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Protein Overview: FBpp0301623

General Information:
Name(s) found: FBpp0301623 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • type=protein; loc=2R:complement(9327577..9327833,9327897..9330021,9330439..9330633,9330959..9331197,9331258..9331321,9331393..9331611,9331680..9331847,9331933..9332199,9332270..9332643,9332716..9332770); ID=FBpp0301623; name=cnn-PJ; parent=FBgn0013765,FBtr0309889; dbxref=FlyBase:FBpp0301623,FlyBase_Annotation_IDs:CG4832-PJ,REFSEQ:NP_725298,GB_protein:AAF58376; MD5=20eeb365130d7d563087eff5d5d1349e; length=1320; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1320 amino acids

    Gene Ontology:
    Cellular Component: myosin complex [ISS]
    pericentriolar material [NAS]
    centrosome [IDA][NAS]
    cytoplasm [NAS]
    microtubule associated complex [ISS]
    Biological Process: central nervous system development [IMP]
    midgut development [IMP]
    centrosome cycle [IMP]
    mitotic spindle organization [IMP][NAS]
    nuclear division [NAS]
    peripheral nervous system development [IMP]
    microtubule cytoskeleton organization [NAS]
    female meiosis chromosome segregation [IMP]
    microtubule-based process [ISS]
    Molecular Function: microtubule binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSNRTSSSH NSRNLKILNA SFDVPRPPGG GNSPLPSQGR SVRELEEQMS ALRKENFNLK  60
   61 LRIYFLEEGQ PGARADSSTE SLSKQLIDAK IEIATLRKTV DVKMELLKDA ARAISHHEEL 120
  121 QRKADIDSQA IIDELQEQIH AYQMAESGGQ PVENIAKTRK MLRLESEVQR LEEELVNIEA 180
  181 RNVAARNELE FMLAERLESL TACEGKIQEL AIKNSELVER LEKETASAES SNEAIDSLKV 240
  241 ELEACRKENQ DLVTSIRTLK HDMKRQVRSM KEAANTMDVQ RQSILLLEAT IKRKEKSCGS 300
  301 MQKNVLNYEA LIAKLNAELE TMRQQNVYFR ELSENLQQKE VRQLDRGVAI VQPMRMTADA 360
  361 GRFVWQSGTI VAQEPLPLER QSAAATSNVS VSAVRLSSGP PPDQTYPVNG HDRAKYGLLQ 420
  421 LFAAKLDWIS AVPLALGHLA LKIILLAMRL HSCLQNVHIP LRANRDLGAQ LADKICELQE 480
  481 AQEKLKERER IHEQACRTIQ KLMQKLSSQE KEIKKLNQEN EQSANKENDC AKTVISPSSS 540
  541 GRSMSDNEAS SQEMSTNLRV RYELKINEQE EKIKQLQTEV KKKTANLQNL VNKELWEKNR 600
  601 EVERLTKLLA NQQKTLPQIS EESAGEADLQ QSFTEAEYMR ALERNKLLQR KVDVLFQRLA 660
  661 DDQQNSAVIG QLRLELQQAR TEVETADKWR LECVDVCSVL TNRLEELAGF LNSLLKHKDV 720
  721 LGVLAADRRN AMRKAVDRSL DLSKSLNMTL NITATSLADQ SLAQLCNLSE ILYTEGDASH 780
  781 KTFNSHEELH AATSMAPTVE NLKAENKALK KELEKRRSSE GQRKERRSLP LPSQQFDNQS 840
  841 ESEAWSEPDR KVSLARIGLD ETSNSLAAPE QAISESESEG RTCATRQDRN RNSERIAQLE 900
  901 EQIAQKDERM LNVQCQMVEL DNRYKQEQLR CLDITQQLEQ LRAINEALTA DLHAIGSHEE 960
  961 ERMVELQRQL ELKNQQIDQL KLAHSTLTAD SQITEMELQA LQQQMQEIEQ LHADSVETLQ1020
 1021 SQLQKLKLDA VQQLEEHERL HREALERDWV ALTTYQEQAQ QLLELQRSLD YHQENEKELK1080
 1081 QTLVENELAT RALKKQLDES TLQASKAVME RTKAYNDKLQ LEKRSEELRL QLEALKEEHQ1140
 1141 KLLQKRSNSS DVSQSGYTSE EVAVPMGPPS GQATTCKQAA AAVLGQRVNT SSPDLGIESD1200
 1201 AGRISSVEVS NAQRAMLKTV EMKTEGSASP KAKSEESTSP DSKSNVATGA ATVHDCAKVD1260
 1261 LENAELRRKL IRTKRAFEDT YEKLRMANKA KAQVEKDIKN QILKTHNVLR NVRSNMENEL1320
 1321

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..375] PSI-BLAST 31.0 Heavy meromyosin subfragment
    2 View Details [376..494] PSI-BLAST 9.154902 Tropomyosin
    3 View Details [495..833] FFAS03 1.43 Tropomyosin
    4 View Details [834..1021] PSI-BLAST 3.39794 No description for 2iw5A was found.
    5 View Details [1022..1224] PSI-BLAST 4.0 No description for 2dfsA was found.
    6 View Details [1225..1320] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • actin binding
    		•  2.52775592528812 bayes_pls_golite062009
  • binding
    		•  2.45058468282438 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.1457670954804 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09157817179555 bayes_pls_golite062009
  • DNA binding
    		•  2.02150889787803 bayes_pls_golite062009
  • transcription factor activity
    		•  1.63173451778586 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.27419374347122 bayes_pls_golite062009
  • actin filament binding
    		•  1.22830639594779 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.19342126720259 bayes_pls_golite062009
  • protein binding
    		•  0.853351196918381 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.82709508945531 bayes_pls_golite062009
  • transcription activator activity
    		•  0.18183175007284 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.16239538021276 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle