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Protein Overview: FBpp0312057, Jon...

General Information:
Name(s) found: FBpp0312057 [FlyBase]
Jon99Cii-PA / FBpp0084878 [FlyBase]
Jon99Ciii-PA / FBpp0084868 [FlyBase]
Description(s) found:
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  • gi|7301863|gb|AAF56972.1| jonah 99Cii [Drosophila melanogaster] [NCBI NR]
  • pir||A38894 serine proteinase (EC 3.4.21.-) 2 precursor - fruit fly (Drosophila melanogaster) [NCBI NR]
  • gi|455164|gb|AAB02553.1| serine protease 2 [NCBI NR]
  • gi|24651216|ref|NP_733330.1| jonah 99Ciii [Drosophila melanogaster] [NCBI NR]
  • gi|23172627|gb|AAN14201.1| jonah 99Ciii [Drosophila melanogaster] [NCBI NR]
  • gi|18079291|ref|NP_524554.1| jonah 99Cii [Drosophila melanogaster] [NCBI NR]
  • gi|12644134|sp|P17205.2|SER1_DROME RecName: Full=Serine proteases 1/2; AltName: Full=Protein Jonah 99Cii/99Ciii; Flags: Precursor [NCBI NR]
  • Serine proteases 1/2 OS=Drosophila melanogaster GN=Jon99Cii PE=2 SV=2 [Swiss-Prot]
  • type=protein; loc=3R:25747964..25748761; ID=FBpp0312057; name=Jon99Ciii-PB; parent=FBgn0003357,FBtr0346340; dbxref=FlyBase:FBpp0312057,FlyBase_Annotation_IDs:CG31362-PB; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r5.56; species=Dmel; [FlyBase]
  • The gene Jonah 99Cii is referred to in FlyBase by the symbol Dmel\Jon99Cii (CG31034, FBgn0003356). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25749476..25750333. It has the cytological map location 99C7. Based on sequence similarity, it is predicted to have molecular function</span>: serine-type endopeptidase activity. It is reported to be involved in the biological process</span>: digestion; proteolysis. No alleles are reported. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • The gene Jonah 99Ciii is referred to in FlyBase by the symbol Dmel\Jon99Ciii (CG31362, FBgn0003357). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25747931..25748823. It has the cytological map location 99C7. It is reported to have molecular function</span>: serine-type peptidase activity; serine-type endopeptidase activity. It is reported to be involved in the biological process</span>: digestion; proteolysis. No alleles are reported. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG31362-PA translation from_gene[CG31362 Ser99Db FBgn0003357] seq_release:3 mol_weight=28469 cds_boundaries:(3R:25,737,330..25,738,124[+]) aa_length:265 transcript_info:[CG31362-RA seq_release:3] gene_info:[gene symbol:Ser99Db synonyms:[CG15519] FBgn0 [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG31034-PA translation from_gene[CG31034 Ser99Da FBgn0003356] seq_release:3 mol_weight=28469 cds_boundaries:(3R:25,738,881..25,739,675[-]) aa_length:265 transcript_info:[CG31034-RA seq_release:3] gene_info:[gene symbol:Ser99Da synonyms:[CG7877] FBgn00 [hmr_yeast5_DM3-1_pombe.fasta]
  • (P17205) Serine proteases 1/2 precursor (EC 3.4.21.-) [DrosMelano7227.FASTAC.txt]
  • (AE003771) Ser99Da gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG31034-PA [Drosophila melanogaster]gi|23172627|gb|AAN14201.1| CG31362-PA [Drosophila melanogaster]gi|24651216|ref|NP_733330.1| CG31362-PA [Drosophila melanogaster]gi|18079291|ref|NP_524554.1| CG31034-PA [Drosophila melanogaster]gi|455164|gb|AAB02553. [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(25749512..25750309); ID=FBpp0084878; name=Jon99Cii-PA; parent=FBgn0003356,FBtr0085512; dbxref=FlyBase:FBpp0084878,FlyBase_Annotation_IDs:CG31034-PA,GB_protein:AAF56972.1,REFSEQ:NP_524554,GB_protein:AAF56972; MD5=1e2effa48fa [fly-100309-contam.fasta]
  • type=protein; loc=3R:25747964..25748761; ID=FBpp0084868; name=Jon99Ciii-PA; parent=FBgn0003357,FBtr0085502; dbxref=FlyBase:FBpp0084868,FlyBase_Annotation_IDs:CG31362-PA,GB_protein:AAN14201.1,REFSEQ:NP_733330,GB_protein:AAN14201; MD5=1e2effa48fa812e3aa6d92 [fly-100309-contam.fasta]
  • CG31034-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Jonah 99Cii CG31034-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG31362-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Serine proteases 1/2 precursor (Protein Jonah 99Cii/99Ciii) [nr-271106-contam.fasta]
  • serine protease 2 [nr-271106-contam.fasta]
  • Jonah 99Ciii CG31362-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(25749512..25750309); ID=FBpp0084878; name=Jon99Cii-PA; parent=FBgn0003356,FBtr0085512; dbxref=FlyBase:FBpp0084878,FlyBase_Annotation_IDs:CG31034-PA,GB_protein:AAF56972.1,REFSEQ:NP_524554,GB_protein:AAF56972; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:25747964..25748761; ID=FBpp0084868; name=Jon99Ciii-PA; parent=FBgn0003357,FBtr0085502; dbxref=FlyBase:FBpp0084868,FlyBase_Annotation_IDs:CG31362-PA,GB_protein:AAN14201.1,REFSEQ:NP_733330,GB_protein:AAN14201; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(25749512..25750309); ID=FBpp0084878; name=Jon99Cii-PA; parent=FBgn0003356,FBtr0085512; dbxref=FlyBase:FBpp0084878,FlyBase_Annotation_IDs:CG31034-PA,GB_protein:AAF56972.1,REFSEQ:NP_524554,GB_protein:AAF56972; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:25747964..25748761; ID=FBpp0084868; name=Jon99Ciii-PA; parent=FBgn0003357,FBtr0085502; dbxref=FlyBase:FBpp0084868,FlyBase_Annotation_IDs:CG31362-PA,GB_protein:AAN14201.1,REFSEQ:NP_733330,GB_protein:AAN14201; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Serine proteases 1/2 OS=Drosophila melanogaster GN=Jon99Cii PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:25747964..25748761; ID=FBpp0084868; name=Jon99Ciii-PA; parent=FBgn0003357,FBtr0085502; dbxref=FlyBase:FBpp0084868,FlyBase_Annotation_IDs:CG31362-PA,GB_protein:AAN14201.1,REFSEQ:NP_733330,GB_protein:AAN14201; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(25749512..25750309); ID=FBpp0084878; name=Jon99Cii-PA; parent=FBgn0003356,FBtr0085512; dbxref=FlyBase:FBpp0084878,FlyBase_Annotation_IDs:CG31034-PA,GB_protein:AAF56972.1,REFSEQ:NP_524554,GB_protein:AAF56972,FlyMine:FBpp0084878,modMine:FBpp0084878; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(29923790..29924587); ID=FBpp0084878; name=Jon99Cii-PA; parent=FBgn0003356,FBtr0085512; dbxref=FlyBase:FBpp0084878,FlyBase_Annotation_IDs:CG31034-PA,GB_protein:AAF56972.1,REFSEQ:NP_524554,GB_protein:AAF56972,FlyMine:FBpp0084878,modMine:FBpp0084878; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:29922242..29923039; ID=FBpp0084868; name=Jon99Ciii-PA; parent=FBgn0003357,FBtr0085502; dbxref=FlyBase:FBpp0084868,FlyBase_Annotation_IDs:CG31362-PA,GB_protein:AAN14201.1,REFSEQ:NP_733330,GB_protein:AAN14201; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:29922242..29923039; ID=FBpp0312057; name=Jon99Ciii-PB; parent=FBgn0003357,FBtr0346340; dbxref=FlyBase:FBpp0312057,FlyBase_Annotation_IDs:CG31362-PB,GB_protein:AHN57597,REFSEQ:NP_001287598; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(29923790..29924587); ID=FBpp0084878; name=Jon99Cii-PA; parent=FBgn0003356,FBtr0085512; dbxref=FlyBase:FBpp0084878,FlyBase_Annotation_IDs:CG31034-PA,GB_protein:AAF56972.1,REFSEQ:NP_524554,GB_protein:AAF56972,FlyMine:FBpp0084878,modMine:FBpp0084878; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:29922242..29923039; ID=FBpp0084868; name=Jon99Ciii-PA; parent=FBgn0003357,FBtr0085502; dbxref=FlyBase:FBpp0084868,FlyBase_Annotation_IDs:CG31362-PA,GB_protein:AAN14201.1,REFSEQ:NP_733330,GB_protein:AAN14201; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:29922242..29923039; ID=FBpp0312057; name=Jon99Ciii-PB; parent=FBgn0003357,FBtr0346340; dbxref=FlyBase:FBpp0312057,FlyBase_Annotation_IDs:CG31362-PB,GB_protein:AHN57597,REFSEQ:NP_001287598; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of P17205, Jonah 99Ciii, isoform B OS=Drosophila melanogaster GN=Jon99Ciii PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0084878 type=protein; loc=3R:complement(29923790..29924587); ID=FBpp0084878; name=Jon99Cii-PA; parent=FBgn0003356,FBtr0085512; dbxref=FlyBase:FBpp0084878,FlyBase_Annotation_IDs:CG31034-PA,GB_protein:AAF56972.1,REFSEQ:NP_524554,GB_protein:AAF56972,FlyMine:FBpp0084878,modMine:FBpp0084878; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0084868 type=protein; loc=3R:29922242..29923039; ID=FBpp0084868; name=Jon99Ciii-PA; parent=FBgn0003357,FBtr0085502; dbxref=FlyBase:FBpp0084868,FlyBase_Annotation_IDs:CG31362-PA,GB_protein:AAN14201.1,REFSEQ:NP_733330,GB_protein:AAN14201; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0312057 type=protein; loc=3R:29922242..29923039; ID=FBpp0312057; name=Jon99Ciii-PB; parent=FBgn0003357,FBtr0346340; dbxref=FlyBase:FBpp0312057,FlyBase_Annotation_IDs:CG31362-PB,GB_protein:AHN57597,REFSEQ:NP_001287598; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:29922242..29923039; ID=FBpp0084868; name=Jon99Ciii-PA; parent=FBgn0003357,FBtr0085502; dbxref=FlyBase:FBpp0084868,FlyBase_Annotation_IDs:CG31362-PA,GB_protein:AAN14201.1,REFSEQ:NP_733330,GB_protein:AAN14201,UniProt/Swiss-Prot:P17205; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:29922242..29923039; ID=FBpp0312057; name=Jon99Ciii-PB; parent=FBgn0003357,FBtr0346340; dbxref=FlyBase:FBpp0312057,FlyBase_Annotation_IDs:CG31362-PB,GB_protein:AHN57597,REFSEQ:NP_001287598,UniProt/Swiss-Prot:P17205; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:complement(29923790..29924587); ID=FBpp0084878; name=Jon99Cii-PA; parent=FBgn0003356,FBtr0085512; dbxref=FlyBase:FBpp0084878,FlyBase_Annotation_IDs:CG31034-PA,GB_protein:AAF56972.1,REFSEQ:NP_524554,GB_protein:AAF56972,UniProt/Swiss-Prot:P17205,FlyMine:FBpp0084878,modMine:FBpp0084878; MD5=1e2effa48fa812e3aa6d92a4da9867ca; length=265; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 265 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEA][NAS]
    digestion [NAS]
    Molecular Function: serine-type peptidase activity [NAS]
    serine-type endopeptidase activity [IEA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLFVFLALA VAAATAVPAP AQKLTPTPIK DIQGRITNGY PAYEGKVPYI VGLLFSGNGN  60
   61 WWCGGSIIGN TWVLTAAHCT NGASGVTINY GASIRTQPQY THWVGSGDII QHHHYNSGNL 120
  121 HNDISLIRTP HVDFWSLVNK VELPSYNDRY QDYAGWWAVA SGWGGTYDGS PLPDWLQSVD 180
  181 VQIISQSDCS RTWSLHDNMI CINTDGGKST CGGDSGGPLV THDGNRLVGV TSFGSAAGCQ 240
  241 SGAPAVFSRV TGYLDWIRDN TGISY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..265] PSI-BLAST 61.0 Trypsin(ogen)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  5.91209560688646 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  5.52773635813967 bayes_pls_golite062009
  • serine hydrolase activity
    		•  5.5105092190926 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  5.49703869306079 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  5.39623690248556 bayes_pls_golite062009
  • endopeptidase activity
    		•  5.32070018460528 bayes_pls_golite062009
  • hydrolase activity
    		•  4.40346950809697 bayes_pls_golite062009
  • catalytic activity
    		•  1.40927913545237 bayes_pls_golite062009
  • binding
    		•  1.30738106455622 bayes_pls_golite062009
  • protein binding
    		•  1.30414885212044 bayes_pls_golite062009
  • fucose binding
    		•  1.28001086938735 bayes_pls_golite062009
  • calcium-dependent protein binding
    		•  1.10244132298625 bayes_pls_golite062009
  • heparin binding
    		•  1.0321632468756 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.03130756227487 bayes_pls_golite062009
  • growth factor activity
    		•  0.848900101748605 bayes_pls_golite062009
  • receptor binding
    		•  0.79054390509229 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.56945513804111 bayes_pls_golite062009
  • DNA binding
    		•  0.559109234340392 bayes_pls_golite062009
  • thrombospondin receptor activity
    		•  0.126941350425071 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.0828866805581887 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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