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Protein Overview: CG10082-PB

General Information:
Name(s) found: CG10082-PB / FBpp0071579 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG10082 (CG10082, FBgn0034644). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17533683..17544944. It has the cytological map location 57F6. Based on sequence similarity, it is predicted to have molecular function</span>: inositol or phosphatidylinositol kinase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: protein amino acid phosphorylation; phosphatidylinositol metabolic process. 13 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 672 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISS]
    Biological Process: phosphatidylinositol metabolic process [ISS]
    protein amino acid phosphorylation [ISS]
    Molecular Function: inositol or phosphatidylinositol kinase activity [ISS]
    inositol trisphosphate 3-kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVMQATTMG GAKLDKRYSP SFRDDAAAVP VRKMSASKRK RDEVLRMKVH KNGQAAEVIK  60
   61 SISQLDNTNK QYFLMLENIT SQFRNPCILD LKMGTRQHGD DASAEKRSKQ MAKCAASTSG 120
  121 SLGVRLCGMQ TYLADLEQYA KRDKYWGREL NEGGFKTALH DFFHNGYRLR IRVIRKILQR 180
  181 LLQLRRVIEK QSSYRFYSCS LLIVYEGFEE NPMAPPPSMS QDEWPEAPRS ATVPGTVFDY 240
  241 HPENSIDEDD LEDDDEAGNE AGDELEAHDT DDDLHLVAAD SGNASATNSS TGGDACNYDA 300
  301 DASNDSNSLL NLATRRHLHK RGFAEAAARG VKQTASHNTT TDEEEEDEHP AMPPPRTCGV 360
  361 MAAKAAAAAA GLAGKGQGAF IPISEETVFL DPEPALPSVT TSSPHSGDSW MNYSSNSSDD 420
  421 FSGLSEQIKA VASGRQTCNN SSDDASSDYE SSIIGPTEAM FKRYKSQQSF DAATAADSAS 480
  481 SPPLTAGNSS VSNGGTTVRS LVSPASSSAS SLKSVKGAVK RLRCNDDDQQ SASLGESDLR 540
  541 EAKKSTITST PVSAVSSPAK AAPQLRSCES ISNQQSLLSG LLLDNNNEQR RNALLQQSSK 600
  601 SLDMSAPPTD DNQCFVDVRL IDFAHTAFVP RNGTMLPTPA AAPVHHGPDG GFLTGLDSLN 660
  661 RLLNEIVAEE RA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..260] PSI-BLAST 71.30103 Crystal Structure of the Catalytic and CaM-Binding domains of Inositol 1,4,5-Trisphosphate 3-Kinase B
    2 View Details [261..334] PSI-BLAST 11.0 Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS)
    3 View Details [335..672] FFAS03 1.56 Human Inositol (1,4,5)-trisphosphate 3-kinase substituted with selenomethionine

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • inositol or phosphatidylinositol kinase activity
    		•  3.47657203297846 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  3.34794389409016 bayes_pls_golite062009
  • kinase activity
    		•  3.17803153508283 bayes_pls_golite062009
  • lipid kinase activity
    		•  2.86902735212205 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.82284338932364 bayes_pls_golite062009
  • phosphatidylinositol phosphate kinase activity
    		•  2.47188940728988 bayes_pls_golite062009
  • 1-phosphatidylinositol-4-phosphate 5-kinase activity
    		•  1.95599290202476 bayes_pls_golite062009
  • transferase activity
    		•  1.78825635695115 bayes_pls_golite062009
  • catalytic activity
    		•  1.73183773103487 bayes_pls_golite062009
  • protein kinase activity
    		•  1.20409118476111 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  1.08715556631765 bayes_pls_golite062009
  • ligase activity
    		•  0.798603980757376 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.727802848908001 bayes_pls_golite062009
  • protein binding
    		•  0.529824674868566 bayes_pls_golite062009
  • binding
    		•  0.467338981759371 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle