Protein Overview: Bap170-PA

General Information:
Name(s) found:	Bap170-PA / FBpp0085442 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7302272\|gb\|AAF57363.1\| brahma associated protein 170kD [Drosophila melanogaster] [NCBI NR] gi\|19921692\|ref\|NP_610216.1\| brahma associated protein 170kD [Drosophila melanogaster] [NCBI NR] The gene Brahma associated protein 170kD is referred to in FlyBase by the symbol Dmel\Bap170 (CG3274, FBgn0042085). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2524023..2529866. It has the cytological map location 42B2. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: protein stabilization; positive regulation of transcription, DNA-dependent; phagocytosis, engulfment. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG3274-PA translation from_gene[CG3274 BcDNA:GH12174 FBgn0027541] seq_release:3 mol_weight=183031 cds_boundaries:(2R:1,697,591..1,703,185[+]) aa_length:1688 transcript_info:[CG3274-RA seq_release:3] gene_info:[gene symbol:BcDNA:GH12174 FBgn0027541 gen [hmr_yeast5_DM3-1_pombe.fasta] (Q9V9D0) BCDNA:GH12174 protein [DrosMelano7227.FASTAC.txt] (AE003789) BcDNA:GH12174 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG3274-PA [Drosophila melanogaster]gi\|19921692\|ref\|NP_610216.1\| CG3274-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2R:join(2524194..2524435,2524500..2525515,2525686..2528492,2528790..2529791); ID=FBpp0085442; name=Bap170-PA; parent=FBgn0042085,FBtr0086107; dbxref=FlyBase:FBpp0085442,FlyBase_Annotation_IDs:CG3274-PA,GB_protein:AAF57363.1,REFSEQ:NP_610 [fly-100309-contam.fasta] CG3274-PA [Drosophila melanogaster] [nr-271106-contam.fasta] Brahma associated protein 170kD CG3274-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2R:join(2524194..2524435,2524500..2525515,2525686..2528492,2528790..2529791); ID=FBpp0085442; name=Bap170-PA; parent=FBgn0042085,FBtr0086107; dbxref=FlyBase:FBpp0085442,FlyBase_Annotation_IDs:CG3274-PA,GB_protein:AAF57363.1,REFSEQ:NP_610216,GB_protein:AAF57363; MD5=18c218fb7c831741d2237baf9469f7ef; length=1688; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2R:join(2524194..2524435,2524500..2525515,2525686..2528492,2528790..2529791); ID=FBpp0085442; name=Bap170-PA; parent=FBgn0042085,FBtr0086107; dbxref=FlyBase:FBpp0085442,FlyBase_Annotation_IDs:CG3274-PA,GB_protein:AAF57363.1,REFSEQ:NP_610216,GB_protein:AAF57363; MD5=18c218fb7c831741d2237baf9469f7ef; length=1688; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Brahma associated protein 170kD OS=Drosophila melanogaster GN=Bap170 PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2R:join(2524194..2524435,2524500..2525515,2525686..2528492,2528790..2529791); ID=FBpp0085442; name=Bap170-PA; parent=FBgn0042085,FBtr0086107; dbxref=FlyBase:FBpp0085442,FlyBase_Annotation_IDs:CG3274-PA,GB_protein:AAF57363.1,REFSEQ:NP_610216,GB_protein:AAF57363,FlyMine:FBpp0085442,modMine:FBpp0085442; MD5=18c218fb7c831741d2237baf9469f7ef; length=1688; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] brahma associated protein 170kD [Drosophila melanogaster] [RJAZ10-comet.fasta] type=protein; loc=2R:join(6636689..6636930,6636995..6638010,6638181..6640987,6641285..6642286); ID=FBpp0085442; name=Bap170-PA; parent=FBgn0042085,FBtr0086107; dbxref=FlyBase:FBpp0085442,FlyBase_Annotation_IDs:CG3274-PA,GB_protein:AAF57363.1,REFSEQ:NP_610216,GB_protein:AAF57363,FlyMine:FBpp0085442,modMine:FBpp0085442; MD5=18c218fb7c831741d2237baf9469f7ef; length=1688; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:join(6636689..6636930,6636995..6638010,6638181..6640987,6641285..6642286); ID=FBpp0085442; name=Bap170-PA; parent=FBgn0042085,FBtr0086107; dbxref=FlyBase:FBpp0085442,FlyBase_Annotation_IDs:CG3274-PA,GB_protein:AAF57363.1,REFSEQ:NP_610216,GB_protein:AAF57363,FlyMine:FBpp0085442,modMine:FBpp0085442; MD5=18c218fb7c831741d2237baf9469f7ef; length=1688; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Brahma associated protein 170kD OS=Drosophila melanogaster GN=Bap170 PE=1 SV=1 [DROME.fasta.20160308] FBpp0085442 type=protein; loc=2R:join(6636689..6636930,6636995..6638010,6638181..6640987,6641285..6642286); ID=FBpp0085442; name=Bap170-PA; parent=FBgn0042085,FBtr0086107; dbxref=FlyBase:FBpp0085442,FlyBase_Annotation_IDs:CG3274-PA,GB_protein:AAF57363.1,REFSEQ:NP_610216,GB_protein:AAF57363,FlyMine:FBpp0085442,modMine:FBpp0085442; MD5=18c218fb7c831741d2237baf9469f7ef; length=1688; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2R:join(6636689..6636930,6636995..6638010,6638181..6640987,6641285..6642286); ID=FBpp0085442; name=Bap170-PA; parent=FBgn0042085,FBtr0086107; dbxref=FlyBase:FBpp0085442,FlyBase_Annotation_IDs:CG3274-PA,GB_protein:AAF57363.1,REFSEQ:NP_610216,GB_protein:AAF57363,UniProt/TrEMBL:A1Z6M0,FlyMine:FBpp0085442,modMine:FBpp0085442; MD5=18c218fb7c831741d2237baf9469f7ef; length=1688; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1688 amino acids
Gene Ontology:
Cellular Component:	brahma complex [IDA]
Biological Process:	phagocytosis, engulfment [IMP] positive regulation of transcription, DNA-dependent [IDA] protein stabilization [IMP]
Molecular Function:	DNA binding [IEA] zinc ion binding [IEA] protein binding [IPI] transcription coactivator activity [IC]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATTIDNVR VLLQSLPAAA VNSATQPGDL QTPGKIAAPA TPLRAKNPAQ LQIMPEKVEE  60
   61 MPPSPPEEFW RDLQQFHERR GTPLTQPARI SGKHVDLYKL YNEVTERGGF NKVTMRDEWD 120
  121 EVYSAMETLR ERCVNGTASI KHIYRRYLDK YERLNFFGED PDKMEALEAA IEIVEMGGGR 180
  181 SRSRFLAGAG GGLGSIFGSA HSTLPAVPMA YNQRQHSVNV ERRRQYKMST QLHRHSSYEK 240
  241 LLLSLLSPLP NEQDFAINVC TLMANEARHT LQLSECPKLL DVLLAHLGVY ADFTMRQLFQ 300
  301 HSYTEVRHHS QLSFWRDLLH DKPQVLELYT DEQAWLDNGL ISKEDGENSA ARSELLAACD 360
  361 ELHFLNLRRS NGTDERMGQR VLQIVQLVRT LSFHQENHAL LASNRTLWRY LVMGANVRWS 420
  421 NIHIQALETA GNLAQQFELL DPTTDELSRN LLATLCEGID SNDRAVIMSC LEILYKLCGR 480
  481 EGNSQHINRC LGLDFYQRAM LLLSLTDVMM IIFTLEAVYA LSALGARPCS MLMQVRGLID 540
  541 QLVTLITVEA QSYGTGGCIL MRVVEVFPGN MAASLAQNMP AILAPGPTSL TTLPTSLQVA 600
  601 VKPPAVLPTP TPAQTQVLPH GEQTPLVTAL PGLPMPSLPQ VQLPVPSLPQ VQLPPIAATV 660
  661 TLPSLPSASQ SFTHEDEQYA LAWLGATYER AGNGNDLRVE QAELYRIYLS HCQKAGKLSV 720
  721 VNHMQFPRLV RLIFNQSVGP VIVRHLDGIE LPGTYYVGIR MRAQPLAMQQ RPTPSIVPVK 780
  781 KDTPILPKQP FSDPVQTEVA SEESVSSAVT PPPSSSLIKS LLANKVTERQ QKQKAQAQTP 840
  841 QPPALVATTA SGTNATQPIK VTSTAISAFV NNPLMQHTPV KVGQTTIKPL HPQMAIEKKP 900
  901 ITDSAPPPLA PLSGANVVTK DASGRTLIIA SAAAKRKLTI DEEQNKRLAL DAAASSSSSS 960
  961 SSGGKEEAQV TPSKNAANLY ADLAASILED EDMDDVPPLA KPSQEQSQQH PQQAQQLQLI1020
 1021 PAKVQPTQRQ LVFPGSNVVS PAPHSQLKLA TTATIKTDQG LQTVPVILQP KTAMDSTPAP1080
 1081 QTQYVLATNQ QGQTYLVAQQ PTIPTSTQSA PPTLLVTQTP QQQTKTIIIL QQPGGVSAAN1140
 1141 VAGTQKMIMT TAQGQQVLVT TTTAPQLAQP RTSTPQQQIF IAPQRPVPAL GAGQMSPSLL1200
 1201 SQLNQIPATI KLHQPQPQPQ LVSPQLAPQQ RLVAAKPGAS LPIPQLQQHQ SIIQQHIISG1260
 1261 PSTPTSTVGG TVGGEKRQVI LGGIKETTLI TQTSATPAPL QQSQLNSQTI ITQSPTSTAI1320
 1321 VGGVALQQQH HIRSVLDQQQ QHHPSIIQQK ITMPAISEAT KPKIAPVPVS PTVTLLAKKP1380
 1381 APPQPAQVSS PKPSVTQAVV VTTSGTSDST EGGKTVVLAT SEAKPAESEV VAQTVVPPAV1440
 1441 VTTGPSSSSL VVSQSVYAAS GPNANPTPSP MPVDANWLYI CDWRNCPRKK FKSLNELQYH1500
 1501 VCSVHCPDHL DSDADIYCQW GSGPNFCDNR ARKRYSLMTH LIDRHLTTEN LRASVQRRLA1560
 1561 TGIHNVAPTQ APVTIVRNEG HAQRLAGGAT GSPSGPASAV PVVGSAAMQA MNRHTTDYTN1620
 1621 AKELMDENEG PVTKSIRLTA ALIIRNLVTY SATAKRSLKR YESRLANVAF SNVEASGVLS1680
 1681 HIMYELSQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..218]	PSI-BLAST	40.30103	No description for 2cxyA was found.
2	View Details	[219..584]	FFAS03	2.4	Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
3	View Details	[585..1601]	PSI-BLAST	17.39794	No description for 1y0fA was found.
4	View Details	[1602..1688]	deduced	N/A	No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.27

Protein Overview: Bap170-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: