YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: CG5602-PA

General Information:
Name(s) found: CG5602-PA / FBpp0072041 [FlyBase]
Description(s) found:
Found 20 descriptions.
SHOW ALL
  • This gene is referred to in FlyBase by the symbol Dmel\CG5602 (CG5602, FBgn0034922). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19778061..19780700. It has the cytological map location 60A8. Based on sequence similarity, it is predicted to have molecular function</span>: DNA ligase (ATP) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: DNA recombination; DNA repair; DNA replication. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 747 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: DNA repair [IEA]
    DNA replication [IEA]
    DNA recombination [IEA]
    Molecular Function: DNA binding [IEA]
    ATP binding [IEA]
    DNA ligase (ATP) activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKSITSFFK KKSDATDSPS PPKKVPKIDA KTELPDEPHI KSESASPETK PKVEPMSVDS  60
   61 EEKTSPVKNV KKEPKEVDDK TTDKKVTTIG LNSTAATKED VENYDPSADS YHPLKNAYWK 120
  121 DKKVTPYLAL ARTFQVIEET KGRLKMIDTL SNFFCSVMLV SPEDLVPSVY LSINQLAPAY 180
  181 EGLELGVAET TLMKAICKAT GRNLAHIKSQ TQLTGDLGIV AEQSRVSQRM MFQPAPLNVR 240
  241 DVFRKLREIA KLSGQSKMDL VYNMFVACRS SEARFFIRSL IGKLRIGIAE QSLLTALAIG 300
  301 LVKKNHIDDC KASKVPDVYK DEIVDTTLLL KTAYCQCPNY DIIIPAILKY DIKELQERCP 360
  361 MHPGMPLRPM LAQPTKGVHE VFERFGGMQI TCEWKYDGER AQIHRNEKGE ISIFSRNSEN 420
  421 NTAKYPDLIA RSTALLKGDV KSYIIDSEIV AWDVERKQIL PFQVLSTRKR KNVDIEEIKV 480
  481 QVCVYIFDLL YINGTALVTK NLSERRKLLL EHFQEVEGEW KFATALDTND IDEVQQFLEE 540
  541 SIKGNCEGLM VKTLDEEATY EIAKRSRNWL KLKKDYLSNV GDSLDLVVIG GYKGKGRRTG 600
  601 TYGGFLLACY DTENEEYQSI CKIGTGFTDE DLQTHSEFLG KHVTSAAKSY YRYDPSLEPD 660
  661 HWFEPVQVWE VKCADLSLSP IHRAAIGIVD GERGISLRFP RFIRIRDDKN SENATDANQV 720
  721 AHMYQSQDQV KNNQKSSTQM EMEDEFY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..64] PSI-BLAST 4.09691 Solution structure of the zinc-finger domain from DNA ligase IIIa
    2 View Details [65..747] PSI-BLAST 177.0 Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  1.10126761346723 bayes_pls_golite062009
  • binding
    		•  1.03163529784653 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.83578688346684 bayes_pls_golite062009
  • DNA binding
    		•  0.78991420977701 bayes_pls_golite062009
  • catalytic activity
    		•  0.472235543748473 bayes_pls_golite062009
  • protein binding
    		•  0.423719585823079 bayes_pls_golite062009
  • transcription factor activity
    		•  0.29405007637982 bayes_pls_golite062009
    2
    Term Confidence Notes
  • ligase activity, forming phosphoric ester bonds
    		•  4.3248432594553 bayes_pls_golite062009
  • DNA ligase activity
    		•  4.32201730952065 bayes_pls_golite062009
  • DNA ligase (NAD+) activity
    		•  3.23439045843438 bayes_pls_golite062009
  • catalytic activity
    		•  2.52414801555837 bayes_pls_golite062009
  • ligase activity
    		•  1.91469215096842 bayes_pls_golite062009
  • DNA ligase (ATP) activity
    		•  1.83677193007569 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle