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View Structure Prediction Details

Protein: jumu-PA
Organism: Drosophila melanogaster
Length: 719 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for jumu-PA.

Description E-value Query
Range
Subject
Range
gi|54637932, gi|... - gi|54637932|gb|EAL27334.1| GA17887 [Drosophila pseudoobscura pseudoobscura], gi|125773877|ref|XP_001...
gi|54637932|gb|E... - GA17887-PA [Drosophila pseudoobscura], GA17887 [Drosophila pseudoobscura pseudoobscura]
247.0 [0..1] [719..1]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFELEDYSSG IHEGFFSKYA DAAGPSLDFY VSDSMQEMLN VDIRAEIANV VGSSSSDLTS  60
   61 SLDQTLEAIS AINNNQSNGN SSQSASYNAN ANFLTSSGLH ASPTAKWMGS SANFWSNSDY 120
  121 YADLGACVNP IS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.0
Match: 1i3qA
Description: RBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [133-276]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VMPLINSTSA GMFSPKKNKT ASSTQGRSGA VPSSPSAERD QHKSHLTFSP AQMKVSAGSM  60
   61 RRDQVMAHIP KQISVVTGTG TTAPATMATN SVLQRRNSSA VDAVRKDLVT ELRKAQSSPV 120
  121 PNSLEELGKG KGSTLLNASV GATN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [277-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIKLAPGIGG LTFANSAAYQ KLKQTSLVKS PGGISPGAGS NMGLKREDSN KRGLQASTTP  60
   61 KSIASAANSP HHQMQSNYSL GSPSSLSSSS ASSPLGNVSN LVNIANNNTS GAGSGLVKPL 120
  121 QQKVKLPPVG SPFP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [411-509]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPAYSYSCLI ALALKNSRAG SLPVSEIYSF LCQHFPYFEN APSGWKNSVR HNLSLNKCFE  60
   61 KIERPATNGN QRKGCRWAMN PDRINKMDEE VQKWSRKDP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.0
Match: 1d5vA
Description: Adipocyte-transcription factor FREAC-11 (s12, fkh-14)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 5.08959163553491 bayes_pls_golite062009
nucleic acid binding 4.99681957904233 bayes_pls_golite062009
transcription factor activity 4.33152142980289 bayes_pls_golite062009
transcription repressor activity 3.85678231380989 bayes_pls_golite062009
transcription activator activity 3.70589483230587 bayes_pls_golite062009
sequence-specific DNA binding 3.58179858678904 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.60738445921725 bayes_pls_golite062009
protein binding 1.80415286835431 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.2723726467408 bayes_pls_golite062009
specific transcriptional repressor activity 0.96257232341735 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.66743181561551 bayes_pls_golite062009
transcription corepressor activity 0.322180400748724 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.23177057841536 bayes_pls_golite062009
structural molecule activity 0.111941063082739 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [510-719]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAIRGAMVYP QHLESLERGE MKHGSADSDV ELDSQSEIEE SSDLEEHEFE DTMVDAMLVE  60
   61 EEDEEEDGDD DEQIINDFDA EDERHANGNQ ANNLPINHPL LGQKSNDFDI EVGDLYDAID 120
  121 IEDDKESVRR IISNDQHIIE LNPADLNATD GYNQQPALKR ARVDINYAIG PAGELEQQYG 180
  181 QKVKVQQVIQ PQQHPPTYNR RKMPLVNRVI 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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