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Protein Overview: jumu-PA

General Information:
Name(s) found: jumu-PA / FBpp0081715 [FlyBase]
Description(s) found:
Found 30 descriptions.
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  • The gene jumeau is referred to in FlyBase by the symbol Dmel\jumu (CG4029, FBgn0015396). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6175906..6187343. It has the cytological map location 86B1. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: neuroblast fate determination; compound eye development; dendrite morphogenesis; neuron development; asymmetric protein localization; muscle organ development; imaginal disc-derived wing morphogenesis. 36 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; rhabdomere; eye; wing margin bristle; macrochaeta; RP2sib neuron; wing; ommatidium; wing hair. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 719 amino acids

    Gene Ontology:
    Cellular Component: polytene chromosome chromocenter [IDA]
    nucleus [IDA][NAS]
    polytene chromosome [IDA]
    nucleolus [IDA]
    chromatin [IDA]
    Biological Process: dorsal closure [TAS]
    muscle organ development [IMP]
    transcription [ISS]
    imaginal disc-derived wing morphogenesis [IMP]
    neuroblast fate determination [IMP]
    regulation of transcription, DNA-dependent [IEA]
    neuron development [IMP]
    chromatin organization [TAS]
    compound eye development [IMP]
    asymmetric protein localization [IMP]
    dendrite morphogenesis [IMP]
    Molecular Function: transcription factor activity [ISS][NAS]
    sequence-specific DNA binding [IEA]
    chromatin binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFELEDYSSG IHEGFFSKYA DAAGPSLDFY VSDSMQEMLN VDIRAEIANV VGSSSSDLTS  60
   61 SLDQTLEAIS AINNNQSNGN SSQSASYNAN ANFLTSSGLH ASPTAKWMGS SANFWSNSDY 120
  121 YADLGACVNP ISVMPLINST SAGMFSPKKN KTASSTQGRS GAVPSSPSAE RDQHKSHLTF 180
  181 SPAQMKVSAG SMRRDQVMAH IPKQISVVTG TGTTAPATMA TNSVLQRRNS SAVDAVRKDL 240
  241 VTELRKAQSS PVPNSLEELG KGKGSTLLNA SVGATNTIKL APGIGGLTFA NSAAYQKLKQ 300
  301 TSLVKSPGGI SPGAGSNMGL KREDSNKRGL QASTTPKSIA SAANSPHHQM QSNYSLGSPS 360
  361 SLSSSSASSP LGNVSNLVNI ANNNTSGAGS GLVKPLQQKV KLPPVGSPFP KPAYSYSCLI 420
  421 ALALKNSRAG SLPVSEIYSF LCQHFPYFEN APSGWKNSVR HNLSLNKCFE KIERPATNGN 480
  481 QRKGCRWAMN PDRINKMDEE VQKWSRKDPA AIRGAMVYPQ HLESLERGEM KHGSADSDVE 540
  541 LDSQSEIEES SDLEEHEFED TMVDAMLVEE EDEEEDGDDD EQIINDFDAE DERHANGNQA 600
  601 NNLPINHPLL GQKSNDFDIE VGDLYDAIDI EDDKESVRRI ISNDQHIIEL NPADLNATDG 660
  661 YNQQPALKRA RVDINYAIGP AGELEQQYGQ KVKVQQVIQP QQHPPTYNRR KMPLVNRVI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..132] PSI-BLAST 24.0 RBP1
    2 View Details [133..276] MSA 2.194995 View MSA. No confident structure predictions are available.
    3 View Details [277..410] deduced N/A No confident structure predictions are available.
    4 View Details [411..509] PSI-BLAST 29.0 Adipocyte-transcription factor FREAC-11 (s12, fkh-14)
    5 View Details [510..719] MSA 1.214995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  5.55329976718261 bayes_pls_golite062009
  • DNA binding
    		•  5.08959163553491 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.99681957904233 bayes_pls_golite062009
  • transcription factor activity
    		•  4.33152142980289 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.85678231380989 bayes_pls_golite062009
  • transcription activator activity
    		•  3.70589483230587 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.58179858678904 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.60738445921725 bayes_pls_golite062009
  • protein binding
    		•  1.80415286835431 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.2723726467408 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.96257232341735 bayes_pls_golite062009
  • transcription factor binding
    		•  0.85714789329232 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.66743181561551 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.322180400748724 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.23177057841536 bayes_pls_golite062009
  • structural molecule activity
    		•  0.111941063082739 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle