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Protein Overview: arg-PA

General Information:
Name(s) found: arg-PA / FBpp0070083 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • The gene arginase is referred to in FlyBase by the symbol Dmel\arg (CG18104, FBgn0023535). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:403451..422070. It has the cytological map location 1B7-1B8. Based on sequence similarity, it is predicted to have molecular function</span>: arginase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: arginine catabolic process to ornithine. 36 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 351 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [ISS]
    Biological Process: arginine catabolic process to ornithine [ISS]
    Molecular Function: metal ion binding [IEA]
    arginase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWWSRKFASR SLRLHRLKST GSTAPREPEQ SLGIIGVPFA KGQAKQGVEL APDLLRQSSL  60
   61 RQVLQSSHDG LVIRDYGNLQ YAVDEPLLQQ QRVHYHHIRN YADFMACNRA LIEQVKLMLV 120
  121 ENTQFLAIGG DHAIGFGSVA GHLQHTPNLS LVWIDAHADI NLHSTSQSGN IHGMPVSFLL 180
  181 EQLRNTWQHA GLQEIAPNCL PKDQLVYIGL RDIDPYEAFI LNKVGIRYYA MDTIDRVGVP 240
  241 KIIEMTLDAL NPQNKIHVSF DIDALDSNVA PSTGTAVRGG LTLREGISIV EALRDTKRVQ 300
  301 GVDLVEINPK LGSERDVRTT VESGLEILKS MFGYRRSGRW SNIDTGILGS D

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..351] PSI-BLAST 87.522879 Arginase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arginase activity
    		•  6.53441421234691 bayes_pls_golite062009
  • protein deacetylase activity
    		•  3.15425266272734 bayes_pls_golite062009
  • histone deacetylase activity
    		•  3.10913119405575 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.52770743634098 bayes_pls_golite062009
  • hydrolase activity
    		•  2.11707868768295 bayes_pls_golite062009
  • transcription factor binding
    		•  2.06538836131829 bayes_pls_golite062009
  • binding
    		•  1.948738669065 bayes_pls_golite062009
  • deacetylase activity
    		•  1.91016771390707 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.72243397396987 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.70671280294121 bayes_pls_golite062009
  • catalytic activity
    		•  1.68836803454021 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.59562744871718 bayes_pls_golite062009
  • DNA binding
    		•  1.55288325159263 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
    		•  1.01223037319069 bayes_pls_golite062009
  • transcription factor activity
    		•  0.882841288306625 bayes_pls_golite062009
  • protein binding
    		•  0.725535842743004 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.68008378742866 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.52929003055123 bayes_pls_golite062009
  • enzyme binding
    		•  0.39566582482721 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.38389503761392 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  0.0917282383800223 bayes_pls_golite062009
  • agmatinase activity
    		•  0.0741975192826536 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.79

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle