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Protein Overview: Bap170-PA

General Information:
Name(s) found: Bap170-PA / FBpp0085442 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene Brahma associated protein 170kD is referred to in FlyBase by the symbol Dmel\Bap170 (CG3274, FBgn0042085). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2524023..2529866. It has the cytological map location 42B2. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: protein stabilization; positive regulation of transcription, DNA-dependent; phagocytosis, engulfment. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1688 amino acids

    Gene Ontology:
    Cellular Component: brahma complex [IDA]
    Biological Process: phagocytosis, engulfment [IMP]
    positive regulation of transcription, DNA-dependent [IDA]
    protein stabilization [IMP]
    Molecular Function: DNA binding [IEA]
    zinc ion binding [IEA]
    protein binding [IPI]
    transcription coactivator activity [IC]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATTIDNVR VLLQSLPAAA VNSATQPGDL QTPGKIAAPA TPLRAKNPAQ LQIMPEKVEE  60
   61 MPPSPPEEFW RDLQQFHERR GTPLTQPARI SGKHVDLYKL YNEVTERGGF NKVTMRDEWD 120
  121 EVYSAMETLR ERCVNGTASI KHIYRRYLDK YERLNFFGED PDKMEALEAA IEIVEMGGGR 180
  181 SRSRFLAGAG GGLGSIFGSA HSTLPAVPMA YNQRQHSVNV ERRRQYKMST QLHRHSSYEK 240
  241 LLLSLLSPLP NEQDFAINVC TLMANEARHT LQLSECPKLL DVLLAHLGVY ADFTMRQLFQ 300
  301 HSYTEVRHHS QLSFWRDLLH DKPQVLELYT DEQAWLDNGL ISKEDGENSA ARSELLAACD 360
  361 ELHFLNLRRS NGTDERMGQR VLQIVQLVRT LSFHQENHAL LASNRTLWRY LVMGANVRWS 420
  421 NIHIQALETA GNLAQQFELL DPTTDELSRN LLATLCEGID SNDRAVIMSC LEILYKLCGR 480
  481 EGNSQHINRC LGLDFYQRAM LLLSLTDVMM IIFTLEAVYA LSALGARPCS MLMQVRGLID 540
  541 QLVTLITVEA QSYGTGGCIL MRVVEVFPGN MAASLAQNMP AILAPGPTSL TTLPTSLQVA 600
  601 VKPPAVLPTP TPAQTQVLPH GEQTPLVTAL PGLPMPSLPQ VQLPVPSLPQ VQLPPIAATV 660
  661 TLPSLPSASQ SFTHEDEQYA LAWLGATYER AGNGNDLRVE QAELYRIYLS HCQKAGKLSV 720
  721 VNHMQFPRLV RLIFNQSVGP VIVRHLDGIE LPGTYYVGIR MRAQPLAMQQ RPTPSIVPVK 780
  781 KDTPILPKQP FSDPVQTEVA SEESVSSAVT PPPSSSLIKS LLANKVTERQ QKQKAQAQTP 840
  841 QPPALVATTA SGTNATQPIK VTSTAISAFV NNPLMQHTPV KVGQTTIKPL HPQMAIEKKP 900
  901 ITDSAPPPLA PLSGANVVTK DASGRTLIIA SAAAKRKLTI DEEQNKRLAL DAAASSSSSS 960
  961 SSGGKEEAQV TPSKNAANLY ADLAASILED EDMDDVPPLA KPSQEQSQQH PQQAQQLQLI1020
 1021 PAKVQPTQRQ LVFPGSNVVS PAPHSQLKLA TTATIKTDQG LQTVPVILQP KTAMDSTPAP1080
 1081 QTQYVLATNQ QGQTYLVAQQ PTIPTSTQSA PPTLLVTQTP QQQTKTIIIL QQPGGVSAAN1140
 1141 VAGTQKMIMT TAQGQQVLVT TTTAPQLAQP RTSTPQQQIF IAPQRPVPAL GAGQMSPSLL1200
 1201 SQLNQIPATI KLHQPQPQPQ LVSPQLAPQQ RLVAAKPGAS LPIPQLQQHQ SIIQQHIISG1260
 1261 PSTPTSTVGG TVGGEKRQVI LGGIKETTLI TQTSATPAPL QQSQLNSQTI ITQSPTSTAI1320
 1321 VGGVALQQQH HIRSVLDQQQ QHHPSIIQQK ITMPAISEAT KPKIAPVPVS PTVTLLAKKP1380
 1381 APPQPAQVSS PKPSVTQAVV VTTSGTSDST EGGKTVVLAT SEAKPAESEV VAQTVVPPAV1440
 1441 VTTGPSSSSL VVSQSVYAAS GPNANPTPSP MPVDANWLYI CDWRNCPRKK FKSLNELQYH1500
 1501 VCSVHCPDHL DSDADIYCQW GSGPNFCDNR ARKRYSLMTH LIDRHLTTEN LRASVQRRLA1560
 1561 TGIHNVAPTQ APVTIVRNEG HAQRLAGGAT GSPSGPASAV PVVGSAAMQA MNRHTTDYTN1620
 1621 AKELMDENEG PVTKSIRLTA ALIIRNLVTY SATAKRSLKR YESRLANVAF SNVEASGVLS1680
 1681 HIMYELSQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..218] PSI-BLAST 40.30103 No description for 2cxyA was found.
    2 View Details [219..584] FFAS03 2.4 Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
    3 View Details [585..1601] PSI-BLAST 17.39794 No description for 1y0fA was found.
    4 View Details [1602..1688] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.96084803796407 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.69616509670156 bayes_pls_golite062009
  • protein binding
    		•  2.66176697577398 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.19067997822967 bayes_pls_golite062009
  • DNA binding
    		•  1.96172460362671 bayes_pls_golite062009
  • transporter activity
    		•  1.85346023606579 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.51565516399356 bayes_pls_golite062009
  • transcription activator activity
    		•  1.47146260606784 bayes_pls_golite062009
  • protein transporter activity
    		•  1.38613229168078 bayes_pls_golite062009
  • transcription factor activity
    		•  1.21493607378314 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.710528717985301 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.39311980867126 bayes_pls_golite062009
  • RNA binding
    		•  0.243875756041061 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.109435859778099 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0728493557966827 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0641324729536009 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0615190129942244 bayes_pls_golite062009
  • transcription factor binding
    		•  8.79739237675814E-4 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.27

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle