Protein Overview: Dif-PB, Dif-PA, ...

General Information:
Name(s) found:	Dif-PD / FBpp0290793 [FlyBase] Dif-PB / FBpp0080562 [FlyBase] Dif-PA / FBpp0080561 [FlyBase]
Description(s) found: Found 45 descriptions. SHOW ALL	The gene Dorsal-related immunity factor is referred to in FlyBase by the symbol Dmel\Dif (CG6794, FBgn0011274). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:17413248..17439923. It has the cytological map location 36C7-36C8. There is experimental evidence that it has the molecular function</span>: transcription factor activity; sequence-specific DNA binding; transcription activator activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: defense response to fungus; positive regulation of gene-specific transcription from RNA polymerase II promoter; positive regulation of gene expression; cellular response to DNA damage stimulus; defense response to Gram-positive bacterium; antifungal peptide production; regulation of hemocyte proliferation; lamellocyte differentiation; plasmatocyte differentiation. 22 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene Dorsal-related immunity factor is referred to in FlyBase by the symbol Dmel\Dif (CG6794, FBgn0011274). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:17413248..17439923. It has the cytological map location 36C7-36C8. There is experimental evidence that it has the molecular function</span>: transcription factor activity; sequence-specific DNA binding; transcription activator activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: defense response to fungus; positive regulation of gene-specific transcription from RNA polymerase II promoter; positive regulation of gene expression; cellular response to DNA damage stimulus; defense response to Gram-positive bacterium; antifungal peptide production; regulation of hemocyte proliferation; lamellocyte differentiation; plasmatocyte differentiation. 22 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene Dorsal-related immunity factor is referred to in FlyBase by the symbol Dmel\Dif (CG6794, FBgn0011274). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:17413248..17439923. It has the cytological map location 36C7-36C8. There is experimental evidence that it has the molecular function</span>: transcription factor activity; sequence-specific DNA binding; transcription activator activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: defense response to fungus; positive regulation of gene-specific transcription from RNA polymerase II promoter; positive regulation of gene expression; cellular response to DNA damage stimulus; defense response to Gram-positive bacterium; antifungal peptide production; regulation of hemocyte proliferation; lamellocyte differentiation; plasmatocyte differentiation. 22 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	667 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][NAS][TAS] cytoplasm [IDA][NAS][TAS]
Biological Process:	Toll signaling pathway [NAS][TAS] regulation of transcription, DNA-dependent [IEA] response to fungus [TAS] plasmatocyte differentiation [IMP] lamellocyte differentiation [IMP] defense response [NAS][TAS] antifungal peptide production [IMP] regulation of transcription [IEA] response to DNA damage stimulus [IMP] positive regulation of antifungal peptide biosynthetic process [TAS] immune response [NAS][TAS] innate immune response [NAS][TAS] positive regulation of gene expression [IGI] regulation of hemocyte proliferation [IDA] positive regulation of gene-specific transcription from RNA polymerase II promoter [IDA] defense response to fungus [IMP] defense response to Gram-positive bacterium [IMP]
Molecular Function:	DNA binding [IDA] transcription factor activity [IDA][NAS] sequence-specific DNA binding [IDA] transcription activator activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFEEAFGDIQ EIINASMELN GGATGGGSVA GAVGGGGAAH HILSQSTSLP VMPSHIPLHL  60
   61 QNQNMNQNLP EPSARSGPHL RIVEEPTSNI IRFRYKCEGR TAGSIPGMNS SSETGKTFPT 120
  121 IEVCNYDGPV IIVVSCVTSD EPFRQHPHWL VSKEEADACK SGIYQKKLPP EERRLVLQKV 180
  181 GIQCAKKLEM RDSLVERERR NIDPFNAKFD HKDQIDKINR YELRLCYQAF ITVGNSKVPL 240
  241 DPIVSSPIYG KSSELTITRL CSCAATANGG DEIIMLCEKI AKDDIEVRFY ETDKDGRETW 300
  301 FANAEFQPTD VFKQMAIAFK TPRYRNTEIT QSVNVELKLV RPSDGATSAP LPFEYYPNPE 360
  361 LLTKHNRRVA QKTVESLKRS LMSTNLHPSK QVKTSSQYTI FSKPQIATTT PQTQVSPGMP 420
  421 LMFPGGSPNF VQDIKMENGF MDVDSQSSQC PSVERNFASP RSNCSTVDSI PPMQMGQNQT 480
  481 HLYLPDATNF TFNGNFASPS SNCSTVDSIP PFQIGQRNNH MYLPENSNFP VNGCSPTHFS 540
  541 GGSMTPINNN NNVLINNNNN DFLSQKMSAI SIPPQGNFGI KQVYQQTQQF LPQLQPESIP 600
  601 YLAQSHPEQS QYQQQQQPQE QQPPADEPTQ SFSDLISSSI GMAPIDTSEL IQDIEAELNS 660
  661 LGIQPFK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Dif-PB, Dif-PA, ...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: