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Protein Overview: sar1-PB

General Information:
Name(s) found: sar1-PB / FBpp0083605 [FlyBase]
Description(s) found:
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  • gi|23176037|gb|AAN14371.1| sar1, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|21355813|ref|NP_651025.1| sar1, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|16648394|gb|AAL25462.1| LD39266p [Drosophila melanogaster] [NCBI NR]
  • The gene sar1 is referred to in FlyBase by the symbol Dmel\sar1 (CG7073, FBgn0038947). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18182397..18186440. It has the cytological map location 94A5-94A6. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity; GTP binding. There is experimental evidence that it is involved in the biological process</span>: chitin-based larval cuticle pattern formation; negative regulation of dendrite morphogenesis; larval chitin-based cuticle development; embryonic heart tube development. 11 alleles are reported. The phenotypes of these alleles are annotated with: cardioblast; embryonic pericardial cell. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • >CG7073-PB translation from_gene[CG7073 sar1 FBgn0038947] seq_release:3 mol_weight=17488 cds_boundaries:(3R:18,175,129..18,176,636[+]) aa_length:155 transcript_info:[CG7073-RB seq_release:3] gene_info:[gene symbol:sar1 FBgn0038947 gene_boundaries:(3R:1 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q95SY7) LD39266p (CG7073-PB) [DrosMelano7227.FASTAC.txt]
  • CG7073-PB, isoform B [Drosophila melanogaster]gi|16648394|gb|AAL25462.1| LD39266p [Drosophila melanogaster]gi|21355813|ref|NP_651025.1| CG7073-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:join(18184165..18184213,18184285..18184350,18185247..18185482,18185559..18185675); ID=FBpp0083605; name=sar1-PB; parent=FBgn0038947,FBtr0084207; dbxref=FlyBase:FBpp0083605,FlyBase_Annotation_IDs:CG7073-PB,GB_protein:AAN14371.1,REFSEQ: [fly-100309-contam.fasta]
  • sar1 CG7073-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LD39266p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG7073-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:join(18184165..18184213,18184285..18184350,18185247..18185482,18185559..18185675); ID=FBpp0083605; name=sar1-PB; parent=FBgn0038947,FBtr0084207; dbxref=FlyBase:FBpp0083605,FlyBase_Annotation_IDs:CG7073-PB,GB_protein:AAN14371.1,REFSEQ:NP_651025,GB_protein:AAN14371; MD5=2d6285516cb1bf1f9ad61c22e601bb1f; length=155; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(18184165..18184213,18184285..18184350,18185247..18185482,18185559..18185675); ID=FBpp0083605; name=sar1-PB; parent=FBgn0038947,FBtr0084207; dbxref=FlyBase:FBpp0083605,FlyBase_Annotation_IDs:CG7073-PB,GB_protein:AAN14371.1,REFSEQ:NP_651025,GB_protein:AAN14371; MD5=2d6285516cb1bf1f9ad61c22e601bb1f; length=155; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • LD39266p OS=Drosophila melanogaster GN=sar1 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:join(18184165..18184213,18184285..18184350,18185247..18185482,18185559..18185675); ID=FBpp0083605; name=sar1-PB; parent=FBgn0038947,FBtr0084207; dbxref=FlyBase:FBpp0083605,FlyBase_Annotation_IDs:CG7073-PB,GB_protein:AAN14371.1,REFSEQ:NP_651025,GB_protein:AAN14371,FlyMine:FBpp0083605,modMine:FBpp0083605; MD5=2d6285516cb1bf1f9ad61c22e601bb1f; length=155; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
    • Organism: Drosophila melanogaster
    Length: 155 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    ER to Golgi transport vesicle [ISS]
    Biological Process: negative regulation of dendrite morphogenesis [IMP]
    chitin-based larval cuticle pattern formation [IMP]
    larval chitin-based cuticle development [IMP]
    embryonic heart tube development [IMP]
    intracellular protein transport [IEA]
    Molecular Function: GTP binding [IEA][ISS]
    GTPase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKDDKLAQH VPTLHPTSEE LSIGNMRFTT FDLGGHTQAR RVWKDYFPAV DAIVFLIDAW  60
   61 DRGRFQESKN ELDSLLTDEA LSNCPVLILG NKIDKPGAAS EDELRNVFGL YQLTTGKGKV 120
  121 ARADLPGRPL ELFMCSVLKR QGYGEGFRWL AQYID

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..155] PSI-BLAST 30.0 No description for 2gaoA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.21604035604783 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.23973347797292 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.17114488786105 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.1490380096706 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.14880143107309 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.194779852865789 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • nucleotide binding
    		•  0.0539023818858692 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.0533219218126988 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0377858914646858 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0377267149138016 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle