YRC Public Data Repository - Protein Structure Prediction

Protein:	mad2-PA
Organism:	Drosophila melanogaster
Length:	207 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mad2-PA.

Description	E-value	Query Range	Subject Range
gi\|157819417, gi... - gi\|27711040\|ref\|XP_216161.1\| PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A...	259.0	[0..1]	[204..1]
gi\|73983524 - gi\|73983524\|ref\|XP_533278.2\| PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A...	259.0	[0..1]	[207..1]
gi\|190689935, gi... - gi\|190691307\|gb\|ACE87428.1\| MAD2 mitotic arrest deficient-like 1 (yeast) protein [synthetic construc... gi\|67969313 - gi\|67969313\|dbj\|BAE01009.1\| unnamed protein product [Macaca fascicularis] MAD2L1 - MAD2 mitotic arrest deficient-like 1 (yeast) ENSCJAT00000006092 - null ENSPTRT00000030501 - null ENSMMUT000000068... - null, null	258.0	[0..1]	[205..1]
gi\|61365562, gi\|... - gi\|61365562\|gb\|AAX42727.1\| MAD2 mitotic arrest deficient-like 1 [synthetic construct], gi\|54696400\|g...	258.0	[0..1]	[205..1]
gi\|115390332, gi... - gi\|115390332\|ref\|XP_001212671.1\| mitotic spindle checkpoint component mad2 [Aspergillus terreus NIH2...	258.0	[0..1]	[206..1]
MD2L1_MOUSE - Mitotic spindle assembly checkpoint protein MAD2A OS=Mus musculus GN=Mad2l1 PE=1 SV=2	258.0	[0..1]	[204..1]

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Predicted Domain #1

Region A:
Residues: [1-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAQATKNC ITLKGSAQII VEYLKYGINS ILFQRGIYPA EDFNNTQQYG LTILMSKDPK  60
   61 IKTFLQNVLS QTEEWLSKNM INKISMVITN AHTKEVLECW DFNMQAELGD GDISDPTKAT 120
  121 TTKELSRIQN EIRDVMRQIS ATVSYLPLLD CICTFDIMIH TLQNTELPAK WDETGAIVIQ 180
  181 NPQAVQLRSF STGLHKVDTV VNYKMST

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.69897
Match:	1s2hA
Description:	The Mad2 spindle checkpoint protein possesses two distinct natively folded states
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.14424444268625	bayes_pls_golite062009
protein binding	0.856075580719879	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: