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Protein Overview: gnu-PA

General Information:
Name(s) found: gnu-PA / FBpp0075447 [FlyBase]
Description(s) found:
Found 38 descriptions.
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  • The gene giant nuclei is referred to in FlyBase by the symbol Dmel\gnu (CG5272, FBgn0001120). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14795480..14796457. It has the cytological map location 70F6. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitosis; regulation of cell cycle; negative regulation of DNA replication; egg activation. 13 alleles are reported. The phenotypes of these alleles are annotated with: ovary; cleavage stage embryo; cleavage nucleus. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 240 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    cytoplasm [NAS]
    Biological Process: mitosis [IGI][IMP][NAS][TAS]
    negative regulation of DNA replication [IMP][NAS]
    regulation of cell cycle [IMP][TAS]
    egg activation [IMP]
    regulation of mitotic cell cycle [TAS]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERYNRVYRD PASPLTPLTP LSTEAFTFED VTPTGGVGRK GTARYGLFGM PKNNNLTVPN  60
   61 SRPALSGLKR LSESTLPRRF SQKFMRTRSV FSPTSQSTLI NGETRLLGES GDSKLLRTKR 120
  121 EDRPKPDIRL QQETRLRQEE SKLKSARKIK VEDPRSPTPS IHHSRYKPCS PVEHPTLSPR 180
  181 VKSLLDRTGN AHLTELFTRQ EIDIEVLIQM TLEDLAALGV RGAREIRLAM NIIQLAKQFF 240
  241

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..154] FFAS03 3.34 Solution structure of PDZ domain of mouse Alpha-actinin-2 associated LIM protein
    2 View Details [155..240] Pfam 11.455932 No description for PF07647.8 was found. Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  3.13429174152905 bayes_pls_golite062009
  • protein binding
    		•  2.17099732113956 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.93452329355776 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.354842441321404 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle