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Protein Overview: ase-PA

General Information:
Name(s) found: ase-PA / FBpp0070074 [FlyBase]
Description(s) found:
Found 29 descriptions.
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  • The gene asense is referred to in FlyBase by the symbol Dmel\ase (CG3258, FBgn0000137). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:354533..357209. It has the cytological map location 1B3. It is reported to have molecular function</span>: transcription factor activity; DNA binding; RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: nervous system development; bristle morphogenesis. 15 alleles are reported. The phenotypes of these alleles are annotated with: sense organ; sensory mother cell; microchaeta; macrochaeta; external sensory organ. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 486 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA][NAS]
    Biological Process: bristle morphogenesis [IMP]
    central nervous system development [NAS]
    nervous system development [IGI]
    neuroblast fate determination [NAS]
    regulation of transcription, DNA-dependent [NAS]
    peripheral nervous system development [NAS]
    regulation of transcription [IEA]
    Molecular Function: DNA binding [IEA][NAS]
    transcription factor activity [NAS]
    RNA polymerase II transcription factor activity [NAS]
    transcription regulator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALSFSPSP PPKENPKENP NPGIKTTLKP FGKITVHNVL SESGANALQQ HIANQNTIIR  60
   61 KIRDFGMLGA VQSAAASTTN TTPISSQRKR PLGESQKQNR HNQQNQQLSK TSVPAKKCKT 120
  121 NKKLAVERPP KAGTISHPHK SQSDQSFGTP GRKGLPLPQA VARRNARERN RVKQVNNGFA 180
  181 LLREKIPEEV SEAFEAQGAG RGASKKLSKV ETLRMAVEYI RSLEKLLGFD FPPLNSQGNS 240
  241 SGSGDDSFMF IKDEFDCLDE HFDDSLSNYE MDEQQTVQQT LSEDMLNPPQ ASDLLPSLTT 300
  301 LNGLQYIRIP GTNTYQLLTT DLLGDLSHEQ KLEETAASGQ LSRSPVPQKV VRSPCSSPVS 360
  361 PVASTELLLQ TQTCATPLQQ QVIKQEYVST NISSSSNAQT SPQQQQQVQN LGSSPILPAF 420
  421 YDQEPVSFYD NVVLPGFKKE FSDILQQDQP NNTTAGCLSD ESMIDAIDWW EAHAPKSNGA 480
  481 CTNLSV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] deduced N/A No confident structure predictions are available.
    2 View Details [135..245] PSI-BLAST 9.0 Max protein
    3 View Details [246..486] MSA 13.158997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.38658950816179 bayes_pls_golite062009
  • DNA binding
    		•  5.18654839258297 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.05768805749761 bayes_pls_golite062009
  • transcription factor activity
    		•  4.78039531631248 bayes_pls_golite062009
  • binding
    		•  3.81829206350975 bayes_pls_golite062009
  • transcription factor binding
    		•  2.61163564741984 bayes_pls_golite062009
  • transcription activator activity
    		•  2.5495467409976 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.48787404513864 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.31910036997977 bayes_pls_golite062009
  • protein binding
    		•  1.59929864805879 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.52770895937238 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  1.46304579811572 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.955588849035129 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.801830750183111 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.3513586903977 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle