Protein Overview: gi|24650134, gi|...

General Information:
Name(s) found:	gi\|24650134 [NCBI NR] gi\|23172322 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|24650134\|ref\|NP_733119.1\| LpR1, isoform A [Drosophila melanogaster] [NCBI NR] gi\|23172322\|gb\|AAF56499.2\| LpR1, isoform A [Drosophila melanogaster] [NCBI NR] >CG4861-PA translation from_gene[CG4861 CG4861 FBgn0039363] seq_release:3 mol_weight=98320 cds_boundaries:(3R:21,557,070..21,567,229[-]) aa_length:883 transcript_info:[CG4861-RA seq_release:3] gene_info:[gene symbol:CG4861 FLAGGED_PROBLEMATIC FBgn00393 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VBN1) CG31094-PA [DrosMelano7227.FASTAC.txt] CG31094-PA, isoform A [Drosophila melanogaster]gi\|24650134\|ref\|NP_733119.1\| CG31094-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3R:complement(21567702..21567734,21567876..21568037,21568114..21568247,21570088..21570246,21570406..21570604,21570702..21572114,21572729..21572955,21573825..21573947,21574992..21575111,21577783..21577864); ID=FBpp0084299; name=LpR1-PA; p [fly-100309-contam.fasta] LpR1 CG31094-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] CG31094-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3R:complement(21567702..21567734,21567876..21568037,21568114..21568247,21570088..21570246,21570406..21570604,21570702..21572114,21572729..21572955,21573825..21573947,21574992..21575111,21577783..21577864); ID=FBpp0084299; name=LpR1-PA; parent=FBgn0066101,FBtr0084925; dbxref=FlyBase:FBpp0084299,FlyBase_Annotation_IDs:CG31094-PA,GB_protein:AAF56499.2,REFSEQ:NP_733119,GB_protein:AAF56499; MD5=1670210572b1717493d1704cc12833df; length=883; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
Organism:	Drosophila melanogaster
Length:	883 amino acids
Gene Ontology:
Cellular Component:	membrane [ISS]
Biological Process:	cholesterol metabolic process [ISS] receptor-mediated endocytosis [IEP][IMP] lipoprotein transport [ISS]
Molecular Function:	lipoprotein binding [ISS] calcium ion binding [IEA] low-density lipoprotein receptor activity [ISS] receptor activity [IEP][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRIWCLLFV SSLLHTQSQS FRVLAINEAT CSSDQFRCGN GNCIPNKWRC DQESDCADGS  60
   61 DEANELCRAR TCSPDEYACK SGEGQCVPLA WMCDQSKDCS DGSDEHNCNQ TCRADEFTCG 120
  121 NGRCIQKRWK CDHDDDCGDG SDEKECPVVP CDSVAEHTCT NGACIAKRWV CDGDPDCSDG 180
  181 SDERSCANVT KTTTPCLSHE YQCKDRITCL HHSWLCDGDR DCPDGDDEHT ANCKNVTCRA 240
  241 DQFQCGDRSC IPGHLTCNGD KDCADGSDER DCGLSLSLGI NQGGCNATSE FDCGGGQCVP 300
  301 LSKVCDKRKD CPDGEDEPAG KCGINECASK NGGCMHQCID LKVGHHCECH EGYKLSPDKR 360
  361 NCQDINECEV PGKCSQICVN EIGGFKCECE AGYMRDPKNH TRCKASEGHA SLLLARRHDI 420
  421 RKIALDHMEM TSIVNSTKAA TALDFVFRTG MIFWSDVTTQ SIYKAPIDEG NEKTVVLTKS 480
  481 SVTSDGLAVD WIYNHVYFTD THKCTIELTN FEGSMGKVLV KDSLDIPRSI ALDPIEGWMY 540
  541 WSDWGASPRI ERAGMDGSHR TTIISYDVKW PNGITLDLVK KRIYWVDGKL NVISSANYDG 600
  601 SQRSQVLYSG EYLRHPFSIT TFEDNVYWTD WDKQAVFKAN KFTGEDVEPV TAMHMLQHPM 660
  661 VVHVYHPYRQ PDGVNHCQSV NGHCSHLCLP APRINERSPR ISCACPTGLK LMVDGLMCVE 720
  721 DLTRPPRARK TKPRPKSPRR RLPTGVQVGH ADIRIEINDD LQLSTRLPLL PTTFVADQRP 780
  781 VKNHTQIEKT TTPSEQPDSG FIALVVIASL SGFAVLLSVL LLIGYRYCSK RRINSMNFEN 840
  841 PIYRKTTTTE DHFSLRKNLP ARIYDHTSVM DEEYSPVIGI SSY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
very-low-density lipoprotein receptor activity	7.75680908341624	bayes_pls_golite062009
very-low-density lipoprotein binding	7.75680908341624	bayes_pls_golite062009
low-density lipoprotein binding	6.26591728596226	bayes_pls_golite062009
receptor activity	5.18957329214193	bayes_pls_golite062009
transmembrane receptor activity	5.12821337870369	bayes_pls_golite062009
molecular transducer activity	4.28859337937742	bayes_pls_golite062009
signal transducer activity	4.28859337937742	bayes_pls_golite062009
lipoprotein binding	4.14588039269064	bayes_pls_golite062009
ErbB-2 class receptor binding	4.1172010378646	bayes_pls_golite062009
low-density lipoprotein receptor activity	3.65371958920557	bayes_pls_golite062009
lipoprotein receptor binding	3.5371428063122	bayes_pls_golite062009
ErbB-3 class receptor binding	3.52219710022937	bayes_pls_golite062009
lipoprotein receptor activity	3.27342368855237	bayes_pls_golite062009
apolipoprotein binding	3.15697162337516	bayes_pls_golite062009
binding	3.10919144943954	bayes_pls_golite062009
glycosaminoglycan binding	2.86713236325679	bayes_pls_golite062009
heparin binding	2.49012176521764	bayes_pls_golite062009
polysaccharide binding	2.16901652361989	bayes_pls_golite062009
transcription regulator activity	2.16844098063599	bayes_pls_golite062009
sterol transporter activity	2.16184949636569	bayes_pls_golite062009
apolipoprotein E binding	2.15688766106363	bayes_pls_golite062009
protein binding	2.11668700345827	bayes_pls_golite062009
receptor binding	2.00382722979859	bayes_pls_golite062009
lipid transporter activity	1.91872326766441	bayes_pls_golite062009
lipoprotein transporter activity	1.72944996169507	bayes_pls_golite062009
transcription factor binding	1.71838409809333	bayes_pls_golite062009
transcription cofactor activity	1.61057978332614	bayes_pls_golite062009
high-density lipoprotein binding	1.52515316728946	bayes_pls_golite062009
growth factor activity	1.52153421000803	bayes_pls_golite062009
transporter activity	1.44005597324471	bayes_pls_golite062009
collagen binding	1.3611207932336	bayes_pls_golite062009
protein transporter activity	1.27232657510644	bayes_pls_golite062009
pattern binding	1.26957983931218	bayes_pls_golite062009
substrate-specific transporter activity	1.08803800589535	bayes_pls_golite062009
protein kinase activity	1.00235965838736	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.741912411452008	bayes_pls_golite062009
carbohydrate binding	0.72748768329894	bayes_pls_golite062009
kinase activity	0.692244195382463	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.67022333774569	bayes_pls_golite062009
extracellular matrix structural constituent	0.66981956037474	bayes_pls_golite062009
cell adhesion molecule binding	0.44857826904729	bayes_pls_golite062009
extracellular matrix binding	0.3265100728106	bayes_pls_golite062009

No functions predicted.

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..796]	PSI-BLAST	131.0	Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
2	View Details	[797..883]	deduced	N/A	No confident structure predictions are available.

Protein Overview: gi|24650134, gi|...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: