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Protein Overview: mad2-PA

General Information:
Name(s) found: mad2-PA / FBpp0076819 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene mad2 is referred to in FlyBase by the symbol Dmel\mad2 (CG17498, FBgn0035640). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:5805232..5806183. It has the cytological map location 64E11-64E12. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitotic cell cycle spindle assembly checkpoint; mitotic cell cycle checkpoint; cell cycle. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 207 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDA]
    nucleus [ISS]
    cytoplasm [IDA]
    kinetochore microtubule [IDA]
    spindle [IDA]
    kinetochore [IDA]
    Biological Process: mitotic cell cycle spindle assembly checkpoint [IDA][IMP][ISS]
    mitotic cell cycle checkpoint [IMP]
    cell cycle [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAQATKNC ITLKGSAQII VEYLKYGINS ILFQRGIYPA EDFNNTQQYG LTILMSKDPK  60
   61 IKTFLQNVLS QTEEWLSKNM INKISMVITN AHTKEVLECW DFNMQAELGD GDISDPTKAT 120
  121 TTKELSRIQN EIRDVMRQIS ATVSYLPLLD CICTFDIMIH TLQNTELPAK WDETGAIVIQ 180
  181 NPQAVQLRSF STGLHKVDTV VNYKMST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..207] PSI-BLAST 68.69897 The Mad2 spindle checkpoint protein possesses two distinct natively folded states

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.14424444268625 bayes_pls_golite062009
  • protein binding
    		•  0.856075580719879 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle