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Protein Overview: Gapdh1-PA, Gapdh1-PB

General Information:
Name(s) found: Gapdh1-PB / FBpp0099914 [FlyBase]
Gapdh1-PA / FBpp0087977 [FlyBase]
Description(s) found:
Found 39 descriptions.
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  • The gene Glyceraldehyde 3 phosphate dehydrogenase 1 is referred to in FlyBase by the symbol Dmel\Gapdh1 (CG12055, FBgn0001091). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3679403..3680885. It has the cytological map location 43E17. There is experimental evidence that it has the molecular function</span>: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity. There is experimental evidence that it is involved in the biological process</span>: glycolysis. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Glyceraldehyde 3 phosphate dehydrogenase 1 is referred to in FlyBase by the symbol Dmel\Gapdh1 (CG12055, FBgn0001091). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3679403..3680885. It has the cytological map location 43E17. There is experimental evidence that it has the molecular function</span>: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity. There is experimental evidence that it is involved in the biological process</span>: glycolysis. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 332 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    cytoplasm [NAS]
    Biological Process: glycolysis [IEP][NAS]
    oxidation reduction [IEA]
    Molecular Function: NAD or NADH binding [IEA]
    glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKIGINGFG RIGRLVLRAA IDKGASVVAV NDPFIDVNYM VYLFKFDSTH GRFKGTVAAE  60
   61 GGFLVVNGQK ITVFSERDPA NINWASAGAE YVVESTGVFT TIDKASTHLK GGAKKVIISA 120
  121 PSADAPMFVC GVNLDAYSPD MKVVSNASCT TNCLAPLAKV INDNFEIVEG LMTTVHATTA 180
  181 TQKTVDGPSG KLWRDGRGAA QNIIPAATGA AKAVGKVIPA LNGKLTGMAF RVPTPNVSVV 240
  241 DLTVRLGKGA TYDEIKAKVE EASKGPLKGI LGYTDEEVVS TDFFSDTHSS VFDAKAGISL 300
  301 NDKFVKLISW YDNEFGYSNR VIDLIKYMQS KD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..332] PSI-BLAST 139.0 Crystal Structure Of Human Placental Glyceraldehyde-3-Phosphate Dehydrogenase At 1.75 Resolution

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glyceraldehyde-3-phosphate dehydrogenase activity
    		•  6.40381118887682 bayes_pls_golite062009
  • glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
    		•  5.96956214078036 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.00402564572912 bayes_pls_golite062009
  • 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
    		•  3.16750187025282 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  2.70673476015931 bayes_pls_golite062009
  • catalytic activity
    		•  2.54843319568228 bayes_pls_golite062009
  • glucose-6-phosphate dehydrogenase activity
    		•  2.2713146106379 bayes_pls_golite062009
  • inositol-3-phosphate synthase activity
    		•  2.2178883592085 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.90939908578582 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  1.66955978224275 bayes_pls_golite062009
  • DNA binding
    		•  1.61355789916908 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.48478425318425 bayes_pls_golite062009
  • hydrolase activity
    		•  1.40468563568607 bayes_pls_golite062009
  • binding
    		•  1.22114607236074 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  1.16811519855038 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.11682034462164 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.03017667696669 bayes_pls_golite062009
  • transcription factor activity
    		•  0.91090893050278 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.910536752370264 bayes_pls_golite062009
  • signal transducer activity
    		•  0.910536752370264 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  0.88293430762998 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.74536049628503 bayes_pls_golite062009
  • intramolecular lyase activity
    		•  0.708206800759221 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.527946013169731 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  0.41382905800454 bayes_pls_golite062009
  • receptor activity
    		•  0.388215697182664 bayes_pls_golite062009
  • structural molecule activity
    		•  0.345975336806588 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  0.331048046502169 bayes_pls_golite062009
  • collagen binding
    		•  0.30621400535957 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.211380641599388 bayes_pls_golite062009
  • NADPH:quinone reductase activity
    		•  0.136079082491021 bayes_pls_golite062009
  • glucose binding
    		•  0.13030486887358 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle