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Protein Overview: decay-PA

General Information:
Name(s) found: decay-PA / FBpp0082755 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene death executioner caspase related to Apopain/Yama is referred to in FlyBase by the symbol Dmel\decay (CG14902, FBgn0028381). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12324780..12327394. It has the cytological map location 89B18. There is experimental evidence that it has the molecular function</span>: cysteine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: apoptosis. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 308 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA]
    Biological Process: apoptosis [IMP][NAS]
    proteolysis [IEA]
    programmed cell death [TAS]
    Molecular Function: cysteine-type endopeptidase activity [IDA][ISS][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDTDFSLFG QKNKHKKDKA DATKIAHTPT SELDLKRIII SRPTNEDTYE NCARAGIALI  60
   61 LNHKDVKGQK QRVGTERDRD DMEATLQGFG FDVRTFDDLT FSEINDTLKE VAREDHSQND 120
  121 CFVLAVMSHG TEGKVYAKDM SYPVERLWNP FLGDNCKTLK NKPKLFFIQA CRGANLEKAV 180
  181 EFSSFAVMTR ELVPEPAAAV QPITYAIPST ADILVFYSTF DKFFSFRNVD DGSWFIQSLC 240
  241 RVLDQAAANE AATPEGVELL RLLTAVNRKV AYEYQSNTKN EALNQMKEMP NFMSTLTKTF 300
  301 QLRVKPKT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..308] PSI-BLAST 81.30103 Apopain (caspase-3, cpp32)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle