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View Structure Prediction Details

Protein: ase-PA
Organism: Drosophila melanogaster
Length: 486 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ase-PA.

Description E-value Query
Range
Subject
Range
gi|3618329 - gi|3618329|dbj|BAA33209.1| asense [Drosophila yakuba]
281.0 [0..1] [486..1]

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Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALSFSPSP PPKENPKENP NPGIKTTLKP FGKITVHNVL SESGANALQQ HIANQNTIIR  60
   61 KIRDFGMLGA VQSAAASTTN TTPISSQRKR PLGESQKQNR HNQQNQQLSK TSVPAKKCKT 120
  121 NKKLAVERPP KAGT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [135-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISHPHKSQSD QSFGTPGRKG LPLPQAVARR NARERNRVKQ VNNGFALLRE KIPEEVSEAF  60
   61 EAQGAGRGAS KKLSKVETLR MAVEYIRSLE KLLGFDFPPL NSQGNSSGSG D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.0
Match: 1hloA
Description: Max protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
transcription activator activity 2.5495467409976 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.48787404513864 bayes_pls_golite062009
sequence-specific DNA binding 2.31910036997977 bayes_pls_golite062009
protein binding 1.59929864805879 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 1.46304579811572 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [246-486]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSFMFIKDEF DCLDEHFDDS LSNYEMDEQQ TVQQTLSEDM LNPPQASDLL PSLTTLNGLQ  60
   61 YIRIPGTNTY QLLTTDLLGD LSHEQKLEET AASGQLSRSP VPQKVVRSPC SSPVSPVAST 120
  121 ELLLQTQTCA TPLQQQVIKQ EYVSTNISSS SNAQTSPQQQ QQVQNLGSSP ILPAFYDQEP 180
  181 VSFYDNVVLP GFKKEFSDIL QQDQPNNTTA GCLSDESMID AIDWWEAHAP KSNGACTNLS 240
  241 V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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