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Protein Overview: CG16941-PA

General Information:
Name(s) found: CG16941-PA / FBpp0082817 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG16941 (CG16941, FBgn0038464). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12825101..12828077. It has the cytological map location 89E6-89E7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: RNA binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization; regulation of alternative nuclear mRNA splicing, via spliceosome. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 784 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC]
    catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    spliceosomal complex [ISS]
    U2 snRNP [ISS]
    Biological Process: regulation of alternative nuclear mRNA splicing, via spliceosome [IMP]
    mitotic spindle organization [IMP]
    nuclear mRNA splicing, via spliceosome [IC][ISS]
    Molecular Function: RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATLDAEANE EQFGNDQPKS MSGPIIGIIY PPPEVRNIVD KTASFVARNG PEFEARIRQN  60
   61 ELGNPKFNFL NGGDPYHAYY RHKVNEFREG NDAGITALAS MKQLAVTSAA QQRQQELLKQ 120
  121 VVEQQFVPKE PPPEFEFIAD PPSISALDLD IVKLTAQFVA RNGRQFLTNL MSREQRNFQF 180
  181 DFLRPQHSLF QYFTKLLEQY TKVLIPPKDL LGKLRSESAP GRSSMNQVLE QVKYRANWQR 240
  241 HQEAQRRREE EKIERERVAY AQIDWHDFVV VETVDYQPFE SGNFPPPTNP DEVGARVLME 300
  301 ERLMDEEGDT EMQIESDDEG DSQANNLLDS GLKLSQMENR VGIQMKNVSS YGQPTGPKRD 360
  361 NTQVQDMDEA SSDEDTPTTK LQPSVAPMLP PTHDKVVVKK YDPKATQPKQ APMPTDEYLI 420
  421 SPITGEKIPA SKVSEHMRIG LLDPRWVEQR DKHTVEKINQ DNVFAAGTAI EASLKQLAER 480
  481 RTDIFGVGDE ETVIGKKLGE EETKKDDRVT WDGHTSSVEA ATRAARANIT LEEQIHQIHK 540
  541 VKGLLPDEEK EKIGPKPVGN KATLSAPPQP STKSQHSHSS QSQHHQGGGG GHHGHHNPHH 600
  601 HHPPHQQAPP HQSHHHHPPQ QPQPVMQLMQ LRPTMMQPPF GAGGGGYMNM QPGGIPQQIA 660
  661 PAPPVDIMEE EPPSKKIRSE DNLIPEADFI ATHKSPVTIQ VLVPNSDKSE WKLNGQMIAV 720
  721 TMALSEPIAN LKTKLQDETG MPPAKQKIFY EGMFFKDSNT MAFYNLVNGT TVHLQVKERG 780
  781 GRKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..122] PSI-BLAST 23.0 No description for 2dt6A was found.
    2 View Details [123..276] PSI-BLAST 26.154902 No description for 2dt7B was found.
    3 View Details [277..489] deduced N/A No confident structure predictions are available.
    4 View Details [490..678] PSI-BLAST 6.69897 Sec24
    5 View Details [679..784] PSI-BLAST 18.522879 Solution structure of Ubiquitin-like domain in SF3a120

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  2.786655943372 bayes_pls_golite062009
  • RNA binding
    		•  2.5865157751042 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.9984951714209 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.967509006593 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.96195140258726 bayes_pls_golite062009
  • protein binding
    		•  1.86841453215444 bayes_pls_golite062009
  • DNA binding
    		•  1.68336605464756 bayes_pls_golite062009
  • structural molecule activity
    		•  1.52853261170163 bayes_pls_golite062009
  • tubulin binding
    		•  1.52077315590062 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.27084865380092 bayes_pls_golite062009
  • microtubule binding
    		•  1.2489441153237 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle