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Protein Overview: smt3-PA

General Information:
Name(s) found: smt3-PA / FBpp0078984 [FlyBase]
Description(s) found:
Found 30 descriptions.
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  • The gene smt3 is referred to in FlyBase by the symbol Dmel\smt3 (CG4494, FBgn0026170). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:6966776..6967593. It has the cytological map location 27C7. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: cell cycle; cell cycle process; mitotic cell cycle; transport; biopolymer modification; regulation of kinase activity; regionalization; positive regulation of signal transduction; protein localization in nucleus; anatomical structure development. 24 alleles are reported. The phenotypes of these alleles are annotated with: egg; wing; wing pouch; egg chamber; dorsal appendage; crystal cell. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 90 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    condensed nuclear chromosome, centromeric region [IDA]
    midbody [IDA]
    nucleolus [IDA]
    outer kinetochore of condensed chromosome [IDA]
    condensed nuclear chromosome [IDA]
    Biological Process: positive regulation of MAP kinase activity [IMP]
    M phase of mitotic cell cycle [IMP]
    phagocytosis, engulfment [IMP]
    protein import into nucleus [IGI][IPI]
    mitotic spindle organization [IMP]
    syncytial blastoderm mitotic cell cycle [IMP]
    protein modification process [IGI][IPI][ISS]
    anterior/posterior pattern formation [IMP]
    positive regulation of Ras protein signal transduction [IMP]
    dorsal appendage formation [IMP]
    mitotic cell cycle [IMP]
    Molecular Function: protein binding [IPI][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDEKKGGET EHINLKVLGQ DNAVVQFKIK KHTPLRKLMN AYCDRAGLSM QVVRFRFDGQ  60
   61 PINENDTPTS LEMEEGDTIE VYQQQTGGAP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..90] PSI-BLAST 23.39794 No description for 2awtA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • SUMO ligase activity
    		•  3.84399877513864 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  3.71144418714309 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  2.89535476350045 bayes_pls_golite062009
  • binding
    		•  2.786655943372 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  2.72499875710239 bayes_pls_golite062009
  • protein tag
    		•  2.3067732197076 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.21955949922709 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.9984951714209 bayes_pls_golite062009
  • protein binding
    		•  1.86841453215444 bayes_pls_golite062009
  • DNA binding
    		•  1.86539227646379 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.34783881509181 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.753885975469065 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.729632027931987 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.65988002090613 bayes_pls_golite062009
  • signal transducer activity
    		•  0.65988002090613 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.62324312069889 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.599634454232833 bayes_pls_golite062009
  • structural molecule activity
    		•  0.576819726104993 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.570143717979967 bayes_pls_golite062009
  • protein kinase activity
    		•  0.325253662829604 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.249928925871521 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0871262449740772 bayes_pls_golite062009
  • enzyme binding
    		•  0.0454736496719529 bayes_pls_golite062009
  • tubulin binding
    		•  0.0390794819499503 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle