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View Structure Prediction Details

Protein: CG10082-PB
Organism: Drosophila melanogaster
Length: 672 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG10082-PB.

Description E-value Query
Range
Subject
Range
CG10082-PA - This gene is referred to in FlyBase by the symbol Dmel\CG10082 (CG10082, FBgn0034644). It is a prote...
367.0 [0..2] [672..232]

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Predicted Domain #1
Region A:
Residues: [1-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVMQATTMG GAKLDKRYSP SFRDDAAAVP VRKMSASKRK RDEVLRMKVH KNGQAAEVIK  60
   61 SISQLDNTNK QYFLMLENIT SQFRNPCILD LKMGTRQHGD DASAEKRSKQ MAKCAASTSG 120
  121 SLGVRLCGMQ TYLADLEQYA KRDKYWGREL NEGGFKTALH DFFHNGYRLR IRVIRKILQR 180
  181 LLQLRRVIEK QSSYRFYSCS LLIVYEGFEE NPMAPPPSMS QDEWPEAPRS ATVPGTVFDY 240
  241 HPENSIDEDD LEDDDEAGNE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.30103
Match: 2aqxA
Description: Crystal Structure of the Catalytic and CaM-Binding domains of Inositol 1,4,5-Trisphosphate 3-Kinase B
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [261-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGDELEAHDT DDDLHLVAAD SGNASATNSS TGGDACNYDA DASNDSNSLL NLATRRHLHK  60
   61 RGFAEAAARG VKQT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 1xd4A
Description: Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [335-672]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASHNTTTDEE EEDEHPAMPP PRTCGVMAAK AAAAAAGLAG KGQGAFIPIS EETVFLDPEP  60
   61 ALPSVTTSSP HSGDSWMNYS SNSSDDFSGL SEQIKAVASG RQTCNNSSDD ASSDYESSII 120
  121 GPTEAMFKRY KSQQSFDAAT AADSASSPPL TAGNSSVSNG GTTVRSLVSP ASSSASSLKS 180
  181 VKGAVKRLRC NDDDQQSASL GESDLREAKK STITSTPVSA VSSPAKAAPQ LRSCESISNQ 240
  241 QSLLSGLLLD NNNEQRRNAL LQQSSKSLDM SAPPTDDNQC FVDVRLIDFA HTAFVPRNGT 300
  301 MLPTPAAAPV HHGPDGGFLT GLDSLNRLLN EIVAEERA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.56
Match: 1w2fA
Description: Human Inositol (1,4,5)-trisphosphate 3-kinase substituted with selenomethionine
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
inositol or phosphatidylinositol kinase activity 3.47657203297846 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 3.34794389409016 bayes_pls_golite062009
kinase activity 3.17803153508283 bayes_pls_golite062009
lipid kinase activity 2.86902735212205 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.82284338932364 bayes_pls_golite062009
phosphatidylinositol phosphate kinase activity 2.47188940728988 bayes_pls_golite062009
1-phosphatidylinositol-4-phosphate 5-kinase activity 1.95599290202476 bayes_pls_golite062009
transferase activity 1.78825635695115 bayes_pls_golite062009
catalytic activity 1.73183773103487 bayes_pls_golite062009
protein kinase activity 1.20409118476111 bayes_pls_golite062009
acid-amino acid ligase activity 1.08715556631765 bayes_pls_golite062009
ligase activity 0.798603980757376 bayes_pls_golite062009
protein serine/threonine kinase activity 0.727802848908001 bayes_pls_golite062009
protein binding 0.529824674868566 bayes_pls_golite062009
binding 0.467338981759371 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle