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View Structure Prediction Details

Protein: CG7813-PA
Organism: Drosophila melanogaster
Length: 734 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG7813-PA.

Description E-value Query
Range		 Subject
Range
gi|70878483 - gi|70878483|gb|EAN91735.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71649745 - gi|71649745|ref|XP_813586.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
 324.0 [0..3] [733..856]

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Predicted Domain #1
Region A:
Residues: [1-213] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWEKLVNCIK SNGGNGGVKN VSCQVVELAD LMKQVPPNQM HKFKMFAKKH EEYKDRVRKY  60
   61 PESMPTIDWE YYRQNVREEF VDWVKGYETK YDKLHSVFEN RHAIVDHKRY FELVDEEKKV 120
  121 VTKCISEYKA ESDKRIQELT EKLEFVKAMR PYSEMTMEEF CFARPHLAPD FINKPTFWPH 180
  181 TPEEQMPGPS DPEAAAALHH EEEPEPPKKP APE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.83
Match: 2clyB
Description: No description for 2clyB was found.

Predicted functions:

Term Confidence Notes
hydrogen ion transmembrane transporter activity 10.4771740280281 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 8.74387075467203 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 7.71288270107263 bayes_pls_golite062009
hydrogen-exporting ATPase activity, phosphorylative mechanism 5.74651481307439 bayes_pls_golite062009
cation transmembrane transporter activity 4.06520805801627 bayes_pls_golite062009
ion transmembrane transporter activity 4.00303078124004 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.6568834630265 bayes_pls_golite062009
transporter activity 2.09446909453822 bayes_pls_golite062009
transmembrane transporter activity 1.95143742089762 bayes_pls_golite062009
substrate-specific transporter activity 1.85760800452121 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 1.71724018787703 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.55719634624148 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.33962435158626 bayes_pls_golite062009
pyrophosphatase activity 1.27705194692065 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.26107190618552 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.25868392573364 bayes_pls_golite062009
ATPase activity 1.23179925941624 bayes_pls_golite062009
primary active transmembrane transporter activity 0.750078360675383 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.743376850589954 bayes_pls_golite062009
active transmembrane transporter activity 0.725518597573098 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.713153844911386 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.709627367159007 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.709624804677536 bayes_pls_golite062009
catalytic activity 0.522768476788318 bayes_pls_golite062009
hydrolase activity 0.400445642436741 bayes_pls_golite062009
ATPase activity, coupled 0.299031083632482 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [214-394] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLPDKPSGEG KPPAAAAPKE PKEPVVDTSQ LAEKATLIAK DLMAKAIVLF NSLKEKMSGL  60
   61 AKNVQKKADA AKAARSETAS KSATPTAAPT KSLDSITERE SGPNICNQTI IRSEEAEANP 120
  121 EVKARHTNLS IEADPCDAQE ERAREIARTL ERKRQLKEAE EWEKHKTKKD PCDAEKETDP 180
  181 C

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [395-618] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLMEEETVCK PDPCKAKEEE AVCKPDPCQQ KEKEDDICKP DPCKPKDEEG SCEDEEDPCK  60
   61 KKPKCDGDYQ FGGDNEGGST KSKQQDQVFI NISECSKELA KQEEKKSGDS GKPKEKASLS 120
  121 EIPQGSDQKP VLGMQITESK DSKKDHKASI EGANEIGPVY TDPNQLAELL VQKKEKPVII 180
  181 EEAQKPEDDK PITIYPKLEI SANPKGDQVK QEAEGQKSPK DMAK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [619-734] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVFTMASGAA TLLTEATNTL EDLKRKKEAR LEALEQAYTS AQRQAQGALA EASKAVEAAN  60
   61 NLAIRSAEQT GEVSSRDREA LEMAEKHAIL AKMLAGRAVA LKDEIARVLK DLKKKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle