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Protein Overview: Ect3-PA

General Information:
Name(s) found: Ect3-PA / FBpp0081961 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\Ect3 (CG3132, FBgn0260746). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7825029..7829239. It has the cytological map location 87A7. Based on sequence similarity, it is predicted to have molecular function</span>: beta-galactosidase activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 637 amino acids

    Gene Ontology:
    Cellular Component: lysosome [ISS]
    Biological Process: carbohydrate metabolic process [IEA]
    autophagic cell death [IEP]
    salivary gland cell autophagic cell death [IEP]
    Molecular Function: cation binding [IEA]
    beta-galactosidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFSVVVLVA LLPLLGAVSA NRTFVVDYEK DQFLKDGEPF RFIAGSFHYF RAHPATWQRH  60
   61 LRTMRAAGLN AVTTYVEWSL HNPRDGVYVW SGIADLEHFI RLAVGEDLLV ILRPGPYICA 120
  121 ERDMGGFPYW LLNKYPGIQL RTADVNYLSE IRIWYTQLFA KMNKYLYGNG GPIIMVQVEN 180
  181 EYGSFYACDL NYRNWLRDET ESHVKGQAVL FTNDGPSVLR CGKIQGVLAT MDFGATNDLK 240
  241 PIWAKFRRYQ PKGPLVNAEY YPGWLTHWTE PMANVSTQSI TSTFINMLDH GASVNFYMFY 300
  301 GGTNFGFTAG ANDIGPGNYM ADITSYDYDA PMTEAGDPTP KYQALRRIIG RYLPLPNQPV 360
  361 PGPVPKRSYG TVRLTTCCSL LSSEARSRLS TGFVQSAKPK SFEALGQYSG LVLYETWLPS 420
  421 FQRDPSILSV PGLADRGYVY VDGEFVGILA RETPVFELPL SASAGRRFQI IVENQGRINY 480
  481 GRQLNDFKGI LRDVRLDKQV LSNWNMTQFP LESYDNLEQL ITQSDEAVRQ GFQELKKLRT 540
  541 MLRTGPAIYH GQLDIQKESD LADTYLDMSG WGKGIVFVNG ENLGRYWPLV GPQVTLYVPA 600
  601 AVLKAGSNRL VVVEYQQTPA SQELHFRDTP ILNARTV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..472] PSI-BLAST 43.09691 Native structure of beta-galactosidase from Penicillium sp.
    2 View Details [473..637] FFAS03 1.76 beta-Glucuronidase; beta-Glucuronidase, domain 3

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  6.26329339735894 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  5.92180849080637 bayes_pls_golite062009
  • hydrolase activity
    		•  3.98075336331567 bayes_pls_golite062009
  • hexosaminidase activity
    		•  3.21852337137039 bayes_pls_golite062009
  • beta-N-acetylhexosaminidase activity
    		•  2.69072465526737 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • glucosidase activity
    		•  1.85545420386612 bayes_pls_golite062009
  • galactosidase activity
    		•  1.26155841119987 bayes_pls_golite062009
  • sugar binding
    		•  1.05517664149942 bayes_pls_golite062009
  • alpha-glucosidase activity
    		•  1.00973231642658 bayes_pls_golite062009
  • beta-glucuronidase activity
    		•  0.55376725638834 bayes_pls_golite062009
  • mannosidase activity
    		•  0.48536369022293 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.36193860645628 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • binding
    		•  0.129334455670168 bayes_pls_golite062009
  • beta-galactosidase activity
    		•  0.0137149865738109 bayes_pls_golite062009
    2
    Term Confidence Notes
  • sugar binding
    		•  1.88707446766738 bayes_pls_golite062009
  • monosaccharide binding
    		•  1.5016957206605 bayes_pls_golite062009
  • hydrolase activity
    		•  1.33447645932315 bayes_pls_golite062009
  • binding
    		•  1.18625504714684 bayes_pls_golite062009
  • carbohydrate binding
    		•  1.13274900486168 bayes_pls_golite062009
  • peptidase activity
    		•  0.619147192549203 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.338739134947705 bayes_pls_golite062009
  • fucose binding
    		•  0.25045987594275 bayes_pls_golite062009
  • protein binding
    		•  0.0768945417872265 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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