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Protein Overview: FBpp0304185, Rho...

General Information:
Name(s) found: FBpp0304185 [FlyBase]
RhoGDI-PA / FBpp0074665 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=3L:join(19923931..19924114,19924188..19924297,19924363..19924477,19925082..19925278); ID=FBpp0304185; name=RhoGDI-PB; parent=FBgn0036921,FBtr0331800; dbxref=FlyBase:FBpp0304185,FlyBase_Annotation_IDs:CG7823-PB,REFSEQ:NP_001262080,GB_protein:AGB94773; MD5=7d49142a2ac101bfc756b97b4d666346; length=201; release=r5.56; species=Dmel; [FlyBase]
  • The gene RhoGDI is referred to in FlyBase by the symbol Dmel\RhoGDI (CG7823, FBgn0036921). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19921907..19926032. It has the cytological map location 76D5. Based on sequence similarity, it is predicted to have molecular function</span>: Rho GDP-dissociation inhibitor activity. The biological processes in which it is involved are not known. 15 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 201 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: NONE FOUND
    Molecular Function: Rho GDP-dissociation inhibitor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAETETKHHP EHHDDDVHDA NYQAPPEKTI EEIMAADQED ESLRRYKEAL LGAAQTEKII  60
   61 VEPNDPRKVI VKKLALVVEG RDDMELDLTG DLSQLKKQLF VIKEGVQYKV RIDFIVQREI 120
  121 VHGLKYVQKT SRLGVNVDKM KHMVGSYPPK KEIQFYLTPA EEAPSGTFSR GTYSVSSVFT 180
  181 DDDKHIHLEW DWTFEIKKDW A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..201] PSI-BLAST 84.0 Rho GDP-dissociation inhibitor 1, RhoGDI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  4.21900602727099 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.82728537491772 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  2.79599274364249 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  2.7120102542099 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  2.70863932585459 bayes_pls_golite062009
  • potassium channel activity
    		•  2.69685666968196 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  2.69627305312298 bayes_pls_golite062009
  • binding
    		•  2.65544526722793 bayes_pls_golite062009
  • cation channel activity
    		•  2.65302958856525 bayes_pls_golite062009
  • gated channel activity
    		•  2.52278796517374 bayes_pls_golite062009
  • transporter activity
    		•  2.46466249895824 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.37642404692102 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.37262306131842 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  2.32502571419352 bayes_pls_golite062009
  • channel activity
    		•  2.3181005726144 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  2.3181005726144 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.31677709260544 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.28077016868353 bayes_pls_golite062009
  • ion channel activity
    		•  2.2553711462771 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.23522391314947 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.15379228421204 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  1.86598930407084 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  1.81486809950722 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  1.81486809950722 bayes_pls_golite062009
  • Rho GDP-dissociation inhibitor activity
    		•  1.67374100547551 bayes_pls_golite062009
  • actin filament binding
    		•  1.67203076960313 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.55727555528218 bayes_pls_golite062009
  • protein binding
    		•  1.50286160643298 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.44225801859996 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.42486878565247 bayes_pls_golite062009
  • clathrin binding
    		•  1.23902179002817 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.12993648323166 bayes_pls_golite062009
  • signal transducer activity
    		•  1.12993648323166 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.05880190577068 bayes_pls_golite062009
  • GDP-dissociation inhibitor activity
    		•  0.580608094701522 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle