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View Structure Prediction Details

Protein: jumu-PA
Organism: Drosophila melanogaster
Length: 719 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for jumu-PA.

Description E-value Query
Range
Subject
Range
gi|54637932, gi|... - gi|54637932|gb|EAL27334.1| GA17887 [Drosophila pseudoobscura pseudoobscura], gi|125773877|ref|XP_001...
gi|54637932|gb|E... - GA17887-PA [Drosophila pseudoobscura], GA17887 [Drosophila pseudoobscura pseudoobscura]
247.0 [0..1] [719..1]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFELEDYSSG IHEGFFSKYA DAAGPSLDFY VSDSMQEMLN VDIRAEIANV VGSSSSDLTS  60
   61 SLDQTLEAIS AINNNQSNGN SSQSASYNAN ANFLTSSGLH ASPTAKWMGS SANFWSNSDY 120
  121 YADLGACVNP IS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.0
Match: 1i3qA
Description: RBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [133-276]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VMPLINSTSA GMFSPKKNKT ASSTQGRSGA VPSSPSAERD QHKSHLTFSP AQMKVSAGSM  60
   61 RRDQVMAHIP KQISVVTGTG TTAPATMATN SVLQRRNSSA VDAVRKDLVT ELRKAQSSPV 120
  121 PNSLEELGKG KGSTLLNASV GATN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [277-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIKLAPGIGG LTFANSAAYQ KLKQTSLVKS PGGISPGAGS NMGLKREDSN KRGLQASTTP  60
   61 KSIASAANSP HHQMQSNYSL GSPSSLSSSS ASSPLGNVSN LVNIANNNTS GAGSGLVKPL 120
  121 QQKVKLPPVG SPFP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [411-509]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPAYSYSCLI ALALKNSRAG SLPVSEIYSF LCQHFPYFEN APSGWKNSVR HNLSLNKCFE  60
   61 KIERPATNGN QRKGCRWAMN PDRINKMDEE VQKWSRKDP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.0
Match: 1d5vA
Description: Adipocyte-transcription factor FREAC-11 (s12, fkh-14)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 5.08959163553491 bayes_pls_golite062009
nucleic acid binding 4.99681957904233 bayes_pls_golite062009
transcription factor activity 4.33152142980289 bayes_pls_golite062009
transcription repressor activity 3.85678231380989 bayes_pls_golite062009
transcription activator activity 3.70589483230587 bayes_pls_golite062009
sequence-specific DNA binding 3.58179858678904 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.60738445921725 bayes_pls_golite062009
protein binding 1.80415286835431 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.2723726467408 bayes_pls_golite062009
specific transcriptional repressor activity 0.96257232341735 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.66743181561551 bayes_pls_golite062009
transcription corepressor activity 0.322180400748724 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.23177057841536 bayes_pls_golite062009
structural molecule activity 0.111941063082739 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [510-719]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAIRGAMVYP QHLESLERGE MKHGSADSDV ELDSQSEIEE SSDLEEHEFE DTMVDAMLVE  60
   61 EEDEEEDGDD DEQIINDFDA EDERHANGNQ ANNLPINHPL LGQKSNDFDI EVGDLYDAID 120
  121 IEDDKESVRR IISNDQHIIE LNPADLNATD GYNQQPALKR ARVDINYAIG PAGELEQQYG 180
  181 QKVKVQQVIQ PQQHPPTYNR RKMPLVNRVI 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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