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Protein Overview: Rpb7-PA

General Information:
Name(s) found: Rpb7-PA / FBpp0082591 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Rpb7 is referred to in FlyBase by the symbol Dmel\Rpb7 (CG31155, FBgn0051155). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11047971..11048849. It has the cytological map location 88E3. Based on sequence similarity, it is predicted to have molecular function</span>: DNA-directed RNA polymerase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription from RNA polymerase II promoter. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 173 amino acids

    Gene Ontology:
    Cellular Component: DNA-directed RNA polymerase II, core complex [ISS]
    Biological Process: transcription [IEA]
    transcription from RNA polymerase II promoter [ISS]
    Molecular Function: DNA-directed RNA polymerase activity [ISS]
    RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFYHISLEQE ILLHPRYFGP QLLETVKQKL YSEVEGTCTG KYGFVIAVTT IDQIGSGVIQ  60
   61 PGQGFVVYPV KYKAIVFRPF KGEVLDAVVK QINKVGMFAE IGPLSCFISH HSIPADMQFC 120
  121 PNGNPPCYKS KDEDVVISGE DKIRLKIVGT RVDATGIFAI GTLMDDYLGL VSN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..173] PSI-BLAST 35.0 Subunits Rpb4 and Rpb7 of human RNA polymerase II

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA polymerase activity
    		•  8.99678434167899 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  8.99678434167899 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  6.44182740737882 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  5.1118741250402 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.85462508375149 bayes_pls_golite062009
  • structural molecule activity
    		•  4.51553901145182 bayes_pls_golite062009
  • transferase activity
    		•  3.90847350895308 bayes_pls_golite062009
  • ribonuclease activity
    		•  3.83159232224897 bayes_pls_golite062009
  • DNA binding
    		•  3.53568546959418 bayes_pls_golite062009
  • RNA binding
    		•  3.49834780836233 bayes_pls_golite062009
    		• 2.80746531284205 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.41557476646435 bayes_pls_golite062009
  • exoribonuclease activity
    		•  2.41262897171619 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  2.38378389593693 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.10110937001387 bayes_pls_golite062009
  • binding
    		•  1.9712766790272 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.81524862921454 bayes_pls_golite062009
  • mRNA binding
    		•  1.660993824641 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.62996999055328 bayes_pls_golite062009
  • protein binding
    		•  1.55473080522232 bayes_pls_golite062009
  • translation regulator activity
    		•  1.46320772716954 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.40718318783582 bayes_pls_golite062009
  • translation initiation factor activity
    		•  1.27539679024898 bayes_pls_golite062009
  • transcription activator activity
    		•  1.09079153283893 bayes_pls_golite062009
  • catalytic activity
    		•  1.02941336036162 bayes_pls_golite062009
  • transcription factor activity
    		•  0.937752547283357 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.85691075793641 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.83268201349295 bayes_pls_golite062009
  • hydrolase activity
    		•  0.724860465280978 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.583085644017496 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  0.474251377131502 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  0.47336621289748 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  0.47336621289748 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.223941674251642 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

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    Created and Maintained by: Michael Riffle