Protein Overview: Eip74EF-PD, Eip7...

General Information:
Name(s) found:	Eip74EF-PD / FBpp0099825 [FlyBase] Eip74EF-PB / FBpp0074967 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7293965\|gb\|AAF49324.1\| Ecdysone-induced protein 74EF, isoform B [Drosophila melanogaster] [NCBI NR] gi\|62472249\|ref\|NP_001014590.1\| Ecdysone-induced protein 74EF, isoform D [Drosophila melanogaster] [NCBI NR] gi\|61678454\|gb\|AAX52740.1\| Ecdysone-induced protein 74EF, isoform D [Drosophila melanogaster] [NCBI NR] gi\|45644947\|sp\|P11536.2\|E74EB_DROME RecName: Full=Ecdysone-induced protein 74EF isoform B; AltName: Full=ETS-related protein E74B [NCBI NR] gi\|24666017\|ref\|NP_730288.1\| Ecdysone-induced protein 74EF, isoform B [Drosophila melanogaster] [NCBI NR] gi\|157310\|gb\|AAA28494.1\| E74B protein [NCBI NR] Ecdysone-induced protein 74EF isoform B OS=Drosophila melanogaster GN=Eip74EF PE=2 SV=2 [Swiss-Prot] (P11536) Ecdysone-induced protein 74EF isoform B (ETS-related protein E74B) [Swiss-Prot] The gene Ecdysone-induced protein 74EF is referred to in FlyBase by the symbol Dmel\Eip74EF (CG32180, FBgn0000567). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17553258..17612407. It has the cytological map location 74D4-74E2. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: cellular process; autophagy; salivary gland cell autophagic cell death. 42 alleles are reported. The phenotypes of these alleles are annotated with: larva; salivary gland; adult epidermis; cuticle; air bubble; procephalic segment; anterior pupal spiracle. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] >CG32180-PB translation from_gene[CG32180 Eip74EF FBgn0000567] seq_release:3 mol_weight=94812 cds_boundaries:(3L:17,510,652..17,524,710[-]) aa_length:883 transcript_info:[CG32180-RB seq_release:3] gene_info:[gene symbol:Eip74EF synonyms:[CG6285 CG6273] [hmr_yeast5_DM3-1_pombe.fasta] (AE003523) Eip74EF gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG32180-PB, isoform B [Drosophila melanogaster]gi\|24666017\|ref\|NP_730288.1\| CG32180-PB [Drosophila melanogaster]gi\|45644947\|sp\|P11536\|E74B_DROME Ecdysone-induced protein 74EF isoform B (ETS-related protein E74B)gi\|157310\|gb\|AAA28494.1\| E74B protein [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17567893..17568931); ID=FBpp0074967; name=Eip74EF-PB; parent=FBgn0000567,FBtr0075204; dbxref=FlyBase_Annotation_IDs:CG32180-PB,FlyBase:FBpp0074967,GB_protein:AAF49324 [fly-100309-contam.fasta] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17567893..17568931); ID=FBpp0099825; name=Eip74EF-PD; parent=FBgn0000567,FBtr0100411; dbxref=FlyBase_Annotation_IDs:CG32180-PD,FlyBase:FBpp0099825,GB_protein:AAX52740 [fly-100309-contam.fasta] E74B protein [nr-271106-contam.fasta] Ecdysone-induced protein 74EF isoform B (ETS-related protein E74B) [nr-271106-contam.fasta] Ecdysone-induced protein 74EF CG32180-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] CG32180-PD, isoform D [Drosophila melanogaster] [nr-271106-contam.fasta] Ecdysone-induced protein 74EF CG32180-PD, isoform D [Drosophila melanogaster] [nr-271106-contam.fasta] CG32180-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17567893..17568931); ID=FBpp0074967; name=Eip74EF-PB; parent=FBgn0000567,FBtr0075204; dbxref=FlyBase_Annotation_IDs:CG32180-PB,FlyBase:FBpp0074967,GB_protein:AAF49324.1,REFSEQ:NP_730288,GB_protein:AAF49324; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17567893..17568931); ID=FBpp0099825; name=Eip74EF-PD; parent=FBgn0000567,FBtr0100411; dbxref=FlyBase_Annotation_IDs:CG32180-PD,FlyBase:FBpp0099825,GB_protein:AAX52740.1,REFSEQ:NP_001014590,GB_protein:AAX52740; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17567893..17568931); ID=FBpp0074967; name=Eip74EF-PB; parent=FBgn0000567,FBtr0075204; dbxref=FlyBase_Annotation_IDs:CG32180-PB,FlyBase:FBpp0074967,GB_protein:AAF49324.1,REFSEQ:NP_730288,GB_protein:AAF49324; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17567893..17568931); ID=FBpp0099825; name=Eip74EF-PD; parent=FBgn0000567,FBtr0100411; dbxref=FlyBase_Annotation_IDs:CG32180-PD,FlyBase:FBpp0099825,GB_protein:AAX52740.1,REFSEQ:NP_001014590,GB_protein:AAX52740; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17567893..17568931); ID=FBpp0074967; name=Eip74EF-PB; parent=FBgn0000567,FBtr0075204; dbxref=FlyBase_Annotation_IDs:CG32180-PB,FlyBase:FBpp0074967,GB_protein:AAF49324.1,REFSEQ:NP_730288,GB_protein:AAF49324; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:complement(17554870..17555858,17557706..17557960,17558457..17558825,17567893..17568931); ID=FBpp0099825; name=Eip74EF-PD; parent=FBgn0000567,FBtr0100411; dbxref=FlyBase_Annotation_IDs:CG32180-PD,FlyBase:FBpp0099825,GB_protein:AAX52740.1,REFSEQ:NP_001014590,GB_protein:AAX52740,FlyMine:FBpp0099825,modMine:FBpp0099825; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:complement(join(17574793..17575831,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0074967; name=Eip74EF-PB; parent=FBgn0000567,FBtr0075204; dbxref=FlyBase_Annotation_IDs:CG32180-PB,FlyBase:FBpp0074967,GB_protein:AAF49324.1,REFSEQ:NP_730288,GB_protein:AAF49324; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(17574793..17575831,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0099825; name=Eip74EF-PD; parent=FBgn0000567,FBtr0100411; dbxref=FlyBase_Annotation_IDs:CG32180-PD,FlyBase:FBpp0099825,GB_protein:AAX52740.1,REFSEQ:NP_001014590,GB_protein:AAX52740,FlyMine:FBpp0099825,modMine:FBpp0099825; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(17574793..17575831,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0074967; name=Eip74EF-PB; parent=FBgn0000567,FBtr0075204; dbxref=FlyBase_Annotation_IDs:CG32180-PB,FlyBase:FBpp0074967,GB_protein:AAF49324.1,REFSEQ:NP_730288,GB_protein:AAF49324; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3L:complement(join(17574793..17575831,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0099825; name=Eip74EF-PD; parent=FBgn0000567,FBtr0100411; dbxref=FlyBase_Annotation_IDs:CG32180-PD,FlyBase:FBpp0099825,GB_protein:AAX52740.1,REFSEQ:NP_001014590,GB_protein:AAX52740,FlyMine:FBpp0099825,modMine:FBpp0099825; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0074967 type=protein; loc=3L:complement(join(17574793..17575831,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0074967; name=Eip74EF-PB; parent=FBgn0000567,FBtr0075204; dbxref=FlyBase_Annotation_IDs:CG32180-PB,FlyBase:FBpp0074967,GB_protein:AAF49324.1,REFSEQ:NP_730288,GB_protein:AAF49324; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0099825 type=protein; loc=3L:complement(join(17574793..17575831,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0099825; name=Eip74EF-PD; parent=FBgn0000567,FBtr0100411; dbxref=FlyBase_Annotation_IDs:CG32180-PD,FlyBase:FBpp0099825,GB_protein:AAX52740.1,REFSEQ:NP_001014590,GB_protein:AAX52740,FlyMine:FBpp0099825,modMine:FBpp0099825; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:complement(join(17574793..17575831,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0074967; name=Eip74EF-PB; parent=FBgn0000567,FBtr0075204; dbxref=FlyBase_Annotation_IDs:CG32180-PB,FlyBase:FBpp0074967,GB_protein:AAF49324.1,REFSEQ:NP_730288,GB_protein:AAF49324,UniProt/Swiss-Prot:P11536; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3L:complement(join(17574793..17575831,17565357..17565725,17564606..17564860,17561770..17562758)); ID=FBpp0099825; name=Eip74EF-PD; parent=FBgn0000567,FBtr0100411; dbxref=FlyBase_Annotation_IDs:CG32180-PD,FlyBase:FBpp0099825,GB_protein:AAX52740.1,REFSEQ:NP_001014590,GB_protein:AAX52740,UniProt/Swiss-Prot:P11536,FlyMine:FBpp0099825,modMine:FBpp0099825; MD5=88870aba986145d8d2046721ab3fc48b; length=883; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	883 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS][NAS]
Biological Process:	cell death [TAS] regulation of development, heterochronic [TAS] oogenesis [NAS] autophagy [IMP] regulation of transcription, DNA-dependent [IEA][ISS] salivary gland cell autophagic cell death [IMP][NAS] regulation of transcription [NAS] cellular process [IMP]
Molecular Function:	transcription factor activity [IEA][TAS] specific RNA polymerase II transcription factor activity [ISS] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIMVQHLVAA SAHNFASQAA ASLVNVSSSS SSSSSSSSSS LSLSSSSSSS SLSSATPTPV  60
   61 ASPVTPTSPP PAAAAPAEAS PPAGAELQED GQQAKTQEDP TMKDQDMLEK TRQEVKDPVN 120
  121 VEEPGAIVDT ESVMARQSPS PVASTKVPES LEEISNKSPP VQEDEEESES VASDCREFKV 180
  181 LYNHLRQQQH HHSPSSPDKT RSTLDDVSKI LWERKQQLQR SSVITAAPTL QPQQHQQPMS 240
  241 DIEDEETLED VDDADADVEA DAEDEELLEQ YQNGYDSPLD LSLGGATSAA ASAAAAASAV 300
  301 SRRRGRTYSG TESDDSAQCE RARMRLKPER KAERSAAYKK SLMKRYYTEI PIVKQSTSPA 360
  361 PQQQLQQQHH LQQQQQQQPH NGSTFAGATA LLHIKTEQNT LLTPLQLQQQ QQQQQGLHGA 420
  421 AGNGGSSNGN NAHQQQQPLA IPQRPLLHNL LSGGAIHNPH HRNYTTATTG SFPPSPADSG 480
  481 VSDVDSSSSG GQPCADELKA RLGMPPATSA SAAAAAAAAA AAAAHLHTGT FLHPNLYQNN 540
  541 AANSLRNIWN RSVGVPDNYY GSSGAGSGGT QPGGPGNPQT PGYLTTSYFN APTAATAAAS 600
  601 QRGTTINGYH SLHQQQQQQQ QSQQSQQQQQ LAHQQLSHQQ QQALHQQLSH QQQQQQQQQQ 660
  661 QHPHSQLNGP HPHSHPHSHP HSHPHAGQHT HSTIAAAAAA AAASVVSSSS SAVAAAAMLS 720
  721 ASAAAAATAA AAAGGSQSVI QPATSSVSYD LSYMLELGGF QQRKAKKPRK PKLEMGVKRR 780
  781 SREGSTTYLW EFLLKLLQDR EYCPRFIKWT NREKGVFKLV DSKAVSRLWG MHKNKPDMNY 840
  841 ETMGRALRYY YQRGILAKVD GQRLVYQFVD VPKDIIEIDC NGV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Eip74EF-PD, Eip7...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: