General Information: |
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Name(s) found: |
FBpp0300849
[FlyBase]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Drosophila melanogaster |
Length: | 1851 amino acids |
Gene Ontology: |
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Cellular Component: |
apicolateral plasma membrane
[IDA]
lateral plasma membrane [IDA] subapical complex [TAS] cytoplasm [NAS] septate junction [IDA][NAS][TAS] neuromuscular junction [IDA] basolateral plasma membrane [TAS] |
Biological Process: |
cell proliferation
[IMP]
dorsal closure [IMP][TAS] establishment or maintenance of apical/basal cell polarity [IMP] wing disc morphogenesis [IMP] negative regulation of cell proliferation [TAS] positive regulation of antibacterial peptide biosynthetic process [IMP] asymmetric protein localization [IMP][TAS] establishment or maintenance of epithelial cell apical/basal polarity [NAS][TAS] negative regulation of imaginal disc growth [IMP] morphogenesis of embryonic epithelium [TAS] establishment or maintenance of polarity of embryonic epithelium [TAS] regulation of cell cycle [NAS] morphogenesis of follicular epithelium [IMP] establishment or maintenance of polarity of follicular epithelium [IMP] morphogenesis of larval imaginal disc epithelium [IMP] establishment or maintenance of polarity of larval imaginal disc epithelium [IMP] pole cell migration [NAS] cell morphogenesis [IMP] response to chemical stimulus [IMP] establishment of ommatidial planar polarity [IMP] R3/R4 cell fate commitment [IMP] olfactory behavior [IMP] compound eye development [IMP] gonad development [NAS] zonula adherens assembly [IMP][TAS] septate junction assembly [IMP] negative regulation of epithelial cell proliferation [IMP] regulation of synapse structure and activity [IMP] establishment of imaginal disc-derived wing hair orientation [IMP] morphogenesis of a polarized epithelium [TAS] |
Molecular Function: |
protein binding
[IPI][ISS]
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Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MFKCIPIFKG CNRQVEFVDK RHCSLPQVPE EILRYSRTLE ELFLDANHIR DLPKNFFRLH 60 61 RLRKLGLSDN EIGRLPPDIQ NFENLVELDV SRNDIPDIPD DIKHLQSLQV ADFSSNPIPK 120 121 LPSGFSQLKN LTVLGLNDMS LTTLPADFGS LTQLESLELR ENLLKHLPET ISQLTKLKRL 180 181 DLGDNEIEDL PPYLGYLPGL HELWLDHNQL QRLPPELGLL TKLTYLDVSE NRLEELPNEI 240 241 SGLVSLTDLD LAQNLLEALP DGIAKLSRLT ILKLDQNRLQ RLNDTLGNCE NMQELILTEN 300 301 FLSELPASIG QMTKLNNLNV DRNALEYLPL EIGQCANLGV LSLRDNKLKK LPPELGNCTV 360 361 LHVLDVSGNQ LLYLPYSLVN LQLKAVWLSE NQSQPLLTFQ PDTDAETGEQ VLSCYLLPQQ 420 421 EYQPITPARD LESDSEPFEE REPSRTVVKF SEEATQEKET PFVRQNTPHP KDLKAKAQKL 480 481 KVERSRNEEH ANLVTLPEEN GTKLAETPTE TRTIANNHQQ QPHPVQQPIV GVNSKQPVVV 540 541 GVVTPTTTTV APTGVQGGSE GASSTANNVK AATAAVVAEL AATVGGSDEV QDDDEQEDEF 600 601 ESDRRVGFQV EGEDDDFYKR PPKLHRRDTP HHLKNKRVQH LTDKQASEIL ANALASQERN 660 661 DTTPQHSLSG KVTSPIEEEE QLEVEQEQQQ QQQQHPFDSS LSPISAGKTA EASTDPDNLD 720 721 GVTELRLEQY EIHIERTAAG LGLSIAGGKG STPFKGDDDG IFISRVTEAG PADLAGLKVG 780 781 DKVIKVNGIV VVDADHYQAV QVLKACGAVL VLVVQREVTR LIGHPVFSED GSVSQISVET 840 841 RPLVADAPPA ASISHERYIP APIEIVPQQQ HLQQQQQQPI QQVAPTHSYS GNVFATPTAA 900 901 QTVQPAVSAA PNGLLLNGRE APLSYIQLHT TLIRDQIGQG LGFSIAGGKG SPPFKDDCDG 960 961 IFISRITEGG LAYRDGKIMV GDRVMAINGN DMTEAHHDAA VACLTEPQRF VRLVLQREYR1020 1021 GPLEPPTSPR SPAVLNSLSP SGYLANRPAN FSRSVVEVEQ PYKYNTLATT TPTPKPTVPA1080 1081 SISNNNNTLP SSKTNGFATA AAATIDSSTG QPVPAPRRTN SVPMGDGDIG AGSTTSGDSG1140 1141 EAQPSSLRPL TSDDFQAMIP AHFLSGGSQH QVHVARPNEV GVSAVTVNVN KPQPDLPMFP1200 1201 AAPTELGRVT ETITKSTFTE TVMTRITDNQ LAEPLISEEV VLPKNQGSLG FSIIGGTDHS1260 1261 CVPFGTREPG IFISHIVPGG IASKCGKLRM GDRILKVNEA DVSKATHQDA VLELLKPGDE1320 1321 IKLTIQHDPL PPGFQEVLLS KAEGERLGMH IKGGLNGQRG NPADPSDEGV FVSKINSVGA1380 1381 ARRDGRLKVG MRLLEVNGHS LLGASHQDAV NVLRNAGNEI QLVVCKGYDK SNLIHSIGQA1440 1441 GGMSTGFNSS ASCSGGSRQG SRASETGSEL SQSQSVSSLD HEEDERLRQD FDVFASQKPD1500 1501 AQQPTGPSVL AAAAAMVHGA SSPTPPAATS NITPLPTAAA VASADLTAPD TPATQTVALI1560 1561 HAEQQAHQQQ QQTQLAPLGQ EKSTQEKVLE IVRAADAFTT VPPKSPSEHH EQDKIQKTTT1620 1621 VVISKHTLDT NPTTPTTPAA PLSIAGAESA NSAGAPSPAV PASTPGSAPV LPAVAVQTQT1680 1681 QTTSTEKDEE EESQLQSTPA SRDGAEEQQE EVRAKPTPTK VPKSVSDKKR FFESAMEDQH1740 1741 KPTQKTDKVF SFLSKDEVEK LRQEEERKIA TLRRDKNSRL LDAANDNIDK DAAQQRTKSN1800 1801 SNSSSGDDND DSDQEEGIAR GDSVDNAALG HFDDAEDMRN PLDEIEAVFR S |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Domains predicted:
# | Region(s) | Method | Confidence | Match Description | |
1 | View Details | [1..640] | ![]() |
70.045757 | The molecular structure of toll-like receptor 3 ligand binding domain |
2 | View Details | [641..714] | ![]() |
N/A | No confident structure predictions are available. |
3 | View Details | [715..821] | ![]() |
15.154902 | Na+/H+ exchanger regulatory factor, NHERF |
4 | View Details | [822..926] | ![]() |
N/A | No confident structure predictions are available. |
5 | View Details | [927..1030] | ![]() |
23.0 | Solution structure of the first PDZ domain of scribble homolog protein (hScrib) |
6 | View Details | [1031..1116] | ![]() |
N/A | No confident structure predictions are available. |
7 | View Details | [1117..1231] | ![]() |
25.0 | Structural Insights into the Inter-domain Chaperoning of Tandem PDZ Domains in Glutamate Receptor Interacting Proteins |
8 | View Details | [1232..1330] | ![]() |
4.83 | Solution structure of the alternatively spliced PDZ2 domain (PDZ2b) of PTP-Bas (hPTP1E) |
9 | View Details | [1331..1428] | ![]() |
21.39794 | Solution structure of the fourth PDZ domain of human scribble (KIAA0147 protein) |
10 | View Details | [1429..1611] | ![]() |
N/A | No confident structure predictions are available. |
11 | View Details | [1612..1851] | ![]() |
1.136996 | View MSA. No confident structure predictions are available. |
Functions predicted (by domain):
# | Gene Ontology predictions | |||||||||||||||||||||||||||||||||||||||||||||||||||
1 | No functions predicted. | |||||||||||||||||||||||||||||||||||||||||||||||||||
2 | No functions predicted. | |||||||||||||||||||||||||||||||||||||||||||||||||||
3 |
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4 | No functions predicted. | |||||||||||||||||||||||||||||||||||||||||||||||||||
5 |
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6 | No functions predicted. | |||||||||||||||||||||||||||||||||||||||||||||||||||
7 |
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8 |
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9 |
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10 | No functions predicted. | |||||||||||||||||||||||||||||||||||||||||||||||||||
11 | No functions predicted. |
Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)