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Protein Overview: sns-PA

General Information:
Name(s) found: sns-PA / FBpp0087716 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene sticks and stones is referred to in FlyBase by the symbol Dmel\sns (CG33141, FBgn0024189). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4686022..4743142. It has the cytological map location 44F1. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: myoblast fusion; larval visceral muscle development; heterophilic cell adhesion; garland cell differentiation. 53 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; anatomical structure; primordium; garland cell; late extended germ band embryo; myoblast; embryonic/larval garland cell; midgut constriction; circular visceral muscle fiber; adult segment. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1479 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA][ISS]
    Biological Process: myoblast fusion [IMP][TAS]
    heterophilic cell-cell adhesion [IMP]
    cell adhesion [ISS]
    garland cell differentiation [IMP]
    larval visceral muscle development [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALQQQHQRH QQHQQHQQQQ QQQQQQQHIK WQQHATKRRR CRQHWIKHLQ LLRLLAVIVL  60
   61 ASAPVPSHAQ QQKFRTTPHD LQVLEGAEAM MRCEVANVAG AVQWTKDGFA LGFSAVIPGF 120
  121 PRYSVLGDRK QGIYNLRISN ASINDDADYQ CQVGPARLNS AIRANAKLTV ISPPASIEIK 180
  181 GYSHNSKVEV RENQDLQLKC IVANAKPAAQ IVWYRGNVEY KPEKREDTVE ESTAKRFTTT 240
  241 SSLKLKPGPD DDYTEYTCQA RHKALSPDMP MRATVQLSVL YPPGPPYIEG YSAGETLRRG 300
  301 QTVELMCRSR GGNPPAQLIW YKNGSQIRMA YRTSGRLSEN IYTFTAEAGD NKARFRCEAS 360
  361 NVMSQNPLKA EVELSVLFAP THVTVMGPTE ARVGDIVPLT CTTAPSNPPA EIKWMVGGRQ 420
  421 VRNATSKTIV SPEGGWTTTS NITAVVEPNK RSLVVICHGL NMQLTENVVS THTINVLYPP 480
  481 APPLISGYME GQIIPAGSVQ KLLCVSSGGN PLATLTWYKN DKRINSVIRA ADKSVSAEIT 540
  541 ILANVSDNQA QYRCEASNSA TEIPLFQSTT LSVHFAPETV KIRIEPEELR PGMEATIICD 600
  601 SSSSNPPAKL SWWKDGIPIE GINNTSKPGL WGGTVSTLEF RVNVTQEMNG QVYTCQSANE 660
  661 ALQRSAHEAV SLDVLYRPKF VPPPSSTAVG VEGESLQVSL QTRANPTPVT YKWTKDGTTI 720
  721 PQDGDHRIFA DGGSLNFTRL HRDDAGIYSC SASNSQGGAT LNITVVVEYG TTIKSVSENI 780
  781 VVNPGEDAML SCTVEGKPLT EEHVKWERVG YDMTVKTSTT FANGTSYLHI KDAKREDVGN 840
  841 FRCVADNRVD NPTNRDILLI VKFAPEIAKT PTLLRAASGT GERGRLPCRA QGSPKPQFIW 900
  901 RQDKKDLPIN RTYKYEVEER KIDSLTYEST LIVDKVAPAD YGAYECVARN ELGEAVETVR 960
  961 LEITSQPDPP LSLNILNVTH DTVTLAWTPG FDGGLKASYR VRYRMADREQ YKYIDGLPNS1020
 1021 HKLTIGGLRM NTLYLFSVMS WNELGQSSYL PDLARAETKG LELMPAELTE DSSNTPNLVI1080
 1081 IGISLAAFGF LLVNASLVAW FFVHQRRKKV AETTNQPAKT ATIEMYAPSS YNDTVTGETL1140
 1141 SSVSEKSESY SNEGSSQPEY IDEVRKKAAS TYLVEGSDMP PPRYQKDGTL PVIYPNNVVN1200
 1201 ACTLPHPRHN NGSAAIHMTR DDQMLISKGV YIPSPSPAPP PDGSYYNMNS DRYLSYPPME1260
 1261 YPAALDFTAQ PMPMAHLQPM TVTSLATNGG PTLIGNGSVA AVAGGSGTLR RGILRGVVGV1320
 1321 PQPDVTHHTS TVGGSPMQML HDLHPVNLSA STLTTSTTLN GSLPTATATL PRQPHGILKD1380
 1381 PNRNKQQQQQ QQQQQQQQQL QHQQQLLNAS LVGVGVPVSA PLGSLQILNL PPASGGLGNN1440
 1441 LLMTTNAFDP TTVGLSSFGA VSQAGGIPVA YTDADGHLV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..206] PSI-BLAST 25.69897 ENAIIHis Fab fragment in the free form
    2 View Details [207..846] PSI-BLAST 64.0 Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data
    3 View Details [847..1061] PSI-BLAST 35.69897 No description for 2nziA was found.
    4 View Details [1062..1178] PSI-BLAST 17.154902 Integin beta-4 subunit
    5 View Details [1179..1346] deduced N/A No confident structure predictions are available.
    6 View Details [1347..1479] PSI-BLAST 10.522879 Solution structure of the eighth Ig-like domain of human myosin light chain kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • antigen binding
    		•  6.15874156332332 bayes_pls_golite062009
  • receptor activity
    		•  3.17924100507291 bayes_pls_golite062009
  • signal transducer activity
    		•  3.10913345555941 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.10913345555941 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  2.91032591770004 bayes_pls_golite062009
  • binding
    		•  2.74708244886154 bayes_pls_golite062009
  • protein binding
    		•  2.22855404705168 bayes_pls_golite062009
  • olfactory receptor activity
    		•  2.08021142115894 bayes_pls_golite062009
  • receptor binding
    		•  1.70260377709721 bayes_pls_golite062009
  • peptide antigen binding
    		•  1.66960790017756 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  1.36789541796983 bayes_pls_golite062009
  • IgG binding
    		•  1.27089907020716 bayes_pls_golite062009
  • protein complex binding
    		•  1.19581190330569 bayes_pls_golite062009
  • integrin binding
    		•  0.599569390248921 bayes_pls_golite062009
  • monosaccharide binding
    		•  0.533047672054027 bayes_pls_golite062009
  • immunoglobulin binding
    		•  0.48272957113121 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  0.323725749644669 bayes_pls_golite062009
  • MHC class II receptor activity
    		•  0.251167772391909 bayes_pls_golite062009
  • platelet-derived growth factor receptor binding
    		•  0.1619066412638 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  0.0606967061070782 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  0.01716416477363 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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