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Protein Overview: CG6465-PA

General Information:
Name(s) found: CG6465-PA / FBpp0081799 [FlyBase]
Description(s) found:
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  • gi|21356353|ref|NP_650004.1| CG6465 [Drosophila melanogaster] [NCBI NR]
  • gi|15010432|gb|AAK77264.1| GH04054p [Drosophila melanogaster] [NCBI NR]
  • gi|10726439|gb|AAG22139.1| CG6465 [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG6465 (CG6465, FBgn0037818). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6501281..6502892. It has the cytological map location 86C4. Based on sequence similarity, it is predicted to have molecular function</span>: aminoacylase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis; cellular amino acid metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG6465-PA translation from_gene[CG6465 CG6465 FBgn0037818] seq_release:3 mol_weight=45131 cds_boundaries:(3R:6,501,383..6,502,900[-]) aa_length:401 transcript_info:[CG6465-RA seq_release:3] gene_info:[gene symbol:CG6465 FBgn0037818 gene_boundaries:(3R [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9I7K3) CG6465 protein (GH04054p) [DrosMelano7227.FASTAC.txt]
  • (AE003688) CG6465 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG6465-PA [Drosophila melanogaster]gi|15010432|gb|AAK77264.1| GH04054p [Drosophila melanogaster]gi|21356353|ref|NP_650004.1| CG6465-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(6501362..6501566,6501625..6501758,6501816..6502099,6502164..6502310,6502372..6502716,6502792..6502882); ID=FBpp0081799; name=CG6465-PA; parent=FBgn0037818,FBtr0082323; dbxref=FlyBase:FBpp0081799,FlyBase_Annotation_IDs:CG646 [fly-100309-contam.fasta]
  • CG6465-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GH04054p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(6501362..6501566,6501625..6501758,6501816..6502099,6502164..6502310,6502372..6502716,6502792..6502882); ID=FBpp0081799; name=CG6465-PA; parent=FBgn0037818,FBtr0082323; dbxref=FlyBase:FBpp0081799,FlyBase_Annotation_IDs:CG6465-PA,GB_protein:AAG22139.1,REFSEQ:NP_650004,GB_protein:AAG22139; MD5=e76fb1b312de280864499481d258a697; length=401; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(6501362..6501566,6501625..6501758,6501816..6502099,6502164..6502310,6502372..6502716,6502792..6502882); ID=FBpp0081799; name=CG6465-PA; parent=FBgn0037818,FBtr0082323; dbxref=FlyBase:FBpp0081799,FlyBase_Annotation_IDs:CG6465-PA,GB_protein:AAG22139.1,REFSEQ:NP_650004,GB_protein:AAG22139; MD5=e76fb1b312de280864499481d258a697; length=401; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG6465 OS=Drosophila melanogaster GN=CG6465 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(6501362..6501566,6501625..6501758,6501816..6502099,6502164..6502310,6502372..6502716,6502792..6502882); ID=FBpp0081799; name=CG6465-PA; parent=FBgn0037818,FBtr0082323; dbxref=FlyBase:FBpp0081799,FlyBase_Annotation_IDs:CG6465-PA,GB_protein:AAG22139.1,REFSEQ:NP_650004,GB_protein:AAG22139,FlyMine:FBpp0081799,modMine:FBpp0081799; MD5=e76fb1b312de280864499481d258a697; length=401; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(10677070..10677160,10676650..10676994,10676442..10676588,10676094..10676377,10675903..10676036,10675640..10675844)); ID=FBpp0081799; name=CG6465-PA; parent=FBgn0037818,FBtr0082323; dbxref=FlyBase:FBpp0081799,FlyBase_Annotation_IDs:CG6465-PA,GB_protein:AAG22139.1,REFSEQ:NP_650004,GB_protein:AAG22139,FlyMine:FBpp0081799,modMine:FBpp0081799; MD5=e76fb1b312de280864499481d258a697; length=401; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(10677070..10677160,10676650..10676994,10676442..10676588,10676094..10676377,10675903..10676036,10675640..10675844)); ID=FBpp0081799; name=CG6465-PA; parent=FBgn0037818,FBtr0082323; dbxref=FlyBase:FBpp0081799,FlyBase_Annotation_IDs:CG6465-PA,GB_protein:AAG22139.1,REFSEQ:NP_650004,GB_protein:AAG22139,FlyMine:FBpp0081799,modMine:FBpp0081799; MD5=e76fb1b312de280864499481d258a697; length=401; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Aminoacylase-1 OS=Drosophila melanogaster GN=CG6465 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0081799 type=protein; loc=3R:complement(join(10677070..10677160,10676650..10676994,10676442..10676588,10676094..10676377,10675903..10676036,10675640..10675844)); ID=FBpp0081799; name=CG6465-PA; parent=FBgn0037818,FBtr0082323; dbxref=FlyBase:FBpp0081799,FlyBase_Annotation_IDs:CG6465-PA,GB_protein:AAG22139.1,REFSEQ:NP_650004,GB_protein:AAG22139,FlyMine:FBpp0081799,modMine:FBpp0081799; MD5=e76fb1b312de280864499481d258a697; length=401; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(10677070..10677160,10676650..10676994,10676442..10676588,10676094..10676377,10675903..10676036,10675640..10675844)); ID=FBpp0081799; name=CG6465-PA; parent=FBgn0037818,FBtr0082323; dbxref=FlyBase:FBpp0081799,FlyBase_Annotation_IDs:CG6465-PA,GB_protein:AAG22139.1,REFSEQ:NP_650004,GB_protein:AAG22139,UniProt/TrEMBL:Q9I7K3,FlyMine:FBpp0081799,modMine:FBpp0081799; MD5=e76fb1b312de280864499481d258a697; length=401; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 401 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: proteolysis [IEA]
    cellular amino acid metabolic process [IEA]
    Molecular Function: protein binding [IEA]
    aminoacylase activity [ISS]
    metallopeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATSKWESDE EIQYFREYLR IPSVHPDPDY APCVEFLRRQ ANLMDLPMKV YYPANEQNPV  60
   61 VVLTWKGLNP ELPSILLNSH MDVVPVFPEN WTHPPFGADI DEEGRIFARG TQDMKSVGMQ 120
  121 HLAAVRALKR SGAKFKRTIH ISFVADEEMG GRYGMRPFVP TEDFRALNVG FAMDEGLASP 180
  181 DEQLPLFYAE RAVWRVYFNI SGTAGHGSLL LPNTAGEKLN YIVGKMMEFR RSQVQRLQNN 240
  241 PELVIGDVTT INLTKLGGGV QSNVVPPLLM VCFDCRLALD VDFEEFEANL HKWCADVGGG 300
  301 IEITYEQKQP KVPPTAIDGS NPFWLAFKKA TDEMHISIKP QIFTGGTDSR YIRAVGIPAL 360
  361 GFSPMNNTPV LLHDHDEFIQ ADIYLRGVQI FQKIISNIAN V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..184] PSI-BLAST 35.522879 Zn-binding domain of the T347G mutant of human aminoacylase-I
    2 View Details [185..312] FFAS03 3.91 Crystal Structure of Bacillus Subtilis YXEP Protein (APC1829), a Dinuclear Metal Binding Peptidase from M20 Family
    3 View Details [313..401] PSI-BLAST 10.69897 Zn-binding domain of the T347G mutant of human aminoacylase-I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  3.81939870413022 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  3.44941516786903 bayes_pls_golite062009
  • hydrolase activity
    		•  2.78642767439288 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.62986226691096 bayes_pls_golite062009
  • catalytic activity
    		•  1.3989281287879 bayes_pls_golite062009
  • metallopeptidase activity
    		•  1.19468588994762 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  0.891655769761122 bayes_pls_golite062009
  • metalloexopeptidase activity
    		•  0.53612355623424 bayes_pls_golite062009
  • metallocarboxypeptidase activity
    		•  0.180859448845431 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.0966237570696103 bayes_pls_golite062009
    2
    Term Confidence Notes
  • peptidase activity
    		•  3.2460337099697 bayes_pls_golite062009
  • hydrolase activity
    		•  2.89801951009786 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.58805472741431 bayes_pls_golite062009
  • catalytic activity
    		•  1.84228605319441 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.574424638244179 bayes_pls_golite062009
  • binding
    		•  0.477837256878116 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle