGTKYI DSGGGFLLEQ PVMPTGVGPA GLNKSGEEAP PILDDAIAIP 120
  121 VQYEECLECG DMFADSYLFN NFGHSVCDKC RDKDERYALI TRTEAKAEYL LKDCDFDKRE 180
  181 PKLRYISRKN PHNVRWGEMK LYLHLQIHQR ALEVWGSEEE LVRQHEARED KREEGKARKY 240
  241 NKKMKQLRME VRSSIYTKKT HEVHEHEFGP DTYDEEEDTY THTCITCPYS ETYEKM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..71] MSA 1.031989 View MSA. No confident structure predictions are available.
    2 View Details [72..296] PSI-BLAST 43.69897 SOLUTION STRUCTURE OF THE DNA-AND RPA-BINDING DOMAIN OF THE HUMAN REPAIR FACTOR XPA, NMR, 1 STRUCTURE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.96409924710655 bayes_pls_golite062009
  • protein binding
    		•  2.44501340584871 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.22839475692516 bayes_pls_golite062009
  • DNA binding
    		•  2.18702281581791 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.04270847321412 bayes_pls_golite062009
  • transcription activator activity
    		•  1.60639114794515 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.59705128803795 bayes_pls_golite062009
  • transcription factor activity
    		•  1.44182975349714 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.610805977602876 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
    		•  0.55799224325565 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.51536225088963 bayes_pls_golite062009
  • transcription factor binding
    		•  0.43597775400036 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.42962641193703 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.37925266318051 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.280685154942276 bayes_pls_golite062009
  • receptor activity
    		•  0.230063209127305 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.10722537662857 bayes_pls_golite062009
  • catalytic activity
    		•  0.101795606736461 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle