Protein Overview: dpn-PA

General Information:
Name(s) found:	dpn-PA / FBpp0087879 [FlyBase]
Description(s) found: Found 23 descriptions. SHOW ALL	The gene deadpan is referred to in FlyBase by the symbol Dmel\dpn (CG8704, FBgn0010109). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4116476..4119832. It has the cytological map location 44C2. Based on sequence similarity, it is predicted to have molecular function</span>: DNA binding; transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; adult locomotory behavior; dosage compensation; sex determination, establishment of X:A ratio; larval locomotory behavior. 13 alleles are reported. The phenotype of these alleles is annotated with: macrochaeta. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	435 amino acids
Gene Ontology:
Cellular Component:	nucleus [IC][IEA]
Biological Process:	negative regulation of transcription from RNA polymerase II promoter [ISS] dosage compensation [IMP] negative regulation of transcription [NAS] larval locomotory behavior [IMP] regulation of transcription, DNA-dependent [IEA] sex determination, establishment of X:A ratio [IGI][IMP][NAS] adult locomotory behavior [IMP] sex determination [NAS] regulation of transcription [IEA] dendrite morphogenesis [IMP]
Molecular Function:	DNA binding [ISS] RNA polymerase II transcription factor activity [NAS] specific RNA polymerase II transcription factor activity [NAS] transcription repressor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYKNDINSD DDFDCSNGYS DSYGSNGRMS NPNGLSKAEL RKTNKPIMEK RRRARINHCL  60
   61 NELKSLILEA MKKDPARHTK LEKADILEMT VKHLQSVQRQ QLNMAIQSDP SVVQKFKTGF 120
  121 VECAEEVNRY VSQMDGIDTG VRQRLSAHLN QCANSLEQIG SMSNFSNGYR GGLFPATAVT 180
  181 AAPTPLFPSL PQDLNNNSRT ESSAPAIQMG GLQLIPSRLP SGEFALIMPN TGSAAPPPGP 240
  241 FAWPGSAAGV AAGTASAALA SIANPTHLND YTQSFRMSAF SKPVNTSVPA NLPENLIHTL 300
  301 PGQTQLPVKN STSPPLSPIS SISSHCEESR AASPTVDVMS KHSFAGVFST PPPTSAETSF 360
  361 NTSGSLNLSA GSHDSSGCSR PLAHLQQQQV SSTSGIAKRD REAEAESSDC SLDEPSSKKF 420
  421 LAGAIEKSSS AWRPW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
transcription regulator activity	5.38658950816179	bayes_pls_golite062009
DNA binding	5.18654839258297	bayes_pls_golite062009
nucleic acid binding	5.05768805749761	bayes_pls_golite062009
transcription factor activity	4.78039531631248	bayes_pls_golite062009
binding	3.81829206350975	bayes_pls_golite062009
RNA polymerase II transcription factor activity	3.39500382187264	bayes_pls_golite062009
transcription factor binding	2.61163564741984	bayes_pls_golite062009
transcription repressor activity	2.58751248599889	bayes_pls_golite062009
transcription activator activity	2.5495467409976	bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding	2.42306484786159	bayes_pls_golite062009
sequence-specific DNA binding	2.31910036997977	bayes_pls_golite062009
transcription corepressor activity	2.03674713048499	bayes_pls_golite062009
protein binding	1.59929864805879	bayes_pls_golite062009
transcription cofactor activity	1.52770895937238	bayes_pls_golite062009
promoter binding	0.8576109846276	bayes_pls_golite062009
transcription coactivator activity	0.3513586903977	bayes_pls_golite062009

Term	Confidence	Notes
transcription regulator activity	4.32360164200263	bayes_pls_golite062009
DNA binding	4.02051725052534	bayes_pls_golite062009
nucleic acid binding	3.93314497121404	bayes_pls_golite062009
transcription factor activity	3.47415635303836	bayes_pls_golite062009
binding	3.22662593014843	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.49509042716951	bayes_pls_golite062009
transcription repressor activity	2.02281452178123	bayes_pls_golite062009
protein binding	1.46569798429756	bayes_pls_golite062009
sequence-specific DNA binding	0.531186377572287	bayes_pls_golite062009
transcription factor binding	0.507261685411423	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.73

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..103]	PSI-BLAST	13.0	Usf B/HLH domain
2	View Details	[104..203]	PSI-BLAST	4.522879	No description for 2db7A was found.
3	View Details	[204..252]	deduced	N/A	No confident structure predictions are available.
4	View Details	[253..435]	FFAS03	1.09	No description for 2j63A was found.

Protein Overview: dpn-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: