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Protein Overview: FBpp0306564, CG6...

General Information:
Name(s) found: FBpp0306564 [FlyBase]
CG6763-PA / FBpp0083770 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=3R:join(19110496..19111317,19111384..19111626); ID=FBpp0306564; name=CG6763-PB; parent=FBgn0039069,FBtr0334497; dbxref=FlyBase:FBpp0306564,FlyBase_Annotation_IDs:CG6763-PB,REFSEQ:NP_001262871,GB_protein:AGB96251; MD5=424684e7d6ec3046ff7357480e2e4222; length=354; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG6763 (CG6763, FBgn0039069). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19109724..19111763. It has the cytological map location 94E9. Based on sequence similarity, it is predicted to have molecular function</span>: metalloendopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 354 amino acids

    Gene Ontology:
    Cellular Component: meprin A complex [ISS]
    Biological Process: proteolysis [IEA]
    Molecular Function: zinc ion binding [IEA]
    metalloendopeptidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKVFLVLA LALSSCQALP YVSYDDVDDT EVIELPGNGI EEIPPTLGKD IIDLTPLGTA  60
   61 LFGKPDEELT ANRVGNFSAD ADEMNPEELG SYLEGDMLVP QTDLIMKNGL PTQSSRWPNG 120
  121 VVPYEIRGNF NARDMATIEN AIGEYHRRTC IRFVKRSSER DYISIRGDNS GCWSSVGRVG 180
  181 GKQEVNLQSP GCLSRPGTAM HELMHALGFL HEQNRMERDG YVAIQYNNVQ SSAMNNFEKA 240
  241 ARTEAFGVPY DYGSVMHYSK NAFSINGQPT ILAMQANGAD KMGQRNGFSD YDIQKLNRMY 300
  301 DCGTVNAVPV APGLPAPAPA PGAPAGSGNP IVDSFIGGLI SGLGLGDEKK ETSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..251] PSI-BLAST 25.39794 CRYSTAL STRUCTURE OF FIBROBLAST STROMELYSIN-1: THE C-TRUNCATED HUMAN PROENZYME
    2 View Details [252..354] PSI-BLAST 49.09691 STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  4.1917763812737 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  3.85190688399485 bayes_pls_golite062009
  • metallopeptidase activity
    		•  3.22757426039234 bayes_pls_golite062009
  • endopeptidase activity
    		•  2.98133341931091 bayes_pls_golite062009
  • hydrolase activity
    		•  2.78513171530601 bayes_pls_golite062009
  • metalloendopeptidase activity
    		•  2.54952091441017 bayes_pls_golite062009
  • transporter activity
    		•  1.28982382930122 bayes_pls_golite062009
  • binding
    		•  1.19918194301835 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.0688261398267 bayes_pls_golite062009
  • catalytic activity
    		•  0.891187593353827 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.798767221679673 bayes_pls_golite062009
  • protein binding
    		•  0.738116106084931 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.543737159152136 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.492456025063956 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.241890854867053 bayes_pls_golite062009
  • integrin binding
    		•  0.0945964646680701 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.00533877867882504 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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