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Protein Overview: UbcD4-PA, FBpp03...

General Information:
Name(s) found: FBpp0311673 [FlyBase]
FBpp0311672 [FlyBase]
UbcD4-PA / FBpp0076124 [FlyBase]
Description(s) found:
Found 36 descriptions.
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  • type=protein; loc=3L:join(9691793..9691855,9692066..9692218,9692446..9692829); ID=FBpp0311673; name=UbcD4-PC; parent=FBgn0015321,FBtr0345604; dbxref=FlyBase:FBpp0311673,FlyBase_Annotation_IDs:CG8284-PC; MD5=7b1cf870e1bb36608234e40f748959de; length=199; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3L:join(9691793..9691855,9692066..9692218,9692446..9692829); ID=FBpp0311672; name=UbcD4-PB; parent=FBgn0015321,FBtr0345603; dbxref=FlyBase:FBpp0311672,FlyBase_Annotation_IDs:CG8284-PB; MD5=7b1cf870e1bb36608234e40f748959de; length=199; release=r5.56; species=Dmel; [FlyBase]
  • The gene Ubiquitin conjugating enzyme 4 is referred to in FlyBase by the symbol Dmel\UbcD4 (CG8284, FBgn0015321). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9691442..9693581. It has the cytological map location 67C5. It is reported to have molecular function</span>: ubiquitin-protein ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: post-translational protein modification; regulation of protein metabolic process. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 199 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of protein metabolic process [IEA]
    post-translational protein modification [IEA]
    Molecular Function: ubiquitin-protein ligase activity [NAS]
    small conjugating protein ligase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANMAVSRIK REFKEVMRSE EIVQCSIKIE LVNDSWTELR GEIAGPPDTP YEGGKFVLEI  60
   61 KVPETYPFNP PKVRFITRIW HPNISSVTGA ICLDILKDNW AAAMTLRTVL LSLQALLAAA 120
  121 EPDDPQDAVV AYQFKDKYDL FLLTAKHWTN AYAGGPHTFP DCDSKIQRLR DMGIDEHEAR 180
  181 AVLSKENWNL EKATEGLFS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..199] PSI-BLAST 54.69897 Ubiquitin-conjugating enzyme E2-25 kDa (Huntington interacting protein 2)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  11.3486134076304 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  11.2964721480824 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  10.2401422444624 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  8.93602533934698 bayes_pls_golite062009
  • ligase activity
    		•  5.17219147802758 bayes_pls_golite062009
  • peptidase activity
    		•  4.11397638448668 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  3.93085931991298 bayes_pls_golite062009
  • hydrolase activity
    		•  2.88846002372004 bayes_pls_golite062009
  • SH2 domain binding
    		•  2.03311435063068 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.9559492182519 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.83472092683523 bayes_pls_golite062009
  • protein binding
    		•  1.77678273247394 bayes_pls_golite062009
  • DNA binding
    		•  1.77393825735008 bayes_pls_golite062009
  • binding
    		•  1.75350658654805 bayes_pls_golite062009
  • transcription activator activity
    		•  1.19240180311941 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.905654666464382 bayes_pls_golite062009
  • catalytic activity
    		•  0.891402822028799 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.843488104298821 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  0.715654744941217 bayes_pls_golite062009
  • damaged DNA binding
    		•  0.68887454730296 bayes_pls_golite062009
  • kinase binding
    		•  0.643955694307168 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  0.59805675560068 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.58835335751383 bayes_pls_golite062009
  • kinase activity
    		•  0.519703305315987 bayes_pls_golite062009
  • protein kinase activity
    		•  0.443948654247666 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  0.387487703339719 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.373779304908933 bayes_pls_golite062009
  • protein kinase binding
    		•  0.235250314885345 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.182854082413338 bayes_pls_golite062009
  • transferase activity
    		•  0.0984525836903841 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle