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Protein Overview: CG7813-PA

General Information:
Name(s) found: CG7813-PA / FBpp0086272 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG7813 (CG7813, FBgn0034133). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12384394..12386934. It has the cytological map location 53C6. Based on sequence similarity, it is predicted to have molecular function</span>: hydrogen-exporting ATPase activity, phosphorylative mechanism. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ATP synthesis coupled proton transport. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 734 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [IEA]
    mitochondrial proton-transporting ATP synthase complex [ISS]
    Biological Process: ATP synthesis coupled proton transport [IEA]
    Molecular Function: hydrogen-exporting ATPase activity, phosphorylative mechanism [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWEKLVNCIK SNGGNGGVKN VSCQVVELAD LMKQVPPNQM HKFKMFAKKH EEYKDRVRKY  60
   61 PESMPTIDWE YYRQNVREEF VDWVKGYETK YDKLHSVFEN RHAIVDHKRY FELVDEEKKV 120
  121 VTKCISEYKA ESDKRIQELT EKLEFVKAMR PYSEMTMEEF CFARPHLAPD FINKPTFWPH 180
  181 TPEEQMPGPS DPEAAAALHH EEEPEPPKKP APEKLPDKPS GEGKPPAAAA PKEPKEPVVD 240
  241 TSQLAEKATL IAKDLMAKAI VLFNSLKEKM SGLAKNVQKK ADAAKAARSE TASKSATPTA 300
  301 APTKSLDSIT ERESGPNICN QTIIRSEEAE ANPEVKARHT NLSIEADPCD AQEERAREIA 360
  361 RTLERKRQLK EAEEWEKHKT KKDPCDAEKE TDPCKLMEEE TVCKPDPCKA KEEEAVCKPD 420
  421 PCQQKEKEDD ICKPDPCKPK DEEGSCEDEE DPCKKKPKCD GDYQFGGDNE GGSTKSKQQD 480
  481 QVFINISECS KELAKQEEKK SGDSGKPKEK ASLSEIPQGS DQKPVLGMQI TESKDSKKDH 540
  541 KASIEGANEI GPVYTDPNQL AELLVQKKEK PVIIEEAQKP EDDKPITIYP KLEISANPKG 600
  601 DQVKQEAEGQ KSPKDMAKQV FTMASGAATL LTEATNTLED LKRKKEARLE ALEQAYTSAQ 660
  661 RQAQGALAEA SKAVEAANNL AIRSAEQTGE VSSRDREALE MAEKHAILAK MLAGRAVALK 720
  721 DEIARVLKDL KKKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..213] FFAS03 4.83 No description for 2clyB was found.
    2 View Details [214..394] deduced N/A No confident structure predictions are available.
    3 View Details [395..618] MSA 1.200991 View MSA. No confident structure predictions are available.
    4 View Details [619..734] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrogen ion transmembrane transporter activity
    		•  10.4771740280281 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  8.74387075467203 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  7.71288270107263 bayes_pls_golite062009
  • hydrogen-exporting ATPase activity, phosphorylative mechanism
    		•  5.74651481307439 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.06520805801627 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.00303078124004 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.6568834630265 bayes_pls_golite062009
  • transporter activity
    		•  2.09446909453822 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.95143742089762 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.85760800452121 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
    		•  1.71724018787703 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.55719634624148 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.33962435158626 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.27705194692065 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.26107190618552 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.25868392573364 bayes_pls_golite062009
  • ATPase activity
    		•  1.23179925941624 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.750078360675383 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.743376850589954 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.725518597573098 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.713153844911386 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.709627367159007 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.709624804677536 bayes_pls_golite062009
  • catalytic activity
    		•  0.522768476788318 bayes_pls_golite062009
  • hydrolase activity
    		•  0.400445642436741 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  0.299031083632482 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle