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Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate. Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP. Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: inositol trisphosphate 3-kinase activity
Acc: GO:0008440
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.
Synonyms:
  • 1D-myo-inositol-trisphosphate 3-kinase activity
  • ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase activity
  • Ins(1,4,5)P3 3-kinase activity
  • inositol 1,4,5-trisphosphate 3-kinase activity
  • inositol-trisphosphate 3-kinase activity
  • ins(1,4,5)P(3) 3-kinase activity
  • IP3 3-kinase activity
  • IP3K activity
Proteins in PDR annotated with:
   This term: 37 [Search]
   Term or descendants: 37 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008440 - inositol trisphosphate 3-kinase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle