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Protein Overview: Aats-val-PA, Aat...

General Information:
Name(s) found: Aats-val-PA / FBpp0086848 [FlyBase]
Aats-val-PB / FBpp0086847 [FlyBase]
Description(s) found:
Found 34 descriptions.
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  • The gene Valyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\Aats-val (CG4062, FBgn0027079). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9086356..9090217. It has the cytological map location 49F7. Based on sequence similarity, it is predicted to have molecular function</span>: glutamate-tRNA ligase activity; valine-tRNA ligase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: valyl-tRNA aminoacylation. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Valyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\Aats-val (CG4062, FBgn0027079). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9086356..9090217. It has the cytological map location 49F7. Based on sequence similarity, it is predicted to have molecular function</span>: glutamate-tRNA ligase activity; valine-tRNA ligase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: valyl-tRNA aminoacylation. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1049 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: valyl-tRNA aminoacylation [ISS]
    Molecular Function: valine-tRNA ligase activity [ISS]
    ATP binding [IEA]
    glutamate-tRNA ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEAEQQNDA NAPAGAGGDP PKTAKQLEKE RLKAEKLAKL QAKLDKKAAA APAAGEKKEK  60
   61 PEKRTKEVKE AAVYTAQTAP GEKKDLSGAL PDAYSPRYVE AQWYSWWEKE GFFTPEYGRA 120
  121 SIDAPNPNGK FVMIIPPPNV TGSLHLGHAL TNAIEDAITR YHRMKGRTTL WVPGCDHAGI 180
  181 ATQVVVEKLL WRDEKLSRHD LGREKFIERI WDWRREKGGR IYEQLKSLGS SYDWTRVAFT 240
  241 MDPKLCRAVT EAFVRLHEEG SIYRSSRLVN WSCTLRSAIS DIEVDKVEIP GRTFLSIPGY 300
  301 EDKVEFGVLI KFAYKVEGSD EEIIVATTRI ETMLGDTAVA VHPQDDRYKH LHGKFVVHPF 360
  361 STRRLPIVCD EFVDMAFGTG AVKITPAHDP NDYEVGKRCN LPFITIFNDD GYIIGDYGEF 420
  421 TGMKRFECRK KILEKLKALN LYRETLNNPM VVPICSRSKD VVEPLIKPQW YVSCSDMAAS 480
  481 ATEAVRSGEL KIIPEHHTKT WYHWMDGIRD WCVSRQLWWG HRIPAYHVSF TDPSLQTGSN 540
  541 DDEQYWIVAR SEAEALTKAA ERFGVDASKI VLKQDEDVLD TWFSSGIFPF SVFGWPDQTK 600
  601 DLQTFYPTSL LETGHDILFF WVARMVFFGQ KLLGKLPFKE VYLHPMVRDA HGRKMSKSLG 660
  661 NVIDPMDVIR GITLEGLHAQ LVGSNLDPRE IEKAKAGQKQ DYPQGIPECG SDALRFALCA 720
  721 YITQARDINL DINRVLGYRF FCNKLWNATK FALLYFTGSE KFDTELSASA AINQMDAWIL 780
  781 SRLAAAIEAC NTGFESYDFA AATSACYAFW LYDLCDVYLE CLKPIFQSGS EEQQTAARRT 840
  841 LYVCLDYGLR LLSPFMPFIT EELYQRLPRA NPAPSICVAS YPSNTSWRST KIESDVEFVQ 900
  901 KAARIIRSAR SDYNLPNKVK TEVYIVCTDS VPSEILKRYA SDLATISYCS NVVFDSPAPQ 960
  961 GCAILTVTGQ CEVHLLLKGL VEADKEIAKL QKKSDQLVQT VGKLTQAIQA ADYATKVPAE1020
 1021 VQEANETKLC ESRAEIERIA AAIETLKLM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] deduced N/A No confident structure predictions are available.
    2 View Details [88..1049] PSI-BLAST 1000.0 Valyl-tRNA synthetase (ValRS) C-terminal domain; Valyl-tRNA synthetase (ValRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • valine-tRNA ligase activity
    		•  7.13767629265822 bayes_pls_golite062009
  • leucine-tRNA ligase activity
    		•  7.03538514482698 bayes_pls_golite062009
  • isoleucine-tRNA ligase activity
    		•  6.38633897147986 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.56893064485672 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.50161401062914 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • binding
    		•  0.485102284225571 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.449504767632354 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.2293846471193 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle